Gene: Psmc6

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Name
proteasome (prosome, macropain) 26S subunit, ATPase, 6
MGI ID
MGI:1914339
Synonyms
2300001E01Rik
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
shortened RR interval Psmc6tm1b(KOMP)Wtsi HET Early adult 3.86×10-05
hyperactivity Psmc6tm1b(KOMP)Wtsi HET   Early adult 3.18×10-14
increased heart rate Psmc6tm1b(KOMP)Wtsi HET Early adult 4.10×10-05
preweaning lethality, complete penetrance Psmc6tm1b(KOMP)Wtsi HOM   Early adult 0.00
embryonic lethality prior to organogenesis Psmc6tm1b(KOMP)Wtsi HOM   E9.5 0.00
abnormal embryo size Psmc6tm1b(KOMP)Wtsi HET E9.5 0.00
increased exploration in new environment Psmc6tm1b(KOMP)Wtsi HET Early adult 2.76×10-06

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590)  (2/2)  Section images
Aorta 2 No  (1/590)  (2/2)  Section images
Brain 2 No  (3/590)  (2/2)  Section images
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590)  (1/2)  Section images
Cerebral cortex 2 No  (2/590) N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No N/A
Heart 2 No  (1/590)  Section images
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590) N/A
Kidney 2 No  (20/590)  (2/2)  Section images
Large intestine 2 No  (10/590)  (2/2)  Section images
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590)  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No  (1/2)  Section images
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/590) N/A
Ovary 2 No  (1/590)  (1/2)  Section images
Oviduct 2 No N/A
Pancreas 2 No  (5/590) N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/590)  (2/2)  Section images
Spinal cord 2 No  (2/590) N/A
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590)  (2/2)  Section images
Striatum 2 No  (3/590) N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (5/590)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/590) N/A
Trachea 2 No  (2/590) N/A
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506) N/A
Dorsal root ganglion 1  (1/61) N/A
Ear 2  (1/506) N/A
Embryo 2  (1/507) N/A
Eye 2  (1/506) N/A
Foot 2  (1/506) N/A
Forebrain 2  (1/506) N/A
Forelimb 2  (1/506) N/A
Fronto-nasal process 1  (1/62) N/A
Hand 2  (1/506) N/A
Head 2  (5/506) N/A
Heart 2  (1/506) N/A
Hindbrain 2  (6/506) N/A
Hindlimb 2  (1/506) N/A
Liver 2  (1/504) N/A
Lung 2  (1/504) N/A
Mandibular process 2  (1/506) N/A
Maxillary process 2  (1/506) N/A
Midbrain 2  (1/506) N/A
Nose 1  (1/76) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/506) N/A
Spinal cord 1  (1/73) N/A
Tail 2  (1/506) N/A
Tail somite 2  (1/506) N/A

 Associated Images

Original Image
Adult LacZ: LacZ Images Section
19 Images
X-ray: XRay Images Forepaw
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
8 Images
X-ray: XRay Images Skull Lateral Orientation
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Psmc6tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Psmc6tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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