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Gene: Cpb2 MGI:1891837

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
carboxypeptidase B2
Synonyms:
CPR,  thrombin-activatable fibrinolysis inhibitor,  carboxypeptidase R,  TAFI,  CPU,  carboxypeptidase U,  1110032P04Rik,  4930405E17Rik

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IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Cpb2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Cpb2 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Von Willebrand Disease, X-Linked Form
Prolonged bleeding time OMIM:314560
Athrombia, Essential
Impaired platelet adhesion, Prolonged bleeding time, Impaired platelet aggregation OMIM:209050
Von Willebrand Disease, Platelet-Type
Prolonged bleeding time OMIM:177820
Interstitial Lung Disease 2
Usual interstitial pneumonia, Alveolar cell carcinoma, Increased circulating antibody level, Pulm... OMIM:178500
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 3
Usual interstitial pneumonia, Pulmonary fibrosis OMIM:616373
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 4
Pulmonary fibrosis, Honeycomb lung OMIM:616371
Tatsumi Factor Deficiency
Prolonged bleeding time OMIM:272650
Idiopathic Pulmonary Fibrosis
Reticular pattern on pulmonary HRCT, Usual interstitial pneumonia, Honeycomb lung, Abnormal pulmo... ORPHA:2032
Riddle Syndrome
Decreased circulating IgG level, Pulmonary fibrosis OMIM:611943
Hypersensitivity Pneumonitis, Familial
Hypersensitivity pneumonitis OMIM:145300
Cystic Hamartoma Of Lung And Kidney
Recurrent respiratory infections, Pulmonary fibrosis ORPHA:2111
Pulmonary Hemosiderosis
Pulmonary fibrosis, Recurrent intrapulmonary hemorrhage OMIM:178550
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 9
Pulmonary fibrosis OMIM:620400
Surfactant Metabolism Dysfunction, Pulmonary, 3
Crazy paving pattern, Reticular pattern on pulmonary HRCT, Usual interstitial pneumonia, Intraalv... OMIM:610921
Glanzmann Thrombasthenia 2
Decreased platelet glycoprotein IIb-IIIa, Impaired clot retraction, Impaired ADP-induced platelet... OMIM:619267
Poikiloderma, Hereditary Fibrosing, With Tendon Contractures, Myopathy, And Pulmonary Fibrosis
Pulmonary fibrosis, Elevated circulating creatine kinase concentration OMIM:615704
Chronic Beryllium Disease
Pulmonary fibrosis, Hypersensitivity pneumonitis, Reticulonodular pattern on pulmonary HRCT, Lymp... ORPHA:133
Surfactant Metabolism Dysfunction, Pulmonary, 2
Recurrent pneumonia, Intralobular septal thickening, Spontaneous pneumothorax, Intraalveolar phos... OMIM:610913
Acute Interstitial Pneumonia
Reticulonodular pattern on pulmonary HRCT, Atelectasis, Interlobular septal thickening, Nodular p... ORPHA:79126
Immunodeficiency, Ovarian Dysgenesis, And Pulmonary Fibrosis
Decreased circulating total IgM, Decreased circulating IgG level, Decreased circulating IgA level... OMIM:611926
Plectin-Related Limb-Girdle Muscular Dystrophy R17
Elevated circulating creatine kinase concentration, Bronchiolitis, Atelectasis, Pulmonary fibrosis ORPHA:254361
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 5
Pulmonary fibrosis OMIM:618674
Autoimmune Interstitial Lung, Joint, And Kidney Disease
Elevated circulating C-reactive protein concentration, Hemosiderin-laden macrophages in bronchoal... OMIM:616414
Interstitial Lung Disease 1
Usual interstitial pneumonia, Intralobular septal thickening, Interlobular septal thickening, Ele... OMIM:619611
Immunodeficiency 60 And Autoimmunity
Decreased circulating IgG level, Decreased circulating IgA level, Recurrent sinopulmonary infecti... OMIM:618394
Autosomal Recessive Spastic Paraplegia Type 70
Abnormal pulmonary interstitial morphology ORPHA:401835
