Gene Summary

Name:
trafficking protein particle complex 2
Synonyms:
1110066L09Rik,  Sedl,  MIP-2A,  TRS20,  1810064C02Rik

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
decreased bronchoconstrictive response Trappc2tm1.1(KOMP)Vlcg HEM Early adult 3.94×10-05
hydrometra Trappc2tm1.1(KOMP)Vlcg HOM Early adult 0.00
increased pulmonary ventilation Trappc2tm1.1(KOMP)Vlcg HEM Early adult 2.52×10-05
decreased pulmonary ventilation Trappc2tm1.1(KOMP)Vlcg HEM Early adult 1.02×10-05
decreased pulmonary ventilation Trappc2tm1.1(KOMP)Vlcg HOM Early adult 6.51×10-06
decreased body length Trappc2tm1.1(KOMP)Vlcg HEM Early adult 2.43×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

An assay measuring the expression of lacZ shows the tissue where the gene is expressed.

Anatomy Images Zygosity Mutant Expr
Adrenal gland  Section images hemizygote 100% (1 of 1)
Adrenal gland  Section images heterozygote 100% (1 of 1)
Aorta  Section images hemizygote 100% (1 of 1)
Blood  Section images hemizygote 100% (1 of 1)
Blood  Section images heterozygote 100% (1 of 1)
Bone marrow  Section images hemizygote 100% (1 of 1)
Bone marrow  Section images heterozygote 100% (1 of 1)
Brown adipose tissue  Section images hemizygote 100% (1 of 1)
Brown adipose tissue  Section images heterozygote 100% (1 of 1)
Cecum  Section images hemizygote 100% (1 of 1)
Cerebellum  Section images hemizygote 100% (1 of 1)
Cerebellum  Section images heterozygote 100% (1 of 1)
Colon  Section images hemizygote 100% (1 of 1)
Colon  Section images heterozygote 100% (1 of 1)
Duodenum  Section images hemizygote 100% (1 of 1)
Duodenum  Section images heterozygote 100% (1 of 1)
Epididymis  Section images hemizygote 100% (1 of 1)
Esophagus  Section images hemizygote 100% (1 of 1)
Esophagus  Section images heterozygote 100% (1 of 1)
Eye  Section images hemizygote 100% (1 of 1)
Eye  Section images heterozygote 100% (1 of 1)
Harderian gland  Section images heterozygote 100% (1 of 1)
Ileum  Section images hemizygote 100% (1 of 1)
Ileum  Section images heterozygote 100% (1 of 1)
Jejunum  Section images hemizygote 100% (1 of 1)
Kidney  Section images hemizygote 100% (1 of 1)
Kidney  Section images heterozygote 100% (1 of 1)
Lung  Section images hemizygote 100% (1 of 1)
Lung  Section images heterozygote 100% (1 of 1)
Mesenteric adipose tissue  Section images hemizygote 100% (1 of 1)
Midbrain  Section images hemizygote 100% (1 of 1)
Midbrain  Section images heterozygote 100% (1 of 1)
Olfactory lobe  Section images hemizygote 100% (1 of 1)
Olfactory lobe  Section images heterozygote 100% (1 of 1)
Oviduct  Section images heterozygote 100% (1 of 1)
Pancreas  Section images hemizygote 100% (1 of 1)
Parathyroid gland  Section images hemizygote 100% (1 of 1)
Parotid gland  Section images hemizygote 100% (1 of 1)
Penis  Section images hemizygote 100% (1 of 1)
Pituitary gland  Section images hemizygote 100% (1 of 1)
Pituitary gland  Section images heterozygote 100% (1 of 1)
Prostate gland  Section images hemizygote 100% (1 of 1)
Quadriceps  Section images hemizygote 100% (1 of 1)
Skin  Section images hemizygote 100% (1 of 1)
Skin  Section images heterozygote 100% (1 of 1)
Spinal cord  Section images hemizygote 100% (1 of 1)
Spinal cord  Section images heterozygote 100% (1 of 1)
Spleen  Section images hemizygote 100% (1 of 1)
Stomach  Section images hemizygote 100% (1 of 1)
Stomach  Section images heterozygote 100% (1 of 1)
Sublingual gland  Section images hemizygote 100% (1 of 1)
Submandibular gland  Section images hemizygote 100% (1 of 1)
Testis  Section images hemizygote 100% (1 of 1)
Thymus  Section images hemizygote 100% (1 of 1)
Thymus  Section images heterozygote 100% (1 of 1)
Thyroid gland  Section images hemizygote 100% (1 of 1)
Tongue  Section images hemizygote 100% (1 of 1)
Tongue  Section images heterozygote 100% (1 of 1)
Trachea  Section images heterozygote 100% (1 of 1)
