The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
|Phenotype||System||Allele||Zyg||Sex||Life Stage||P Value|
|preweaning lethality, complete penetrance||Paicsem1(IMPC)Mbp||HOM||Early adult||0.00|
|embryonic growth retardation||Paicsem1(IMPC)Mbp||HET||E9.5||0.00|
|prenatal lethality prior to heart atrial septation||Paicsem1(IMPC)Mbp||HOM||E15.5||0.00|
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases associated to Paics by orthology or direct annotation.
The table below shows human diseases predicted to be associated to Paics by phenotypic similarity.
Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.
There is no histopathology data for Paics
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Paics.
There are 1 publication which use IMPC produced mice or data.
|Title||Journal||IMPC Allele||PubMed ID|
|Control of PD-L1 Expression by Oncogenic Activation of the AKT-mTOR Pathway in Non-Small Cell Lung Cancer.||Cancer research (December 2015)||Paicsem1(IMPC)Mbp||26637667|