Sarcoidosis, Susceptibility To, 2
Emphysema, Pleural effusion, Pneumothorax, Abnormal pulmonary interstitial morphology, Pulmonary ... OMIM:612387
Bleeding Disorder, Platelet-Type, 18
Impaired ADP-induced platelet aggregation, Prolonged bleeding time, Impaired epinephrine-induced ... OMIM:615888
Pulmonary Fibrosis-Hepatic Hyperplasia-Bone Marrow Hypoplasia Syndrome
Abnormal pleura morphology, Pulmonary fibrosis, Increased circulating ferritin concentration ORPHA:210136
Retinal Dystrophy With Or Without Extraocular Anomalies
Pulmonary fibrosis OMIM:617175
Asbestos Intoxication
Abnormal pulmonary interstitial morphology, Atelectasis, Interlobular septal thickening, Lung ade... ORPHA:2302
Pulmonary Nodular Lymphoid Hyperplasia
Nodular pattern on pulmonary HRCT ORPHA:60026
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 1
Reticular pattern on pulmonary HRCT, Usual interstitial pneumonia, Pulmonary fibrosis OMIM:614742
Immunodeficiency 85 And Autoimmunity
Decreased circulating IgG level, Decreased circulating IgA level, Decreased circulating total IgM... OMIM:619510
Acute Lung Injury
Pneumonia, Diffuse alveolar hemorrhage, Increased circulating interleukin 6 concentration, Abnorm... ORPHA:178320
Hemophagocytic Lymphohistiocytosis, Familial, 5, With Or Without Microvillus Inclusion Disease
Recurrent upper respiratory tract infections, Increased circulating ferritin concentration, Recur... OMIM:613101
Platelet Glycoprotein Iv Deficiency
Prolonged bleeding time OMIM:608404
Immunodeficiency 73B With Defective Neutrophil Chemotaxis And Lymphopenia
Decreased circulating IgG level, Recurrent pneumonia, Recurrent sinusitis, Chronic bronchitis, Re... OMIM:618986
Aspergillosis
Pneumonia, Increased circulating IgE level, Pleural effusion, Hypersensitivity pneumonitis, Pulmo... ORPHA:1163
Bleeding Disorder, Platelet-Type, 11
Impaired ristocetin-induced platelet aggregation, Impaired collagen-induced platelet aggregation,... OMIM:614201
Antisynthetase Syndrome
Abnormal pulmonary interstitial morphology, Recurrent respiratory infections, Pulmonary fibrosis,... ORPHA:81
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 2
Pulmonary fibrosis OMIM:614743
Limited Cutaneous Systemic Sclerosis
Pulmonary fibrosis ORPHA:220402
Idiopathic Pulmonary Hemosiderosis
Reticular pattern on pulmonary HRCT, Diffuse alveolar hemorrhage, Nodular pattern on pulmonary HR... ORPHA:99931
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 6
Pulmonary fibrosis, Decreased circulating antibody level OMIM:619767
Fanconi Renotubular Syndrome 5
Emphysema, Pulmonary fibrosis, Lung adenocarcinoma OMIM:618913
Glanzmann Thrombasthenia 1
Decreased platelet glycoprotein IIb-IIIa, Impaired clot retraction, Impaired ADP-induced platelet... OMIM:273800
Bronchiolitis Obliterans
Pneumonia, Bronchiolitis obliterans, Bronchiectasis, Respiratory tract infection ORPHA:1303
Choreoathetosis And Congenital Hypothyroidism With Or Without Pulmonary Dysfunction
Atelectasis, Cystic pattern on pulmonary HRCT, Recurrent respiratory infections, Pulmonary fibros... OMIM:610978
Respiratory Bronchiolitis-Interstitial Lung Disease Syndrome
Emphysema, Respiratory tract infection, Chronic bronchitis, Honeycomb lung, Hypersensitivity pneu... ORPHA:79127
Scedosporiosis
Pneumonia, Bronchitis, Pulmonary fibrosis, Pleuritis, Pleural empyema ORPHA:449280
Polymyositis
Abnormal pulmonary interstitial morphology, Pulmonary fibrosis, Elevated circulating creatine kin... ORPHA:732
Bone Marrow Failure Syndrome 5
Pulmonary fibrosis, Decreased circulating antibody level OMIM:618165
Niemann-Pick Disease, Type B
Abnormal pulmonary interstitial morphology, Recurrent respiratory infections OMIM:607616