Trigeminal V nerve  Section images hemizygote 100% (1 of 1)
Trigeminal V nerve  Section images heterozygote 100% (1 of 1)
Urinary bladder  Section images hemizygote 100% (1 of 1)
Urinary bladder  Section images heterozygote 100% (1 of 1)
Uterus  Section images heterozygote 100% (1 of 1)
Vagina  Section images heterozygote 100% (1 of 1)
Vas deferens  Section images hemizygote 100% (1 of 1)
Vesicular gland  Section images hemizygote 100% (1 of 1)
Aorta N/A heterozygote Not available
Brain N/A hemizygote 100% (1 of 1)
Brain N/A heterozygote 100% (1 of 1)
Brainstem N/A hemizygote Not available
Brainstem N/A heterozygote Not available
Cartilage tissue N/A hemizygote Not available
Cartilage tissue N/A heterozygote Not available
Cecum N/A heterozygote Not available
Cerebral cortex N/A hemizygote Not available
Cerebral cortex N/A heterozygote Not available
Chest bone N/A hemizygote Not available
Chest bone N/A heterozygote Not available
Diaphragm N/A hemizygote 0.0% (0 of 1)
Diaphragm N/A heterozygote 0.0% (0 of 1)
Epididymis N/A heterozygote Not available
Gall bladder N/A hemizygote Not available
Gall bladder N/A heterozygote Not available
Gonadal fat pad N/A hemizygote 0.0% (0 of 1)
Gonadal fat pad N/A heterozygote 0.0% (0 of 1)
Harderian gland N/A hemizygote 0.0% (0 of 1)
Heart N/A hemizygote Not available
Heart N/A heterozygote Not available
Hindlimb N/A hemizygote Not available
Hindlimb N/A heterozygote Not available
Hippocampus N/A hemizygote Not available
Hippocampus N/A heterozygote Not available
Hypothalamus N/A hemizygote Not available
Hypothalamus N/A heterozygote Not available
Jejunum N/A heterozygote Not available
Large intestine N/A hemizygote 100% (1 of 1)
Large intestine N/A heterozygote 100% (1 of 1)
Liver N/A hemizygote 0.0% (0 of 1)
Liver N/A heterozygote 0.0% (0 of 1)
Lower urinary tract N/A hemizygote Not available
Lower urinary tract N/A heterozygote Not available
Lymph node N/A hemizygote Not available
Lymph node N/A heterozygote Not available
Mammary gland N/A hemizygote Not available
Mammary gland N/A heterozygote Not available
Mesenteric adipose tissue N/A heterozygote 0.0% (0 of 1)
Mesenteric lymph node N/A hemizygote 0.0% (0 of 1)
Mesenteric lymph node N/A heterozygote 0.0% (0 of 1)
Ovary N/A hemizygote Not available
Ovary N/A heterozygote Not available
Oviduct N/A hemizygote Not available
Pancreas N/A heterozygote 0.0% (0 of 1)
Parathyroid gland N/A heterozygote 0.0% (0 of 1)
Parotid gland N/A heterozygote 0.0% (0 of 1)
Penis N/A heterozygote Not available
Peripheral nervous system N/A hemizygote Not available
Peripheral nervous system N/A heterozygote Not available
Peyer's patch N/A hemizygote Not available
Peyer's patch N/A heterozygote Not available
Prostate gland N/A heterozygote Not available
Quadriceps N/A heterozygote 0.0% (0 of 1)
Sciatic nerve N/A hemizygote 0.0% (0 of 1)
Sciatic nerve N/A heterozygote 0.0% (0 of 1)
Skeletal muscle N/A hemizygote Not available
Skeletal muscle N/A heterozygote Not available
Small intestine N/A hemizygote 100% (1 of 1)
Small intestine N/A heterozygote 100% (1 of 1)
Spleen N/A heterozygote 0.0% (0 of 1)
Stomach pyloric region N/A hemizygote Not available
Stomach pyloric region N/A heterozygote Not available
Striatum N/A hemizygote Not available
Striatum N/A heterozygote Not available
Sublingual gland N/A heterozygote 0.0% (0 of 1)
Submandibular gland N/A heterozygote 0.0% (0 of 1)
Testis N/A heterozygote Not available
Thyroid gland N/A heterozygote 0.0% (0 of 1)
Trachea N/A hemizygote Not available
Uterus N/A hemizygote Not available
Vagina N/A hemizygote Not available
Vas deferens N/A heterozygote Not available
Vascular system N/A hemizygote Not available
Vascular system N/A heterozygote Not available
Vesicular gland N/A heterozygote Not available
White adipose tissue N/A hemizygote Not available
White adipose tissue N/A heterozygote Not available
No Embryo expression data was found for this gene.

