Gene: Rnpepl1 MGI:1914170

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Gene Summary

Name:
arginyl aminopeptidase (aminopeptidase B)-like 1
Synonyms:
1110014H17Rik

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal lymph node morphology Rnpepl1em1(IMPC)Mbp HOM Early adult 0.00
enlarged lymph nodes Rnpepl1em1(IMPC)Mbp HOM Early adult 0.00

Download data as:  TSV  XLS

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Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Whole Body Lateral Orientation

10 Images

X-ray

XRay Images Whole Body Dorso Ventral

30 Images

Human diseases caused by Rnpepl1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Rnpepl1 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Immunodeficiency 32A
Lymphadenopathy OMIM:614893
Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Irf8 Deficiency
Lymphadenopathy ORPHA:319600
Immunodeficiency 38 With Basal Ganglia Calcification
Lymphadenopathy OMIM:616126
Reticuloendotheliosis, X-Linked
Hepatosplenomegaly, Lymphadenopathy OMIM:312500
Hepatic Venoocclusive Disease With Immunodeficiency
Absence of lymph node germinal center OMIM:235550
Squamous Cell Carcinoma Of The Esophagus
Lymphadenopathy ORPHA:99977
Pulmonary Nodular Lymphoid Hyperplasia
Mediastinal lymphadenopathy, Follicular hyperplasia ORPHA:60026
Fragile Site, Distamycin A Type, Rare, Fra(16)(Q22.1)
Abnormality of the lymph nodes OMIM:136580
Mantle Cell Lymphoma
Lymphadenopathy, Splenomegaly ORPHA:52416
Immunodeficiency 75
Hepatosplenomegaly, Follicular hyperplasia, Lymphadenopathy OMIM:619126
Kerion Celsi
Lymphadenopathy ORPHA:499
Apolipoprotein A-I Deficiency
Lymphadenopathy, Splenomegaly ORPHA:425
Kimura Disease
Follicular hyperplasia, Lymphadenopathy ORPHA:482
T-Cell Receptor-Alpha/Beta Deficiency
Lymphadenopathy OMIM:615387
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Positive, Nk Cell-Positive
Lymphadenopathy, Splenomegaly OMIM:608971
Adenocarcinoma Of The Esophagus
Lymphadenopathy ORPHA:99976
Mast Cell Sarcoma
Mediastinal lymphadenopathy, Lymphadenopathy, Splenomegaly ORPHA:66661
Deafness, Autosomal Dominant 34, With Or Without Inflammation
Lymphadenopathy OMIM:617772
Immunodeficiency 27B
Generalized lymphadenopathy OMIM:615978
Autoinflammation With Episodic Fever And Lymphadenopathy
Recurrent tonsillitis, Lymphadenopathy, Splenomegaly OMIM:618852
Immunodeficiency 63 With Lymphoproliferation And Autoimmunity
Lymphadenopathy, Splenomegaly OMIM:618495
Carcinoma Of Esophagus
Lymphadenopathy ORPHA:70482
Lymphoproliferative Syndrome 3
Hepatosplenomegaly, Lymphadenopathy OMIM:618261
Immunodeficiency With Hyper-Igm, Type 2
Lymphadenopathy OMIM:605258
Severe Combined Immunodeficiency With Sensitivity To Ionizing Radiation
Absent tonsils, Lymph node hypoplasia, Aplasia of the thymus OMIM:602450
Follicular Lymphoma
Mediastinal lymphadenopathy, Lymphadenopathy, Splenomegaly ORPHA:545
Autoimmune Hemolytic Anemia-Autoimmune Thrombocytopenia-Primary Immunodeficiency Syndrome
