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Genes Phenotypes

Gene: Mkrn2

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Name
makorin, ring finger protein, 2
MGI ID
MGI:1914277
Synonyms
2610002L04Rik
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (352) All data table (1863)
Expression & images (45) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased dendritic epidermal T cell number Mkrn2tm1b(KOMP)Wtsi HOM   Early adult 0.00
male infertility Mkrn2em1(IMPC)Wtsi HOM Early adult 0.00
male infertility Mkrn2tm1b(KOMP)Wtsi HOM Early adult 0.00
increased circulating alkaline phosphatase level Mkrn2tm1b(KOMP)Wtsi HOM Early adult 7.36×10-07
abnormal bone structure Mkrn2em1(IMPC)Wtsi HOM Early adult 6.28×10-06
abnormal auditory brainstem response Mkrn2tm1b(KOMP)Wtsi HOM   Early adult 1.61×10-11

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590)  (2/2) N/A
Aorta 2 No  (1/590)  (2/2) N/A
Blood vessel 2 No  (2/2) N/A
Bone 2 No  (2/2) N/A
Brain 2 No  (3/590)  (2/2) N/A
Brainstem 2 No  (2/590)  (2/2) N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (3/590)  (2/2) N/A
Cerebral cortex 2 No  (2/590)  (2/2) N/A
Eye 2 No  (2/2) N/A
Gall bladder 2 No  (2/2) N/A
Heart 2 No  (1/590)  (2/2) N/A
Hippocampus 2 No  (3/590)  (2/2) N/A
Hypothalamus 2 No  (2/590)  (2/2) N/A
Kidney 2 No  (20/590)  (2/2) N/A
Large intestine 2 No  (10/590)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590)  (2/2) N/A
Lung 2 No  (1/590)  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/590)  (2/2) N/A
Ovary 2 No  (1/590)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/590)  (2/2) N/A
Parathyroid gland 2 No  (2/2) N/A
Peripheral nervous system 2 No  (1/590)  (2/2) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590)  (2/2) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/590)  (2/2) N/A
Spinal cord 2 No  (2/590)  (2/2) N/A
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590)  (2/2) N/A
Striatum 2 No  (3/590)  (2/2) N/A
Testis 2 No  (5/590)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/590)  (2/2) N/A
Trachea 2 No  (2/590)  (2/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Mkrn2tm1b(KOMP)Wtsi
peripheral nervous system, trigeminal V nerve, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
eye, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
olfactory lobe, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
kidney, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
spinal cord, HET, Male, WTSI

View all 21 images

Mkrn2tm1b(KOMP)Wtsi
kidney, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
spinal cord, HET, Male, WTSI
Mkrn2tm1b(KOMP)Wtsi
large intestine, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
oviduct, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
lung, HET, Female, WTSI

View all 15 images

Mkrn2tm1b(KOMP)Wtsi
large intestine, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
oesophagus, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
gall bladder, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
small intestine, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
peripheral nervous system, trigeminal V nerve, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
olfactory lobe, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
spinal cord, HET, Male, WTSI
Mkrn2tm1b(KOMP)Wtsi
brown adipose tissue, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
rib, cartilage tissue, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
inguinal fat pad, white adipose tissue, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
brown adipose tissue, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
inguinal fat pad, white adipose tissue, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
oviduct, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
testis, HET, Male, WTSI
Mkrn2tm1b(KOMP)Wtsi
lung, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
trachea, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
kidney, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
lower urinary tract, urinary bladder, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
heart, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
adrenal gland, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
skin, HET, Male, WTSI
Mkrn2tm1b(KOMP)Wtsi
rib, cartilage tissue, HET, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
eye, HET, Female, WTSI
No Embryo expression data was found for this gene.

 Associated Images

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X-ray: XRay Images Skull Lateral Orientation
28 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
30 Images
thumbnail
X-ray: XRay Images Whole Body Lateral Orientation
28 Images
thumbnail
Anti-nuclear antibody assay
9 Images
X-ray: XRay Images Forepaw
28 Images
thumbnail
DSS Histology
8 Images
thumbnail
X-ray: XRay Images Whole Body Dorso Ventral
28 Images
thumbnail
Eye Morphology: Images Slit Lamp
4 Images
thumbnail
Ear epidermis immunophenotyping
12 Images
Legacy Phenotype Associated Images
Mkrn2tm1b(KOMP)Wtsi
WT, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
WT, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
WT, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
WT, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
WT, Female, WTSI

View all 177 images

Mkrn2tm1b(KOMP)Wtsi
corneal vascularization, HOM, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
corneal opacity, HOM, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
mydriasis, HOM, Female, WTSI
Mkrn2em1(IMPC)Wtsi
eye discharge, HOM, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
TS20 oral cavity, HET, Male, WTSI
Mkrn2tm1b(KOMP)Wtsi
TS20 head, HET, Male, WTSI
Mkrn2tm1b(KOMP)Wtsi
TS20 heart, HET, Male, WTSI
Mkrn2tm1b(KOMP)Wtsi
TS20 chorioallantoic placenta, HET, Male, WTSI
Mkrn2tm1b(KOMP)Wtsi
head, abnormal snout morphology, HOM, Female, WTSI
Mkrn2em1(IMPC)Wtsi
abnormal snout morphology, short snout, head, HOM, Male, WTSI
Mkrn2tm1b(KOMP)Wtsi
fetal edema, hemorrhage, HOM, Female, WTSI
Mkrn2tm1b(KOMP)Wtsi
HOM, Male, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Mkrn2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Mkrn2em1(IMPC)Wtsi Exdel Mice
Mkrn2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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