Background staining occurs in wild type mice and embryos at an incidental rate.

Anatomy Background staining in controls (WT)
adrenal gland 0.0%
aorta 0.0%
blood
bone marrow
brain 0.0%
brainstem 0.0%
brown adipose tissue 0.0%
cartilage tissue 0.0%
cecum 0.0%
cerebellum 0.0%
cerebral cortex 0.0%
chest bone
colon
diaphragm 0.0%
duodenum 0.0%
epididymis Unavailable
esophagus 0.0%
eye 0.0%
gall bladder 0.0%
gonadal fat pad 0.0%
harderian gland
heart 0.0%
hindlimb 0.0%
hippocampus 0.0%
hypothalamus 0.0%
ileum 0.0%
jejunum
kidney 0.0%
large intestine 0.0%
liver 0.0%
lower urinary tract 0.0%
lung 0.0%
lymph node 0.0%
mammary gland 0.0%
mesenteric adipose tissue 0.0%
mesenteric lymph node
midbrain 0.0%
olfactory lobe 0.0%
ovary 0.0%
oviduct 0.0%
pancreas 0.0%
parathyroid gland 0.0%
parotid gland 0.0%
penis 0.0%
peripheral nervous system 0.0%
peyers patch 0.0%
pituitary gland 0.0%
prostate gland 0.0%
quadriceps 0.0%
sciatic nerve 0.0%
skeletal muscle 0.0%
skin 0.0%
small intestine 0.0%
spinal cord 0.0%
spleen 0.0%
stomach 0.0%
stomach pyloric region 0.0%
striatum 0.0%
sublingual gland 0.0%
submandibular gland 0.0%
testis 0.0%
thymus 0.0%
thyroid gland 0.0%
tongue 0.0%
trachea 0.0%
trigeminal v nerve 0.0%
urinary bladder
uterus 0.0%
vagina 0.0%
vas deferens Unavailable
vascular system 0.0%
vesicular gland Unavailable
white adipose tissue 0.0%
No Embryo expression data was found for this gene.

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Adult LacZ

LacZ Images Section

128 Images

X-ray

XRay Images Whole Body Dorso Ventral

10 Images

X-ray

XRay Images Skull Lateral Orientation

10 Images

X-ray

XRay Images Forepaw

10 Images

X-ray

XRay Images Skull Dorso Ventral Orientation

10 Images

X-ray

XRay Images Hind Leg and Hip

10 Images

X-ray

XRay Images Whole Body Lateral Orientation

10 Images

Human diseases caused by Trappc2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Trappc2 by orthology or direct annotation.

Disease Similarity of
phenotypes
Matching phenotypes Source
Spondyloepiphyseal Dysplasia Tarda, X-Linked
OMIM:313400
Spondyloepiphyseal Dysplasia Tarda
ORPHA:93284

The table below shows human diseases predicted to be associated to Trappc2 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Uterine Anomalies
Bicornuate uterus, Abnormality of the uterus OMIM:192000
Testicular Regression Syndrome
Abnormal male internal genitalia morphology, Aplasia/Hypoplasia of the testes, Hypoplasia of peni... ORPHA:983
46,Xy Sex Reversal 3
Gonadal dysgenesis, Clitoral hypertrophy, Penoscrotal hypospadias, Exaggerated rugosity of the la... OMIM:612965
Ovarian Dysgenesis 6
Hypoplasia of the uterus, Hypergonadotropic hypogonadism OMIM:618078
46,Xx Ovotesticular Difference Of Sex Development
Abnormal male internal genitalia morphology, Hypospadias, Hypoplasia of penis, Abnormal scrotal r... ORPHA:2138
Premature Ovarian Failure 3
Hypoplasia of the uterus OMIM:608996
46,Xy Sex Reversal 11
Abnormal internal genitalia, Aplasia of the uterus, Urogenital sinus anomaly, Vanishing testis, G... OMIM:273250
Obesity-Hypoventilation Syndrome
Hypoventilation OMIM:257500
46,Xy Sex Reversal 7
Streak ovary, Abnormal epididymis morphology, Gonadoblastoma, Hypoplasia of the fallopian tube, G... OMIM:233420
Athabaskan Brainstem Dysgenesis Syndrome
Central hypoventilation OMIM:601536
Leydig Cell Hypoplasia
Testicular gonadoblastoma, Hypospadias, Abnormal vas deferens morphology, Hypoplasia of the Leydi... ORPHA:755
Mayer-Rokitansky-Kuster-Hauser Syndrome
Abnormal female external genitalia morphology, Aplasia of the upper vagina, Aplasia of the vagina... OMIM:277000
Testicular Agenesis
Hypoplasia of the uterus, Abnormal vas deferens morphology, Urogenital sinus anomaly, Urethrovagi... ORPHA:325124
Diethylstilbestrol Syndrome
Hypoplasia of the uterus, Hypospadias, Abnormal testis morphology, Vaginal neoplasm, Abnormality ... ORPHA:1916
46,Xy Gonadal Dysgenesis-Motor And Sensory Neuropathy Syndrome
Gonadal dysgenesis, Abnormal female external genitalia morphology, Male hypogonadism, Abnormal va... ORPHA:168563
Ovarian Dysgenesis 2
Streak ovary, Hypoplasia of the uterus, Hypergonadotropic hypogonadism OMIM:300510
Premature Ovarian Failure 7
Gonadal dysgenesis, Clitoral hypertrophy, Hypoplasia of the uterus OMIM:612964
Complete Androgen Insensitivity Syndrome
Blind vagina, Female external genitalia in individual with 46,XY karyotype, Testicular neoplasm, ... ORPHA:99429
Partial Androgen Insensitivity Syndrome
Blind vagina, Clitoral hypertrophy, Hypospadias, Azoospermia, Aplasia of the uterus, Bifid scrotu... ORPHA:90797
Mullerian Aplasia And Hyperandrogenism
Abnormal external genitalia, Aplasia of the uterus, Aplasia of the fallopian tube, Aplasia of the... OMIM:158330
Vaginal Atresia
Transverse vaginal septum, Vaginal hematocele, Imperforate hymen, Bicornuate uterus, Cervicitis, ... ORPHA:65681
Hypogonadotropic Hypogonadism 12 With Or Without Anosmia
Hypoplasia of the ovary, Decreased testicular size, Micropenis, Cryptorchidism, Hypoplasia of the... OMIM:614841
Perrault Syndrome 6
Streak ovary, Hypoplasia of the uterus OMIM:617565
Premature Ovarian Failure 13
Hypoplasia of the uterus OMIM:617442
Central Hypoventilation Syndrome, Congenital, 3
Central hypoventilation OMIM:619483
Ullrich Congenital Muscular Dystrophy 2
Nocturnal hypoventilation OMIM:616470
Joubert Syndrome 17