Lymphadenopathy, Splenomegaly ORPHA:444463
Nodular Lymphocyte Predominant Hodgkin Lymphoma
Lymphadenopathy, Splenomegaly ORPHA:86893
Granulomatous Slack Skin
Abnormality of the lymph nodes ORPHA:33111
Immunodeficiency With Hyper-Igm, Type 5
Lymphadenopathy OMIM:608106
Candidiasis, Familial, 2
Lymphadenopathy OMIM:212050
Familial Papillary Thyroid Carcinoma With Renal Papillary Neoplasia
Chronic noninfectious lymphadenopathy, Abnormality of the lymph nodes ORPHA:97290
Immunodeficiency 73C With Defective Neutrophil Chemotaxis And Hypogammaglobulinemia
Cervical lymphadenopathy OMIM:618987
Polyglucosan Body Myopathy 1 With Or Without Immunodeficiency
Lymphadenopathy OMIM:615895
Familial Papillary Or Follicular Thyroid Carcinoma
Chronic noninfectious lymphadenopathy, Abnormality of the lymph nodes ORPHA:319487
Rosaï-Dorfman Disease
Lymphadenopathy ORPHA:158014
Immunodeficiency 76
Lymphadenopathy, Splenomegaly OMIM:619164
Immunodeficiency 72 With Autoinflammation
Hepatosplenomegaly, Lymphadenopathy OMIM:618982
Mu-Heavy Chain Disease
Lymphadenopathy, Splenomegaly ORPHA:100024
Fish-Eye Disease
Lymphadenopathy, Splenomegaly ORPHA:79292
Immunodeficiency With Hyper-Igm, Type 3
Absence of lymph node germinal center OMIM:606843
Hodgkin Lymphoma
Lymphadenopathy, Splenomegaly ORPHA:98293
Immunodeficiency 14A, Autosomal Dominant
Lymphadenopathy, Splenomegaly OMIM:615513
Immunodeficiency 55
Lymphadenopathy OMIM:617827
Burkitt Lymphoma
Abnormality of the spleen, Abnormality of the lymph nodes ORPHA:543
Mycosis Fungoides
Lymphadenopathy OMIM:254400
Laryngeal Neuroendocrine Tumor
Chronic noninfectious lymphadenopathy ORPHA:100083
Immunodeficiency 78 With Autoimmunity And Developmental Delay
Fluctuating splenomegaly, Lymphadenopathy OMIM:619220
Alpha-Heavy Chain Disease
Lymphadenopathy, Splenomegaly ORPHA:100025
Immunodeficiency With Hyper-Igm, Type 4
Absence of lymph node germinal center OMIM:608184
Lcat Deficiency
Lymphadenopathy, Splenomegaly ORPHA:650
Hemophagocytic Lymphohistiocytosis, Familial, 5, With Or Without Microvillus Inclusion Disease
Hepatosplenomegaly, Lymphadenopathy, Splenomegaly OMIM:613101
Pfapa Syndrome
Lymphadenopathy, Splenomegaly ORPHA:42642
Proteasome-Associated Autoinflammatory Syndrome 2
Lymphadenopathy OMIM:618048
Immunodeficiency 64
Splenomegaly, Mediastinal lymphadenopathy, Hepatosplenomegaly, Lymphadenopathy, Cervical lymphade... OMIM:618534
Hemophagocytic Lymphohistiocytosis, Familial, 4
Lymphadenopathy, Splenomegaly OMIM:603552
Immunodeficiency 52
Lymphadenopathy, Splenomegaly OMIM:617514
Immunodeficiency, Common Variable, 2
Follicular hyperplasia, Lymphadenopathy, Splenomegaly OMIM:240500
Leukocyte Adhesion Deficiency, Type Iii
Hepatosplenomegaly, Abnormality of the lymph nodes, Splenomegaly OMIM:612840
Autoimmune Lymphoproliferative Syndrome, Type Iii
Generalized lymphadenopathy, Follicular hyperplasia, Splenomegaly, Mediastinal lymphadenopathy, H... OMIM:615559
