Gene Summary
IMPC Data Collections
- Body Weight Measurements
- No Embryo Imaging Data
- Viability Data
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases associated to Tm4sf20 by orthology or direct annotation.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Specific Language Impairment 5 | OMIM:615432 |
The table below shows human diseases predicted to be associated to Tm4sf20 by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Cephalin Lipidosis | Abnormality of the spleen | OMIM:212800 | |
Immunodeficiency 80 With Or Without Congenital Cardiomyopathy | Impaired lymphocyte transformation with phytohemagglutinin, T lymphocytopenia, B lymphocytopenia,... | OMIM:619313 | |
Lissencephaly Syndrome, Norman-Roberts Type | Hypoplastic spleen | ORPHA:89844 | |
Stormorken Syndrome | Howell-Jolly bodies, Asplenia, Anemia, Hypoplastic spleen, Thrombocytopenia | OMIM:185070 | |
Gracile Bone Dysplasia | Asplenia, Hypoplastic spleen | OMIM:602361 | |
Mirage Syndrome | Anemia, Leukopenia, Hypoplastic spleen, Lymphopenia, Thrombocytopenia | OMIM:617053 | |
Pearson Syndrome | Hepatomegaly, Reticulocytosis, Pancytopenia, Pancreatic fibrosis, Thrombocytopenia, Splenomegaly,... | ORPHA:699 | |
Microphthalmia, Syndromic 9 | Hypoplastic spleen, Multilobulated spleen | OMIM:601186 | |
Specific Language Impairment 5 | OMIM:615432 |
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MGI Allele | Allele Type | Produced |
---|---|---|
Tm4sf20tm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | Targeting vectors, ES Cells |
Tm4sf20em1(IMPC)Bay | Exon Deletion | Mice |
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