Hyperventilation OMIM:614615
Hypogonadotropic Hypogonadism 8 With Or Without Anosmia
Hypoplasia of the uterus, Azoospermia, Decreased testicular size, Cryptorchidism, Micropenis, Hyp... OMIM:614837
Mitochondrial Complex I Deficiency, Nuclear Type 9
Hypoventilation OMIM:618232
Perrault Syndrome 3
Streak ovary, Hypoplasia of the uterus, Hypergonadotropic hypogonadism OMIM:614129
Renal And Mullerian Duct Hypoplasia
Aplasia of the uterus, Anteriorly displaced urethral meatus, Hydrocele testis OMIM:266810
46,Xx Sex Reversal 2
Hypoplasia of the uterus, Ovotestis, Azoospermia, Bifid scrotum, True hermaphroditism, Hypoplasia... OMIM:278850
Hypogonadotropic Hypogonadism 13 With Or Without Anosmia
Hypoplasia of the uterus, Hypogonadotropic hypogonadism OMIM:614842
Premature Ovarian Failure 6
Streak ovary, Hypoplasia of the uterus OMIM:612310
Premature Ovarian Failure 18
Hypoplasia of the ovary, Hypoplasia of the uterus OMIM:619203
Hydatidiform Mole
Enlarged uterus ORPHA:99927
Chronic Pneumonitis Of Infancy
Hyperventilation ORPHA:91359
Postpoliomyelitis Syndrome
Hypoventilation ORPHA:2942
Neurodevelopmental Disorder With Poor Language And Loss Of Hand Skills
Hyperventilation OMIM:617903
Pitt-Hopkins-Like Syndrome 2
Hyperventilation OMIM:614325
Perry Syndrome
Hypoventilation, Central hypoventilation OMIM:168605
Lumbar Syndrome
Hypospadias, Bifid scrotum, Bifid uterus, Ambiguous genitalia, Cryptorchidism, Micropenis, Hypopl... ORPHA:83628
Adult-Onset Cervical Dystonia, Dyt23 Type
Hyperventilation ORPHA:420492
Fructose-1,6-Bisphosphatase Deficiency
Hyperventilation OMIM:229700
Joubert Syndrome 8
Hyperventilation OMIM:612291
Autosomal Dominant Nocturnal Frontal Lobe Epilepsy
Hyperventilation ORPHA:98784
Childhood Absence Epilepsy
Hyperventilation ORPHA:64280
Pitt-Hopkins-Like Syndrome 1
Hyperventilation OMIM:610042
Congenital Adrenal Hyperplasia Due To 17-Alpha-Hydroxylase Deficiency
Blind vagina, Ambiguous genitalia, male, Female external genitalia in individual with 46,XY karyo... ORPHA:90793
Mayer-Rokitansky-K├╝ster-Hauser Syndrome
Endometriosis, Aplasia of the uterus, Ectopic ovary, Hypoplasia of the vagina, Aplasia of the ovary ORPHA:3109
Myasthenic Syndrome, Congenital, 20, Presynaptic
Hypoventilation OMIM:617143
Townes-Brocks Syndrome 2
Bifid uterus, Hypospadias, Rectovaginal fistula OMIM:617466
46,Xy Difference Of Sex Development-Adrenal Insufficiency Due To Cyp11A1 Deficiency
Female external genitalia in individual with 46,XY karyotype, Ambiguous genitalia, male, Clitoral... ORPHA:168558
Hypoparathyroidism, Sensorineural Deafness, And Renal Dysplasia Syndrome
Uterus didelphys, Septate vagina, Aplasia of the uterus, Aplasia of the vagina OMIM:146255
Inherited Isolated Adrenal Insufficiency Due To Partial Cyp11A1 Deficiency
Female external genitalia in individual with 46,XY karyotype, Ambiguous genitalia, male, Clitoral... ORPHA:289548
Holocarboxylase Synthetase Deficiency
Hyperventilation OMIM:253270
Adrenal Hyperplasia, Congenital, Due To Steroid 11-Beta-Hydroxylase Deficiency
Clitoral hypertrophy, Precocious puberty in males, Long penis, Decreased testicular size, Hypopla... OMIM:202010
Mitochondrial Complex Iii Deficiency, Nuclear Type 10
Hyperventilation OMIM:618775
Congenital Disorder Of Glycosylation, Type Iib
Hypoventilation, Hypoplastic female external genitalia OMIM:606056
Mitochondrial Complex Iv Deficiency, Nuclear Type 23
