Xpo5 | exportin 5
Physiological systems
22 / 24 physiological systems tested
11 Significantly impacted by the knock-out
Reproductive system Immune system Integument Endocrine/exocrine gland Embryo Growth/size/body region Nervous system Vision/eye Hematopoietic system Cardiovascular system Mortality/aging
11 No significant impact
2 Not tested
Data collections
Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal ovary morphology | 1 supporting dataset | Xpo5em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
enlarged ovary | 1 supporting dataset | Xpo5em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
spina bifida | 1 supporting dataset | Xpo5em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
abnormal spleen morphology | 1 supporting dataset | Xpo5em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
prenatal lethality prior to heart atrial septation | 1 supporting dataset | Xpo5em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
microphthalmia | 1 supporting dataset | Xpo5em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
embryonic lethality prior to organogenesis | 1 supporting dataset | Xpo5em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
hemorrhage | 1 supporting dataset | Xpo5em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Xpo5em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
enlarged spleen | 1 supporting dataset | Xpo5em1(IMPC)Mbp | heterozygote | Late adult | N/A * |
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External links
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Xpo5em1(IMPC)Mbp | Exon Deletion | | mouse |
Xpo5tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
Xpo5tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |