Psmc6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6

GeneMGI:1914339Synonyms: 2300001E01Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

17 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

decreased thigmotaxis2 supporting datasetsPsmc6tm1b(KOMP)WtsiheterozygoteEarly adult6.18x10-5 
hyperactivity7 supporting datasetsPsmc6tm1b(KOMP)WtsiheterozygoteEarly adult6.11x10-12 
preweaning lethality, complete penetrance1 supporting datasetPsmc6tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetPsmc6tm1b(KOMP)WtsihomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Psmc6tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Psmc6tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Psmc6tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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