Immunodeficiency, X-Linked, With Magnesium Defect, Epstein-Barr Virus Infection, And Neoplasia
Mediastinal lymphadenopathy, Lymphadenopathy, Splenomegaly OMIM:300853
Immunodeficiency 27A
Enlarged mesenteric lymph node, Hepatosplenomegaly, Lymphadenopathy, Splenomegaly OMIM:209950
Severe Combined Immunodeficiency Due To Adenosine Deaminase Deficiency
Absent tonsils, Absence of lymph node germinal center ORPHA:277
Pseudomyxoma Peritonei
Lymphadenopathy ORPHA:26790
Familial Cold Autoinflammatory Syndrome 2
Lymphadenopathy, Splenomegaly OMIM:611762
Classic Mycosis Fungoides
Lymphadenopathy, Splenomegaly ORPHA:2584
Cold Agglutinin Disease
Lymphadenopathy, Splenomegaly ORPHA:56425
Schnitzler Syndrome
Lymphadenopathy, Splenomegaly ORPHA:37748
Indolent Systemic Mastocytosis
Lymphadenopathy, Splenomegaly ORPHA:98848
Middle Ear Neuroendocrine Tumor
Chronic noninfectious lymphadenopathy ORPHA:100084
Pleural Mesothelioma
Lymphadenopathy ORPHA:50251
Caspase 8 Deficiency
Lymphadenopathy, Splenomegaly OMIM:607271
Classic Hodgkin Lymphoma
Bone marrow hypocellularity, Lymphadenopathy, Splenomegaly ORPHA:391
Periodic Fever, Immunodeficiency, And Thrombocytopenia Syndrome
Lymphadenopathy, Splenomegaly OMIM:150550
Immunodeficiency, Common Variable, 1
Lymphadenopathy, Splenomegaly OMIM:607594
Autoinflammatory Syndrome, Familial, With Or Without Immunodeficiency
Lymphadenopathy, Splenomegaly OMIM:619375
Corticosteroid-Sensitive Aseptic Abscess Syndrome
Abnormality of the lymphatic system, Abnormality of the lymph nodes ORPHA:54251
Immunodeficiency 54
Lymphadenopathy, Splenomegaly OMIM:609981
Tularemia
Abnormal nasopharyngeal adenoid morphology, Mediastinal lymphadenopathy, Lymphadenopathy, Cervica... ORPHA:3392
Ras-Associated Autoimmune Leukoproliferative Disorder
Follicular hyperplasia, Splenomegaly OMIM:614470
Nephroblastoma
Lymphadenopathy ORPHA:654
Systemic-Onset Juvenile Idiopathic Arthritis
Lymphadenopathy, Splenomegaly ORPHA:85414
Immunodeficiency 10
Lymphadenopathy OMIM:612783
Lymphoproliferative Syndrome 2
Hepatosplenomegaly, Lymphadenopathy, Splenomegaly OMIM:615122
Congenital Toxoplasmosis
Lymphadenopathy ORPHA:858
Meige Disease
Lymph node hypoplasia, Absence of lymph node germinal center ORPHA:90186
Klatskin Tumor
Lymphadenopathy ORPHA:99978
Cinca Syndrome
Hepatosplenomegaly, Lymphadenopathy OMIM:607115
Immunodeficiency 71 With Inflammatory Disease And Congenital Thrombocytopenia
Lymphadenopathy OMIM:617718
Omenn Syndrome
Hypoplasia of the thymus, Lymphadenopathy, Splenomegaly OMIM:603554
Squamous Cell Carcinoma Of The Anal Canal
Lymphadenopathy ORPHA:424019
Thyroid Lymphoma
Lymphadenopathy ORPHA:97285
Rhabdoid Tumor
Lymphadenopathy ORPHA:69077
Proteasome-Associated Autoinflammatory Syndrome 4
Lymphadenopathy, Splenomegaly OMIM:619183
Griscelli Syndrome Type 2
Lymphadenopathy, Splenomegaly ORPHA:79477
Acquired Hypertrichosis Lanuginosa
Lymphadenopathy ORPHA:2221
Combined Immunodeficiency Due To Zap70 Deficiency
Lymphadenitis, Hepatosplenomegaly, Abnormality of the lymph nodes, Lymphadenopathy ORPHA:911
Pyogenic Arthritis-Pyoderma Gangrenosum-Acne Syndrome
Lymphadenopathy ORPHA:69126
Granulomatous Disease, Chronic, Autosomal Recessive, 5
Recurrent tonsillitis, Lymphadenitis, Splenomegaly, Hepatosplenomegaly, Lymphadenopathy OMIM:618935
Desmoplastic Small Round Cell Tumor
Mediastinal lymphadenopathy, Lymphadenopathy ORPHA:83469
Roifman Syndrome
Hepatosplenomegaly, Lymphadenopathy ORPHA:353298
Roifman Syndrome
Lymphadenopathy, Splenomegaly OMIM:616651
Deafness-Lymphedema-Leukemia Syndrome
Bone marrow hypocellularity, Lymphadenopathy, Splenomegaly ORPHA:3226
Autoimmune Lymphoproliferative Syndrome
Chronic noninfectious lymphadenopathy, Follicular hyperplasia, Splenomegaly OMIM:601859
Leishmaniasis
Lymphadenopathy, Splenomegaly ORPHA:507
Medullary Thyroid Carcinoma
Lymphadenopathy ORPHA:1332
Lymphoproliferative Syndrome, X-Linked, 1
Lymphadenopathy, Splenomegaly OMIM:308240
Boutonneuse Fever
Lymphadenopathy, Cervical lymphadenopathy ORPHA:83313
T-B+ Severe Combined Immunodeficiency Due To Gamma Chain Deficiency
Absent tonsils, Lymph node hypoplasia ORPHA:276
Melkersson-Rosenthal Syndrome
Lymphadenopathy ORPHA:2483
Autoimmune Lymphoproliferative Syndrome, Type Iia
Chronic noninfectious lymphadenopathy, Follicular hyperplasia, Lymphadenopathy, Splenomegaly OMIM:603909
Sézary Syndrome
Lymphadenopathy, Splenomegaly ORPHA:3162
Pancreatoblastoma
Abnormality of the lymph nodes ORPHA:677
Griscelli Syndrome
Bone marrow hypocellularity, Lymphadenopathy, Splenomegaly ORPHA:381
Kaposi Sarcoma
Abnormality of the spleen, Generalized lymphadenopathy ORPHA:33276
American Trypanosomiasis
Lymphadenopathy, Splenomegaly ORPHA:3386
Scrub Typhus
Lymphadenopathy, Splenomegaly ORPHA:83317
Cyclic Neutropenia
Recurrent tonsillitis, Lymphadenopathy, Cervical lymphadenopathy ORPHA:2686
Purine Nucleoside Phosphorylase Deficiency
Lymph node hypoplasia, Splenomegaly OMIM:613179
Autoimmune Lymphoproliferative Syndrome, Type V
Lymphadenopathy, Splenomegaly OMIM:616100
Pulmonary Non-Tuberculous Mycobacterial Infection
Lymphadenopathy ORPHA:411703
Primary Myelofibrosis
Hepatosplenomegaly, Lymphadenopathy, Splenomegaly ORPHA:824
Anaplastic Thyroid Carcinoma
Lymphadenopathy ORPHA:142
Thymic Neuroendocrine Tumor
Mediastinal lymphadenopathy, Chronic noninfectious lymphadenopathy, Neoplasm of the thymus ORPHA:97289
Cutaneous Neuroendocrine Carcinoma
Chronic noninfectious lymphadenopathy ORPHA:79140
Combined Immunodeficiency Due To Crac Channel Dysfunction
Lymphadenopathy, Splenomegaly ORPHA:169090
Agammaglobulinemia, X-Linked
Lymph node hypoplasia OMIM:300755
Lymphoproliferative Syndrome 1
Lymphadenopathy, Splenomegaly OMIM:613011
Omenn Syndrome
Lymphadenopathy, Splenomegaly ORPHA:39041
Cinca Syndrome
Lymphadenopathy, Splenomegaly ORPHA:1451
Felty Syndrome
Bone marrow hypocellularity, Lymphadenopathy, Splenomegaly ORPHA:47612
Immunodeficiency With Hyper-Igm, Type 1
Absence of lymph node germinal center, Enlarged tonsils, Splenomegaly OMIM:308230
Gamma-Heavy Chain Disease
Lymphadenopathy, Splenomegaly ORPHA:100026
Niemann-Pick Disease, Type A
Lymphadenopathy, Splenomegaly OMIM:257200
Aggressive Systemic Mastocytosis
Hepatosplenomegaly, Hypersplenism, Lymphadenopathy ORPHA:98850
Adult-Onset Still Disease
Bone marrow hypocellularity, Generalized lymphadenopathy, Splenomegaly ORPHA:829
Castleman Disease
Mediastinal lymphadenopathy, Generalized lymphadenopathy, Follicular hyperplasia, Lymphadenopathy ORPHA:160
T-B+ Severe Combined Immunodeficiency Due To Il-7Ralpha Deficiency
Hepatosplenomegaly, Lymphadenopathy ORPHA:169154
Hypocomplementemic Urticarial Vasculitis
Lymphadenopathy, Splenomegaly ORPHA:36412
Hyperimmunoglobulinemia D With Periodic Fever
Lymphadenopathy ORPHA:343
Legionnaires Disease
Bone marrow hypocellularity, Lymphadenopathy, Splenomegaly ORPHA:549
Thymoma
Neoplasm of the thymus, Lymphadenopathy ORPHA:99867
Immunodeficiency 41 With Lymphoproliferation And Autoimmunity
Hepatosplenomegaly, Enlarged tonsils, Lymphadenopathy OMIM:606367
Mixed Connective Tissue Disease
Mediastinal lymphadenopathy, Lymphadenopathy, Splenomegaly ORPHA:809
Lassa Fever
Lymphadenopathy ORPHA:99824
Aregenerative Anemia
Bone marrow hypocellularity, Lymphadenopathy ORPHA:101096
Lig4 Syndrome
Lymphadenopathy ORPHA:99812
Immunodeficiency 73B With Defective Neutrophil Chemotaxis And Lymphopenia
Lymphadenitis, Hepatosplenomegaly, Generalized lymphadenopathy OMIM:618986
Granulomatous Disease, Chronic, Autosomal Recessive, 1
Lymphadenitis, Lymphadenopathy, Splenomegaly OMIM:233700
Granulomatous Disease, Chronic, Autosomal Recessive, 2
Lymphadenitis, Lymphadenopathy, Splenomegaly OMIM:233710
Hyper-Igd Syndrome
Lymphadenitis, Hepatosplenomegaly, Lymphadenopathy, Splenomegaly OMIM:260920
Immunodysregulation, Polyendocrinopathy, And Enteropathy, X-Linked
Lymphadenopathy OMIM:304790
Periodic Fever, Familial, Autosomal Dominant
Cervical lymphadenopathy OMIM:142680
Immunodeficiency, Common Variable, 8, With Autoimmunity
Generalized lymphadenopathy, Lymphadenopathy, Splenomegaly OMIM:614700
Malt Lymphoma
Mediastinal lymphadenopathy, Lymphadenopathy ORPHA:52417
Granulomatous Disease, Chronic, Autosomal Recessive, 4
Lymphadenitis, Lymphadenopathy, Splenomegaly OMIM:233690
Granulomatous Disease, Chronic, X-Linked
Lymphadenitis, Lymphadenopathy, Splenomegaly OMIM:306400
Pulmonary Capillary Hemangiomatosis
Mediastinal lymphadenopathy, Lymphadenopathy ORPHA:199241
Autoinflammation, Panniculitis, And Dermatosis Syndrome
Lymphadenopathy OMIM:617099
Acute Monoblastic/Monocytic Leukemia
Cervical lymphadenopathy ORPHA:514
Proteasome-Associated Autoinflammatory Syndrome 3
Lymphadenopathy, Splenomegaly OMIM:617591
Mevalonic Aciduria
Hepatosplenomegaly, Fluctuating splenomegaly, Lymphadenopathy OMIM:610377
Carney Triad
Mediastinal lymphadenopathy, Lymphadenopathy ORPHA:139411
