Phenotype | System | Allele | Zyg | Sex | Life Stage | P Value |
---|---|---|---|---|---|---|
decreased dendritic epidermal T cell number | Mkrn2tm1b(KOMP)Wtsi | HOM | Early adult | 0.00 | ||
male infertility | Mkrn2em1(IMPC)Wtsi | HOM | Early adult | 0.00 | ||
male infertility | Mkrn2tm1b(KOMP)Wtsi | HOM | Early adult | 0.00 | ||
increased circulating alkaline phosphatase level | Mkrn2tm1b(KOMP)Wtsi | HOM | Early adult | 7.36×10-07 | ||
abnormal bone structure | Mkrn2em1(IMPC)Wtsi | HOM | Early adult | 6.28×10-06 | ||
abnormal auditory brainstem response | Mkrn2tm1b(KOMP)Wtsi | HOM | Early adult | 1.61×10-11 |
Gene: Mkrn2
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IMPC lacZ Expression Data
Anatomy | #HET Specimens | HOM Images? | WT Expr | Mutant Expr | Images |
---|---|---|---|---|---|
Adrenal gland | 2 | No | (3/590) | (2/2) | N/A |
Aorta | 2 | No | (1/590) | (2/2) | N/A |
Blood vessel | 2 | No | (2/2) | N/A | |
Bone | 2 | No | (2/2) | N/A | |
Brain | 2 | No | (3/590) | (2/2) | N/A |
Brainstem | 2 | No | (2/590) | (2/2) | N/A |
Brown adipose tissue | 2 | No | (2/2) | N/A | |
Cartilage tissue | 2 | No | (2/2) | N/A | |
Cerebellum | 2 | No | (3/590) | (2/2) | N/A |
Cerebral cortex | 2 | No | (2/590) | (2/2) | N/A |
Eye | 2 | No | (2/2) | N/A | |
Gall bladder | 2 | No | (2/2) | N/A | |
Heart | 2 | No | (1/590) | (2/2) | N/A |
Hippocampus | 2 | No | (3/590) | (2/2) | N/A |
Hypothalamus | 2 | No | (2/590) | (2/2) | N/A |
Kidney | 2 | No | (20/590) | (2/2) | N/A |
Large intestine | 2 | No | (10/590) | (2/2) | N/A |
Liver | 2 | No | N/A | ||
Lower urinary tract | 2 | No | (1/590) | (2/2) | N/A |
Lung | 2 | No | (1/590) | (2/2) | N/A |
Lymph node | 2 | No | N/A | ||
Mammary gland | 2 | No | N/A | ||
Esophagus | 2 | No | (2/2) | N/A | |
Olfactory lobe | 2 | No | (2/590) | (2/2) | N/A |
Ovary | 2 | No | (1/590) | (1/2) | N/A |
Oviduct | 2 | No | (1/2) | N/A | |
Pancreas | 2 | No | (5/590) | (2/2) | N/A |
Parathyroid gland | 2 | No | (2/2) | N/A | |
Peripheral nervous system | 2 | No | (1/590) | (2/2) | N/A |
Peyer's patch | 2 | No | N/A | ||
Pituitary gland | 2 | No | (1/590) | (2/2) | N/A |
Prostate gland | 2 | No | (12/590) | N/A | |
Skeletal muscle tissue | 2 | No | N/A | ||
Skin | 2 | No | (2/2) | N/A | |
Small intestine | 2 | No | (9/590) | (2/2) | N/A |
Spinal cord | 2 | No | (2/590) | (2/2) | N/A |
Spleen | 2 | No | (2/590) | N/A | |
Stomach | 2 | No | (13/590) | (2/2) | N/A |
Striatum | 2 | No | (3/590) | (2/2) | N/A |
Testis | 2 | No | (5/590) | (1/2) | N/A |
Thymus | 2 | No | N/A | ||
Thyroid gland | 2 | No | (16/590) | (2/2) | N/A |
Trachea | 2 | No | (2/590) | (2/2) | N/A |
Uterus | 2 | No | (1/2) | N/A | |
White adipose tissue | 2 | No | N/A |
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Associated Images
Legacy Phenotype Associated Images
Disease Models
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MGI Allele | Allele Type | Produced |
---|---|---|
Mkrn2tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (post-Cre) | Mice |
Mkrn2em1(IMPC)Wtsi | Exdel | Mice |
Mkrn2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Mice, Targeting vectors, ES Cells |
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