Gene: Bzw2

Name
basic leucine zipper and W2 domains 2
MGI ID
MGI:1914162
Synonyms
1110001I24Rik HSPC028
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating alkaline phosphatase level Bzw2tm1b(KOMP)Mbp HOM postnatal 2.54×10-05
increased bone mineral content Bzw2tm1b(KOMP)Mbp HOM postnatal 1.75×10-07
increased body length Bzw2tm1b(KOMP)Mbp HOM postnatal 5.88×10-05
cardiovascular system phenotype Bzw2tm1b(KOMP)Mbp HOM postnatal 3.41×10-05
shortened RR interval Bzw2tm1b(KOMP)Mbp HOM postnatal 1.49×10-05
abnormal sleep behavior Bzw2tm1b(KOMP)Mbp HOM postnatal 8.34×10-05
decreased circulating glucose level Bzw2tm1b(KOMP)Mbp HOM postnatal 3.82×10-09
increased lean body mass Bzw2tm1b(KOMP)Mbp HOM postnatal 1.92×10-08
abnormal bone structure Bzw2tm1b(KOMP)Mbp HOM postnatal 1.66×10-05
increased circulating glucose level Bzw2tm1b(KOMP)Mbp HOM postnatal 3.82×10-09
decreased total body fat amount Bzw2tm1b(KOMP)Mbp HOM postnatal 1.56×10-05
increased bone mineral density Bzw2tm1b(KOMP)Mbp HOM postnatal 1.18×10-08

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (1/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (2/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (1/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485) N/A
Ear 1  (1/485) N/A
Embryo 1  (1/485)  (1/2)  Wholemount images
Eye 1  (1/485)  (1/2) N/A
Foot 1  (1/485)  (1/2) N/A
Forebrain 1  (1/485) N/A
Forelimb 1  (1/485)  (1/2) N/A
Hand 1  (1/485) N/A
Head 1  (5/485)  (1/2) N/A
Heart 1  (1/485) N/A
Hindbrain 1  (6/485) N/A
Hindlimb 1  (1/485)  (1/2) N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) N/A
Mandibular process 1  (1/485)  (1/2) N/A
Maxillary process 1  (1/485)  (1/2) N/A
Midbrain 1  (1/485) N/A
Oral cavity 1  (1/485) N/A
Skin 1  (1/485) N/A
Tail 1  (1/485)  (1/2) N/A
Tail somite 1  (1/485) N/A
Umbilical artery embryonic part 1  (1/47)  (1/1) N/A
Umbilical vein embryonic part 1  (1/47)  (1/1) N/A

 Associated Images

Sleep Wake: Wake state (bmp file)
16 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
16 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Electroretinography: Rod waveform (pdf format)
4 Images
Electroretinography: Cone waveform (pdf format)
4 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Combined SHIRPA and Dysmorphology
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Bzw2tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Bzw2tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice

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