Familial Hemophagocytic Lymphohistiocytosis
Lymphadenopathy, Splenomegaly ORPHA:540
Acute Interstitial Pneumonia
Lymphadenopathy ORPHA:79126
Sting-Associated Vasculopathy, Infantile-Onset
Paratracheal lymphadenopathy, Follicular hyperplasia OMIM:615934
Carcinoid Syndrome
Chronic noninfectious lymphadenopathy ORPHA:100093
Familial Pancreatic Carcinoma
Hepatosplenomegaly, Lymphadenopathy ORPHA:1333
Drug Rash With Eosinophilia And Systemic Symptoms
Lymphadenopathy ORPHA:139402
Acute Promyelocytic Leukemia
Lymphadenopathy ORPHA:520
Pediatric Systemic Lupus Erythematosus
Lymphadenopathy ORPHA:93552
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Positive, Nk Cell-Negative
Absent peripheral lymph nodes in presence of infection OMIM:600802
Hemophagocytic Lymphohistiocytosis, Familial, 2
Hepatosplenomegaly, Lymphadenopathy, Splenomegaly OMIM:603553
Hemophagocytic Lymphohistiocytosis, Familial, 1
Lymphadenopathy, Splenomegaly OMIM:267700
Chediak-Higashi Syndrome
Lymphadenopathy, Splenomegaly OMIM:214500
Graft Versus Host Disease
Hepatosplenomegaly, Lymphadenopathy ORPHA:39812
Lymphatic Filariasis
Lymphadenitis, Abnormality of the lymphatic system, Lymphangiectasis, Lymphadenopathy ORPHA:2035
Hepatic Veno-Occlusive Disease-Immunodeficiency Syndrome
Absence of lymph node germinal center, Hepatosplenomegaly ORPHA:79124
Cherubism
Submandibular lymph node enlargement OMIM:118400
Kikuchi-Fujimoto Disease
Generalized lymphadenopathy, Splenomegaly, Abnormality of the lymph nodes, Lymphadenopathy, Cervi... ORPHA:50918
Neuroendocrine Tumor Of The Colon
Chronic noninfectious lymphadenopathy ORPHA:100080
Histiocytosis-Lymphadenopathy Plus Syndrome
Splenomegaly, Hepatosplenomegaly, Lymphadenopathy, Cervical lymphadenopathy OMIM:602782
Farber Disease
Hepatosplenomegaly, Lymphadenopathy ORPHA:333
Common Variable Immunodeficiency
Lymphadenopathy, Splenomegaly ORPHA:1572
Waldenström Macroglobulinemia
Lymphadenopathy, Splenomegaly ORPHA:33226
Poems Syndrome
Lymphadenopathy ORPHA:2905
Systemic Mastocytosis With Associated Hematologic Neoplasm
Lymphadenopathy, Splenomegaly ORPHA:98849
Tangier Disease
Chronic noninfectious lymphadenopathy, Orange discolored tonsils, Hepatosplenomegaly ORPHA:31150
H Syndrome
Hepatosplenomegaly, Lymphadenopathy ORPHA:168569
Adenocarcinoma Of The Anal Canal
Lymphadenopathy ORPHA:424016
Gallbladder Neuroendocrine Tumor
Chronic noninfectious lymphadenopathy ORPHA:100086
Rheumatoid Factor-Negative Polyarticular Juvenile Idiopathic Arthritis
Hepatosplenomegaly, Lymphadenopathy ORPHA:85408
Neuroendocrine Tumor Of The Rectum
Chronic noninfectious lymphadenopathy ORPHA:100081
Neuroendocrine Tumor Of Anal Canal
Chronic noninfectious lymphadenopathy ORPHA:100082
Q Fever
Hepatosplenomegaly, Lymphadenopathy, Splenomegaly ORPHA:781
Vasculitis, Autoinflammation, Immunodeficiency, And Hematologic Defects Syndrome
Hepatosplenomegaly, Bone marrow hypocellularity, Lymphadenopathy, Splenomegaly OMIM:615688
Selective Igm Deficiency
Lymphadenitis, Lymphadenopathy ORPHA:331235
Multiple Myeloma
Lymphadenopathy, Splenomegaly ORPHA:29073
Lymphangioleiomyomatosis
Pulmonary lymphangiomyomatosis, Abnormality of the lymphatic system, Lymphadenopathy ORPHA:538
Spondyloenchondrodysplasia With Immune Dysregulation
Lymphadenopathy OMIM:607944
Hennekam Syndrome
Lymphangioma, Pulmonary lymphangiectasia, Lymphadenopathy, Splenomegaly ORPHA:2136
X-Linked Lymphoproliferative Disease
Enlarged tonsils, Splenomegaly, Hepatosplenomegaly, Bone marrow hypocellularity, Lymphadenopathy,... ORPHA:2442
Autoimmune Lymphoproliferative Syndrome
Chronic noninfectious lymphadenopathy, Hypersplenism, Splenomegaly, Bone marrow hypocellularity, ... ORPHA:3261
Immune Dysregulation-Polyendocrinopathy-Enteropathy-X-Linked Syndrome
Lymphadenopathy, Splenomegaly ORPHA:37042
Chédiak-Higashi Syndrome
Hepatosplenomegaly, Lymphadenopathy, Splenomegaly ORPHA:167
Ileal Neuroendocrine Tumor
Lymphadenopathy ORPHA:100078
Jejunal Neuroendocrine Tumor
Lymphadenopathy ORPHA:100077
Coccidioidomycosis
Mediastinal lymphadenopathy, Abnormality of the spleen, Lymphadenopathy ORPHA:228123
Tumor Necrosis Factor Receptor 1 Associated Periodic Syndrome
Lymphadenopathy, Splenomegaly ORPHA:32960
Chikungunya
Lymphadenopathy, Cervical lymphadenopathy ORPHA:324625
Familial Mediterranean Fever
Lymphadenopathy, Splenomegaly ORPHA:342
Duodenal Neuroendocrine Tumor
Lymphadenopathy ORPHA:100076
Malakoplakia
Follicular hyperplasia ORPHA:556
Igg4-Related Submandibular Gland Disease
Lymphadenopathy ORPHA:449432
Igg4-Related Kidney Disease
Lymphadenitis, Lymphadenopathy ORPHA:449395
Autosomal Recessive Malignant Osteopetrosis
Lymphadenopathy, Splenomegaly ORPHA:667
Brucellosis
Splenomegaly, Hypersplenism, Lymphadenopathy ORPHA:1304
Behçet Disease
Lymphadenopathy, Splenomegaly ORPHA:117
Sarcoidosis, Susceptibility To, 1
Mediastinal lymphadenopathy, Generalized lymphadenopathy, Splenomegaly OMIM:181000
Proteasome-Associated Autoinflammatory Syndrome 1
Lymphadenopathy, Splenomegaly OMIM:256040
Neuroendocrine Neoplasm Of Appendix
Chronic noninfectious lymphadenopathy ORPHA:100079
Primary Sjögren Syndrome
Lymphadenopathy ORPHA:289390
Sarcoidosis
Abnormality of the lymph nodes, Lymphadenopathy ORPHA:797
Igg4-Related Ophthalmic Disease
Lymphadenopathy ORPHA:449563
African Trypanosomiasis
Hepatosplenomegaly, Lymphadenopathy, Splenomegaly ORPHA:3385
Blau Syndrome
Lymphadenopathy, Splenomegaly ORPHA:90340
Leptospirosis
Lymphadenopathy ORPHA:509

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Rnpepl1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Rnpepl1.

No publications found that use IMPC mice or data for Rnpepl1.

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MGI Allele Allele Type Produced
Rnpepl1tm99124(L1L2_Bact_P) Targeting vectors
Rnpepl1em1(IMPC)Mbp Exon Deletion Mice, Tissue

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