Gene: Exosc3

Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal heart morphology Exosc3tm1.1(KOMP)Vlcg HET postnatal 0.00
embryonic lethality prior to organogenesis Exosc3tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
embryonic lethality prior to tooth bud stage Exosc3tm1.1(KOMP)Vlcg HOM embryonic day 12.5 0.00
preweaning lethality, incomplete penetrance Exosc3tm1.1(KOMP)Vlcg HOM n/a 0.00
enlarged heart Exosc3tm1.1(KOMP)Vlcg HET postnatal 0.00

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 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 1  (1/51) N/A
Brain 1  (6/485)  (1/1) N/A
Central nervous system ganglion 1  (1/51) N/A
Dorsal root ganglion 1  (1/47) N/A
Ear 1  (1/485) N/A
Embryo 1  (1/485)  (1/1) N/A
Eye 1  (1/485) N/A
Foot 1  (1/485) N/A
Forebrain 1  (1/485)  (1/1) N/A
Forelimb 1  (1/485) N/A
Fronto-nasal process 1  (1/48) N/A
Gut 1  (1/50) N/A
Hand 1  (1/485) N/A
Head 1  (5/485) N/A
Head mesenchyme 1  (1/47) N/A
Heart 1  (1/485) N/A
Hindbrain 1  (6/485) N/A
Hindlimb 1  (1/485) N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) N/A
Mandibular process 1  (1/485) N/A
Maxillary process 1  (1/485) N/A
Midbrain 1  (1/485) N/A
Nasal septum 1  (1/47) N/A
Nose 1  (1/51) N/A
Notochord 1  (1/47) N/A
Oral cavity 1  (1/485) N/A
Skeleton 1  (1/51) N/A
Skin 1  (1/485) N/A
Spinal cord 1  (1/50) N/A
Tail 1  (1/485) N/A
Tail somite 1  (1/485) N/A
Trunk mesenchyme 1  (1/47) N/A
Vibrissa 1  (1/47) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
40 Images
X-ray: XRay Images Lateral Orientation
20 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Exosc3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Exosc3tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Exosc3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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