Gene: Dph6

Name
diphthamine biosynthesis 6
MGI ID
MGI:1913882
Synonyms
Atpbd4 Diphthine ammonia ligase 5730421E18Rik
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N/A
Other links
Expression & images (0) Disease models (0) Order (1)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased Ly6C-positive mature NK cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased effector memory CD4-positive, alpha-beta T cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased CD5-positive gamma-delta T cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
decreased erythrocyte cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 4.31×10-07
increased dendritic cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
decreased body length Dph6tm1a(KOMP)Wtsi HOM postnatal 1.41×10-05
increased granulocyte number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
abnormal coat/hair pigmentation Dph6tm1a(KOMP)Wtsi HOM postnatal 2.62×10-05
decreased CD8-positive, naive alpha-beta T cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased effector memory CD8-positive, alpha-beta T cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 9.00×10-07
decreased hemoglobin content Dph6tm1a(KOMP)Wtsi HOM postnatal 4.19×10-05
increased marginal zone B cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
decreased CD8-positive, alpha-beta T cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
vertebral transformation Dph6tm1a(KOMP)Wtsi HOM postnatal 1.15×10-06
decreased mature B cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased caudal vertebrae number Dph6tm1a(KOMP)Wtsi HOM postnatal 4.20×10-06
increased gamma-delta T cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
decreased NK T cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased CD11b-low dendritic cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased plasmacytoid dendritic cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased CD4-positive, alpha beta T cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased effector memory T-helper cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased monocyte cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased Ly6C low monocyte number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased memory-marker gamma-delta T cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased plasma cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased KLRG1-positive T-helper cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
decreased effector memory CD8-positive, alpha-beta T cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
increased memory-marker CD4-negative NK T cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00
decreased hematocrit Dph6tm1a(KOMP)Wtsi HOM postnatal 1.71×10-05
decreased T-helper cell number Dph6tm1a(KOMP)Wtsi HOM postnatal 0.00

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 Expression

Expression data not available

 Associated Images

Spleen Immunophenotyping: Images associated with FACS analysis
171 Images
DSS Histology
8 Images
Anti-nuclear antibody assay
6 Images
Mesenteric Lymph Node Immunophenotyping: Images associated with FACS analysis
102 Images
X-ray: XRay Images Dorso Ventral
45 Images
X-ray: XRay Images Lateral Orientation
28 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
17 Images
Eye Morphology: Images Ophthalmoscopy
3 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Dph6tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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