Gene: Atp6v1c1

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Name
ATPase, H+ transporting, lysosomal V1 subunit C1
MGI ID
MGI:1913585
Synonyms
1700025B18Rik
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to organogenesis Atp6v1c1tm1b(NCOM)Mfgc HOM E9.5 0.00
hypoactivity Atp6v1c1tm1b(NCOM)Mfgc HET Early adult 2.53×10-06
decreased prepulse inhibition Atp6v1c1tm1b(NCOM)Mfgc HET Early adult 1.03×10-08
embryonic lethality prior to tooth bud stage Atp6v1c1tm1b(NCOM)Mfgc HOM E12.5 0.00
preweaning lethality, complete penetrance Atp6v1c1tm1b(NCOM)Mfgc HOM Early adult 0.00
increased mean corpuscular volume Atp6v1c1tm1b(NCOM)Mfgc HET Early adult 1.86×10-08

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 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61) N/A
Brain 4  (6/504)  (2/4) N/A
Central nervous system ganglion 2  (1/70)  (2/2) N/A
Ear 4  (1/504)  (2/4) N/A
Embryo 4  (1/505)  (4/4) N/A
Eye 4  (1/504)  (2/4) N/A
Foot 4  (1/504)  (2/4) N/A
Forebrain 4  (1/504)  (2/4) N/A
Forelimb 4  (1/504)  (2/4) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 4  (1/503)  (2/4) N/A
Head 4  (5/504)  (2/4) N/A
Heart 4  (1/504)  (2/4) N/A
Hindbrain 4  (6/504)  (2/4) N/A
Hindlimb 4  (1/503)  (2/4) N/A
Liver 4  (1/504)  (2/4) N/A
Lung 4  (1/500)  (2/4) N/A
Mandibular process 4  (1/504)  (2/4) N/A
Maxillary process 4  (1/504)  (2/4) N/A
Midbrain 4  (1/504)  (2/4) N/A
Nose 2  (1/70)  (2/2) N/A
Oral cavity 4  (1/504)  (2/4) N/A
2  (7/37)  (2/2) N/A
Skeleton 2  (1/70)  (2/2) N/A
Skin 4  (1/504)  (2/4) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Tail 4  (1/504)  (2/4) N/A
Tail somite 4  (1/504)  (2/4) N/A
Trachea 2  (1/56)  (2/2) N/A
Urinary system 2  (1/56)  (2/2) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
16 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Eye Morphology: Images Slit Lamp
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Atp6v1c1tm1b(NCOM)Mfgc Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Atp6v1c1tm1a(NCOM)Mfgc KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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