Hypoventilation OMIM:620275
Central Hypoventilation Syndrome, Congenital, 1
Hypoventilation, Nocturnal hypoventilation, Central hypoventilation OMIM:209880
Developmental And Epileptic Encephalopathy 2
Hyperventilation OMIM:300672
Muscular Dystrophy, Duchenne Type
Hypoventilation OMIM:310200
Encephalitis Lethargica
Hyperventilation ORPHA:83600
Rett Syndrome
Intermittent hyperventilation OMIM:312750
Lethal Omphalocele-Cleft Palate Syndrome
Bifid uterus ORPHA:2736
Oeis Complex
Epispadias, Ambiguous genitalia, male, Rectovaginal fistula, Vesicovaginal fistula, Labial hypopl... OMIM:258040
Prader-Willi Syndrome
Hypoventilation, External genital hypoplasia, Hypoplastic labia minora, Clitoral hypoplasia, Prec... OMIM:176270
Severe Neonatal Hypotonia-Seizures-Encephalopathy Syndrome Due To 5Q31.3 Microdeletion
Hypoventilation ORPHA:314655
Cntnap2-Related Developmental And Epileptic Encephalopathy
Intermittent hyperventilation ORPHA:163681
Hypoparathyroidism-Sensorineural Deafness-Renal Disease Syndrome
Uterus didelphys, Septate vagina, Aplasia of the uterus, Vaginal atresia ORPHA:2237
Cholera
Hyperventilation ORPHA:173
Bethlem Muscular Dystrophy
Hypoventilation ORPHA:610
Fructose-1,6-Bisphosphatase Deficiency
Intermittent hyperventilation ORPHA:348
Hypotonia, Hypoventilation, Impaired Intellectual Development, Dysautonomia, Epilepsy, And Eye Abnormalities
Hypoventilation OMIM:618493
Rabin-Pappas Syndrome
Hypoventilation OMIM:620155
Biotinidase Deficiency
Hyperventilation ORPHA:79241
Mogs-Cdg
Hypoventilation, External genital hypoplasia, Hydrocele testis ORPHA:79330
Intellectual Developmental Disorder, Autosomal Dominant 57
Hyperventilation OMIM:618050
Intellectual Developmental Disorder With Microcephaly And Pontine And Cerebellar Hypoplasia
Intermittent hyperventilation OMIM:300749
Classic Congenital Adrenal Hyperplasia Due To 21-Hydroxylase Deficiency
Clitoral hypertrophy, Premature pubarche, Precocious puberty in females, Long penis, Abnormal ext... ORPHA:90794
Synaptic Congenital Myasthenic Syndromes
Hypoventilation ORPHA:98915
Intellectual Developmental Disorder, Autosomal Dominant 54
Hyperventilation OMIM:617799
Infantile Hypotonia-Oculomotor Anomalies-Hyperkinetic Movements-Developmental Delay Syndrome
Hyperventilation ORPHA:522077
Spondylocostal Dysostosis With Anal Atresia And Urogenital Anomalies
Aplasia of the uterus, Absent external genitalia, Aplasia of the vagina OMIM:271520
Proximal Spinal Muscular Atrophy
Hypoventilation ORPHA:70
Pontocerebellar Hypoplasia Type 7
Gonadal dysgenesis, Clitoral hypertrophy, Abnormal scrotal rugation, Aplasia of the uterus, Micro... ORPHA:284339
Pitt-Hopkins Syndrome
Intermittent hyperventilation OMIM:610954
Meckel Syndrome 14
Ambiguous genitalia, Aplasia of the uterus OMIM:619879
Pitt-Hopkins Syndrome
Hyperventilation ORPHA:2896
Laminin Subunit Alpha 2-Related Congenital Muscular Dystrophy
Hypoventilation, Aspiration ORPHA:258
Thrombocytopenia-Absent Radius Syndrome
Aplasia of the uterus ORPHA:3320
Mitochondrial Dna-Associated Leigh Syndrome
Hyperventilation ORPHA:255210
Chromosome 17Q12 Deletion Syndrome
Aplasia of the vagina, Aplasia of the uterus, Unicornuate uterus, Ovarian cyst, Cryptorchidism OMIM:614527
Cocaine Intoxication
Hyperventilation ORPHA:90068
Phocomelia, Schinzel Type
Cryptorchidism, Aplasia of the uterus, Hypoplasia of penis ORPHA:2879
Charcot-Marie-Tooth Disease Type 4C
