Gene: Sptssa

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Name
serine palmitoyltransferase, small subunit A
MGI ID
MGI:1913399
Synonyms
1110002B05Rik
Embryo viewer
N/A
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to organogenesis Sptssatm1b(KOMP)Wtsi HOM   E9.5 0.00
increased circulating calcium level Sptssatm1b(KOMP)Wtsi HET Early adult 9.45×10-05
decreased circulating glucose level Sptssatm1b(KOMP)Wtsi HET   Early adult 1.99×10-06
increased circulating sodium level Sptssatm1b(KOMP)Wtsi HET   Early adult 2.83×10-05
embryonic lethality prior to tooth bud stage Sptssatm1b(KOMP)Wtsi HOM   E12.5 0.00
preweaning lethality, complete penetrance Sptssatm1b(KOMP)Wtsi HOM   Early adult 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590)  (2/2)  Section images
Brain 2 No  (3/590)  Section images
Brainstem 2 No  (2/590)  (1/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590) N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No  (1/590)  (2/2)  Section images
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590) N/A
Kidney 2 No  (20/590)  (2/2)  Section images
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/590) N/A
Ovary 2 No  (1/590) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/590) N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590) N/A
Spleen 2 No  (2/590)  (2/2)  Section images
Stomach 2 No  (13/590) N/A
Striatum 2 No  (3/590) N/A
Submandibular gland 2 No  (2/132)  (1/2)  Section images
Testis 2 No  (5/590) N/A
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/590) N/A
Trachea 2 No  (2/590) N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/506) N/A
Dorsal root ganglion 1  (1/61) N/A
Ear 1  (1/506) N/A
Embryo 1  (1/507) N/A
Eye 1  (1/506) N/A
Foot 1  (1/506) N/A
Forebrain 1  (1/506) N/A
Forelimb 1  (1/506) N/A
Fronto-nasal process 1  (1/62) N/A
Hand 1  (1/506) N/A
Head 1  (5/506) N/A
Heart 1  (1/506) N/A
Hindbrain 1  (6/506) N/A
Hindlimb 1  (1/506) N/A
Liver 1  (1/504) N/A
Lung 1  (1/504) N/A
Mandibular process 1  (1/506) N/A
Maxillary process 1  (1/506) N/A
Midbrain 1  (1/506) N/A
Nose 1  (1/76) N/A
Oral cavity 1  (1/504) N/A
Skin 1  (1/506) N/A
Spinal cord 1  (1/73) N/A
Tail 1  (1/506) N/A
Tail somite 1  (1/506) N/A

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
12 Images
X-ray: XRay Images Whole Body Dorso Ventral
12 Images
X-ray: XRay Images Forepaw
12 Images
Combined SHIRPA and Dysmorphology
3 Images
Eye Morphology: Images Ophthalmoscopy
3 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
Original Image
Adult LacZ: LacZ Images Section
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
12 Images
Sleep Wake: Wake state (bmp file)
1 Images
Eye Morphology: Images Slit Lamp
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Sptssatm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Sptssatm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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