Ndufb5 | NADH:ubiquinone oxidoreductase subunit B5

GeneMGI:1913296Synonyms: 0610007D05Rik

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Embryo Growth/size/body region Limbs/digits/tail Nervous system Mortality/aging Cardiovascular system

11 No significant impact

7 Not tested

Gene metrics:13Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal neural tube morphology1 supporting datasetNdufb5em1(IMPC)BayhomozygoteE9.5N/A * 
abnormal embryo turning1 supporting datasetNdufb5em1(IMPC)BayhomozygoteE9.5N/A * 
abnormal embryo size1 supporting datasetNdufb5em1(IMPC)BayhomozygoteE9.5N/A * 
abnormal allantois morphology1 supporting datasetNdufb5em1(IMPC)BayhomozygoteE9.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsNdufb5em1(IMPC)BayhomozygoteEarly adultN/A * 
abnormal tail bud morphology1 supporting datasetNdufb5em1(IMPC)BayhomozygoteE9.5N/A * 
abnormal heart morphology1 supporting datasetNdufb5em1(IMPC)BayhomozygoteE9.5N/A * 
embryonic growth retardation1 supporting datasetNdufb5em1(IMPC)BayheterozygoteE9.5N/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetNdufb5em1(IMPC)BayhomozygoteE12.5N/A * 
abnormal neural tube closure1 supporting datasetNdufb5em1(IMPC)BayhomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ndufb5em1(IMPC)BayExon Deletionmouse
Ndufb5tm402102(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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