Hypoventilation ORPHA:99949
Craniofrontonasal Dysplasia-Poland Anomaly Syndrome
Bifid uterus, Abnormal reproductive system morphology ORPHA:1521
Microcephaly-Corpus Callosum Hypoplasia-Intellectual Disability-Facial Dysmorphism Syndrome
Aplasia of the uterus, Aplasia of the vagina ORPHA:457284
Fanconi Anemia, Complementation Group L
Aplasia of the uterus, Micropenis OMIM:614083
Cardiac-Urogenital Syndrome
Penoscrotal hypospadias, Aplasia of the uterus, Bifid scrotum, Unilateral cryptorchidism, Ambiguo... OMIM:618280
Exstrophy-Epispadias Complex
Penoscrotal transposition, Epispadias, Bifid penis, Bifid scrotum, Absent penis, Bifid uterus, Cy... ORPHA:322
Central Hypoventilation Syndrome, Congenital, 2, And Autonomic Dysfunction
Hypoventilation OMIM:619482
Limb-Mammary Syndrome
Aplasia of the uterus, Aplasia of the ovary ORPHA:69085
Mitochondrial Dna Depletion Syndrome 4A (Alpers Type)
Hypoventilation OMIM:203700
Thrombocytopenia-Absent Radius Syndrome
Aplasia of the uterus OMIM:274000
Acute Liver Failure
Hyperventilation ORPHA:90062
Rapid-Onset Childhood Obesity-Hypothalamic Dysfunction-Hypoventilation-Autonomic Dysregulation Syndrome
Hypoventilation, Central hypoventilation ORPHA:293987
Neurodevelopmental Disorder With Hypotonia And Speech Delay, With Or Without Seizures
Hypoventilation, Chordee, Phimosis OMIM:620455
Pura-Related Severe Neonatal Hypotonia-Seizures-Encephalopathy Syndrome
Precocious puberty, Uterine prolapse, Cryptorchidism, Hypoventilation ORPHA:438213
Ehlers-Danlos Syndrome, Vascular Type
Cervical insufficiency, Cryptorchidism, Uterine prolapse, Cystocele, Uterine rupture OMIM:130050
Wolf-Hirschhorn Syndrome
Precocious puberty, Cryptorchidism, Aplasia of the uterus, Hypospadias OMIM:194190
Coffin-Siris Syndrome 1
Clitoral hypertrophy, Cryptorchidism, Aplasia of the uterus, Hypospadias OMIM:135900
Autosomal Recessive Polycystic Kidney Disease
Hypoventilation ORPHA:731
Hydrolethalus Syndrome 1
Bifid uterus, Hypospadias, Abnormal vagina morphology OMIM:236680
Ulna And Fibula, Absence Of, With Severe Limb Deficiency
Hypospadias, Anteriorly displaced genitalia, Aplasia of the uterus, Small scrotum, Cryptorchidism OMIM:276820
Townes-Brocks Syndrome 1
Hypospadias, Rectovaginal fistula, Bifid scrotum, Rectoperineal fistula, Bifid uterus, Cryptorchi... OMIM:107480
Neu-Laxova Syndrome 1
Bifid uterus, Cryptorchidism OMIM:256520
Okamoto Syndrome
Bifid uterus ORPHA:2729
Loeys-Dietz Syndrome
Uterine rupture ORPHA:60030
Pallister-Killian Syndrome
Hyperventilation, Aplasia of the upper vagina, Hypospadias, Labial hypoplasia, Aplasia of the ute... OMIM:601803
Vascular Ehlers-Danlos Syndrome
Hypospadias, Uterine rupture, Uterine prolapse, Cystocele, Cryptorchidism ORPHA:286
Norrie Disease
Uterine rupture, Cryptorchidism ORPHA:649
Spondyloepiphyseal Dysplasia Tarda
ORPHA:93284
Spondyloepiphyseal Dysplasia Tarda, X-Linked
OMIM:313400

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Trappc2

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Trappc2.

No publications found that use IMPC mice or data for Trappc2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Trappc2tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Trappc2tm2e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells
Trappc2tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Trappc2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter