Gene Summary

Name:
ubiquitin-conjugating enzyme E2D 3
Synonyms:
9430029A22Rik,  1100001F19Rik

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
decreased bone mineral content Ube2d3tm1b(EUCOMM)Hmgu HET Early adult 1.16×10-08
decreased lean body mass Ube2d3tm1b(EUCOMM)Hmgu HET Early adult 2.43×10-05
decreased bone mineral density Ube2d3tm1b(EUCOMM)Hmgu HET Early adult 3.85×10-05
decreased locomotor activity Ube2d3tm1b(EUCOMM)Hmgu HET   Early adult 7.61×10-06
abnormal retina morphology Ube2d3tm1b(EUCOMM)Hmgu HET   Early adult 5.37×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Ube2d3 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Ube2d3

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Ube2d3.

No publications found that use IMPC mice or data for Ube2d3.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Ube2d3tm1e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells
Ube2d3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ube2d3tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (with selection cassette) Mice

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