Gene: Med28

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Name
mediator complex subunit 28
MGI ID
MGI:1914249
Synonyms
Eg1 1500003D12Rik magicin
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to organogenesis Med28tm1.1(KOMP)Vlcg HOM   E9.5 0.00
abnormal spleen morphology Med28tm1.1(KOMP)Vlcg HET Early adult 0.00
increased body length Med28tm1.1(KOMP)Vlcg HET Early adult 1.63×10-06
embryonic lethality prior to tooth bud stage Med28tm1.1(KOMP)Vlcg HOM   E12.5 0.00
abnormal embryo size Med28tm1.1(KOMP)Vlcg HET E9.5 0.00
preweaning lethality, complete penetrance Med28tm1.1(KOMP)Vlcg HOM   Early adult 0.00
abnormal auditory brainstem response Med28tm1.1(KOMP)Vlcg HET   Early adult 2.81×10-06
small spleen Med28tm1.1(KOMP)Vlcg HET Early adult 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (3/590)  (3/4)  Wholemount images  Section images
Aorta 4 No  (1/590) N/A
Blood 4 No N/A
Bone marrow 4 No N/A
Brain 4 No  (3/590)  (2/4)  Wholemount images
Brainstem 4 No  (2/590) N/A
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No N/A
Cecum 4 No  (12/377)  (3/4)  Section images
Cerebellum 4 No  (3/590)  (4/4)  Wholemount images  Section images
Cerebral cortex 4 No  (2/590) N/A
Chest bone 4 No  (2/4)  Wholemount images
Colon 4 No  (12/127)  (3/4)  Section images
Diaphragm 4 No N/A
Duodenum 4 No  (2/127)  (1/4) N/A
Epididymis 4 No  (18/134)  (2/4)  Wholemount images  Section images
Esophagus 4 No  (7/415) N/A
Eye 4 No  (2/4)  Section images
Gall bladder 4 No N/A
Gonadal fat pad 4 No N/A
Harderian gland 4 No  (2/4)  Section images
Heart 4 No  (1/590) N/A
Hindlimb 4 No N/A
Hippocampus 4 No  (3/590) N/A
Hypothalamus 4 No  (2/590) N/A
Ileum 4 No  (14/127)  (3/4)  Section images
Jejunum 4 No  (6/127)  (2/4)  Section images
Kidney 4 No  (20/590)  (4/4)  Wholemount images  Section images
Large intestine 4 No  (10/590) N/A
Liver 4 No  (4/4)  Wholemount images  Section images
Lower urinary tract 4 No  (1/590) N/A
Lung 4 No  (1/590) N/A
Lymph node 4 No N/A
Mammary gland 4 No N/A
Mesenteric adipose tissue 4 No N/A
Mesenteric lymph node 4 No N/A
Midbrain 4 No  (4/4)  Wholemount images  Section images
Olfactory lobe 4 No  (2/590)  (4/4)  Wholemount images  Section images
Ovary 4 No  (1/590) N/A
Oviduct 4 No N/A
Pancreas 4 No  (5/590)  (2/4)  Wholemount images  Section images
Parathyroid gland 4 No N/A
Parotid gland 4 No N/A
Penis 4 No N/A
Peripheral nervous system 4 No  (1/590) N/A
Peyer's patch 4 No N/A
Pituitary gland 4 No  (1/590)  (3/4)  Wholemount images  Section images
Prostate gland 4 No  (12/590)  (1/4)  Section images
Quadriceps 4 No  (1/4)  Section images
Sciatic nerve 4 No N/A
Skeletal muscle 4 No N/A
Skin 4 No N/A
Small intestine 4 No  (9/590) N/A
Spinal cord 4 No  (2/590)  (3/4)  Wholemount images  Section images
Spleen 4 No  (2/590) N/A
Stomach 4 No  (13/590)  (4/4)  Wholemount images  Section images
Stomach pyloric region 4 No N/A
Striatum 4 No  (3/590) N/A
Sublingual gland 4 No  (1/4)  Section images
Submandibular gland 4 No  (2/132) N/A
Testis 4 No  (5/590)  (2/4)  Wholemount images  Section images
Thymus 4 No  (1/4) N/A
Thyroid gland 4 No  (16/590)  (1/4)  Wholemount images
Tongue 4 No  (5/127)  (2/4) N/A
Trachea 4 No  (2/590)  (3/4)  Wholemount images  Section images
Trigeminal V nerve 4 No N/A
Urinary bladder 4 No  (3/4)  Wholemount images  Section images
Uterus 4 No  (1/4) N/A
Vagina 4 No N/A
Vas deferens 4 No  (15/388)  (2/4)  Section images
Vascular system 4 No N/A
Vesicular gland 4 No N/A
White adipose tissue 4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/65) N/A
Brain 7  (6/506) N/A
Central nervous system ganglion 2  (1/74) N/A
Ear 7  (1/506) N/A
Embryo 7  (1/507)  (2/7) N/A
Eye 7  (1/506)  (2/7) N/A
Foot 7  (1/506) N/A
Forebrain 7  (1/506) N/A
Forelimb 7  (1/506)  (2/7) N/A
Gut 2  (1/60) N/A
Hand 7  (1/506) N/A
Head 7  (5/506) N/A
Heart 7  (1/506)  (2/7) N/A
Hindbrain 7  (6/506) N/A
Hindlimb 7  (1/506)  (2/7) N/A
Liver 7  (1/504) N/A
Lung 7  (1/504) N/A
Mandibular process 7  (1/506)  (2/7) N/A
Maxillary process 7  (1/506)  (2/7) N/A
Midbrain 7  (1/506) N/A
Nose 2  (1/76) N/A
Oral cavity 7  (1/504) Image Only N/A
Skeleton 2  (1/76)  (2/2) N/A
Skin 7  (1/506) N/A
Spinal cord 2  (1/73) N/A
Tail 7  (1/506) N/A
Tail somite 7  (1/506) N/A
Trachea 2  (1/60) N/A
Urinary system 2  (1/60)  (2/2) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
23 Images
Adult LacZ: LacZ Images Section
75 Images
Embryo LacZ: LacZ images wholemount
28 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Med28tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Med28tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Med28tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

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