Congenital Myopathy 21 With Early Respiratory Failure
Lipoid pneumonia, Elevated circulating creatine kinase concentration OMIM:620326
Hereditary Mucoepithelial Dysplasia
Recurrent respiratory infections, Pulmonary fibrosis ORPHA:1839
X-Linked Intellectual Disability-Short Stature-Overweight Syndrome
Pulmonary fibrosis ORPHA:457240
Platelet Disorder, Undefined
Prolonged bleeding time, Impaired platelet aggregation OMIM:173420
Sting-Associated Vasculopathy, Infantile-Onset
Increased circulating IgA level, Elevated circulating C-reactive protein concentration, Increased... OMIM:615934
Hepatic Veno-Occlusive Disease-Immunodeficiency Syndrome
Abnormal circulating interleukin concentration, Recurrent respiratory infections, Panhypogammaglo... ORPHA:79124
Neonatal Acute Respiratory Distress Due To Sp-B Deficiency
Interstitial pneumonitis, Abnormal pulmonary interstitial morphology, Intraalveolar phospholipid ... ORPHA:217563
Riddle Syndrome
Pneumonia, Decreased circulating IgG level, Recurrent pneumonia, Bronchitis, Decreased circulatin... ORPHA:420741
Braddock Syndrome
Pulmonary fibrosis ORPHA:52047
Mixed Connective Tissue Disease
Abnormal pulmonary interstitial morphology, Pulmonary fibrosis, Pleuritis, Prolonged bleeding time ORPHA:809
Felty Syndrome
Recurrent pneumonia, Recurrent pharyngitis, Recurrent respiratory infections, Pulmonary fibrosis,... ORPHA:47612
Diffuse Alveolar Hemorrhage
Pulmonary fibrosis, Irregular septal thickening on pulmonary HRCT ORPHA:90060
Immunodeficiency 91 And Hyperinflammation
Recurrent pneumonia, Abnormal pulmonary interstitial morphology, Pulmonary hemorrhage, Pleural ef... OMIM:619644
Lung Disease, Immunodeficiency, And Chromosome Breakage Syndrome
Increased circulating IgE level, Bronchiolitis obliterans, Increased circulating IgM level OMIM:617241
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 8
Usual interstitial pneumonia, Pulmonary fibrosis OMIM:620367
Interstitial Pneumonitis, Desquamative, Familial
Recurrent upper respiratory tract infections, Desquamative interstitial pneumonitis, Type II pneu... OMIM:263000
Lymphoid Interstitial Pneumonia
Subpleural interstitial thickening, Respiratory tract infection, Multiple pulmonary cysts, Pulmon... ORPHA:79128
Rajab Interstitial Lung Disease With Brain Calcifications 2
Hypoalbuminemia, Abnormal pulmonary interstitial morphology OMIM:619013
Immunodeficiency 13
Recurrent upper respiratory tract infections, Recurrent pneumonia, Recurrent sinusitis, Bronchiol... OMIM:615518
Hermansky-Pudlak Syndrome 4
Pulmonary fibrosis OMIM:614073
Pulmonary Alveolar Microlithiasis
Bronchitis, Interlobular septal thickening, Subpleural interstitial thickening, Respiratory tract... ORPHA:60025
Hermansky-Pudlak Syndrome 1
Pulmonary fibrosis, Prolonged bleeding time OMIM:203300
Chronic Recurrent Multifocal Osteomyelitis 2, With Periostitis And Pustulosis
Elevated circulating C-reactive protein concentration, Pulmonary fibrosis OMIM:612852
Hermansky-Pudlak Syndrome 6
Recurrent upper respiratory tract infections, Impaired arachidonic acid-induced platelet aggregat... OMIM:614075
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 7
Emphysema, Pulmonary fibrosis OMIM:620365
Idiopathic Chronic Eosinophilic Pneumonia
Atelectasis, Increased circulating IgE level, Pleural effusion, Elevated circulating C-reactive p... ORPHA:2902
46,Xx Gonadal Dysgenesis
Pulmonary fibrosis ORPHA:243
Pulmonary Venoocclusive Disease 1, Autosomal Dominant
Pulmonary venous occlusion, Interlobular septal thickening OMIM:265450
Immune-Mediated Necrotizing Myopathy
Abnormal pulmonary interstitial morphology, Elevated circulating creatine kinase concentration ORPHA:206569
Hereditary Pulmonary Alveolar Proteinosis
Crazy paving pattern, Abnormal circulating protein concentration, Elevated circulating carcinoemb... ORPHA:264675
Hermansky-Pudlak Syndrome 2
Recurrent pneumonia, Pulmonary fibrosis, Impaired ADP-induced platelet aggregation, Prolonged ble... OMIM:608233
Interstitial Lung And Liver Disease
Abnormal pulmonary interstitial morphology, Pulmonary fibrosis, Intraalveolar phospholipid accumu... OMIM:615486
Granulomatous Disease, Chronic, Autosomal Recessive, 5
Recurrent pneumonia, Pulmonary fibrosis, Pleural effusion OMIM:618935
Factor V Deficiency
Prolonged bleeding time, Prolonged prothrombin time OMIM:227400
Surfactant Metabolism Dysfunction, Pulmonary, 1
Absent bronchoalveolar dimeric surfactant-protein B, Intraalveolar phospholipid accumulation, Int... OMIM:265120
Chitayat Syndrome
Abnormal pulmonary interstitial morphology, Recurrent respiratory infections OMIM:617180
Juvenile Dermatomyositis
Elevated circulating C-reactive protein concentration, Pulmonary fibrosis, Elevated circulating c... ORPHA:93672
Autoimmune Disease, Multisystem, Infantile-Onset, 1
Recurrent upper respiratory tract infections, Interstitial pneumonitis, Desquamative interstitial... OMIM:615952
Systemic Sclerosis
Abnormal pulmonary interstitial morphology, Pulmonary fibrosis, Elevated circulating creatine kin... ORPHA:90291
Diffuse Cutaneous Systemic Sclerosis
Pulmonary fibrosis ORPHA:220393
Brain-Lung-Thyroid Syndrome
Abnormal pulmonary interstitial morphology, Recurrent pneumonia, Pulmonary fibrosis, Recurrent re... ORPHA:209905
Autoimmune Lymphoproliferative Syndrome
Decreased circulating IgG level, Abnormal circulating interleukin concentration, Decreased specif... ORPHA:3261
Sarcoidosis, Susceptibility To, 1
Emphysema, Pleural effusion, Increased circulating antibody level, Abnormal pulmonary interstitia... OMIM:181000
Dyskeratosis Congenita, Autosomal Dominant 3
Abnormal pulmonary interstitial morphology, Pulmonary fibrosis OMIM:613990
Dyskeratosis Congenita, Autosomal Recessive 1
Pulmonary fibrosis OMIM:224230
Macrothrombocytopenia And Granulocyte Inclusions With Or Without Nephritis Or Sensorineural Hearing Loss
Impaired ADP-induced platelet aggregation, Prolonged bleeding time, Impaired epinephrine-induced ... OMIM:155100
Typhoid
Abnormal pulmonary interstitial morphology ORPHA:99745
Dyskeratosis Congenita, Autosomal Dominant 2
Pulmonary fibrosis OMIM:613989
Immunodeficiency 97 With Autoinflammation
Decreased circulating IgG level, Increased circulating ferritin concentration, Decreased circulat... OMIM:619802
Erdheim-Chester Disease
Abnormal pulmonary interstitial morphology, Pulmonary fibrosis, Pleural effusion ORPHA:35687
Dyskeratosis Congenita, Autosomal Dominant 1
Pulmonary fibrosis, Interstitial pneumonitis OMIM:127550
Fibrosis, Neurodegeneration, And Cerebral Angiomatosis
Decreased circulating IgG level, Recurrent respiratory infections, Pulmonary fibrosis, Atelectasis OMIM:618278
Thrombocytopenia, Paris-Trousseau Type
Prolonged bleeding time OMIM:188025
Overlap Myositis
Abnormal pulmonary interstitial morphology, Elevated circulating creatine kinase concentration ORPHA:206572
Wild Type Attr Amyloidosis
Pulmonary edema, Abnormal pulmonary interstitial morphology, Pleural effusion ORPHA:330001
Granulomatosis With Polyangiitis
Recurrent intrapulmonary hemorrhage, Elevated circulating C-reactive protein concentration, Recur... ORPHA:900
Niemann-Pick Disease, Type C2
Pulmonary fibrosis OMIM:607625
Primary Ciliary Dyskinesia
Atelectasis, Pulmonary situs ambiguus, Respiratory tract infection, Peribronchovascular interstit... ORPHA:244
Surfactant Metabolism Dysfunction, Pulmonary, 5
Intraalveolar phospholipid accumulation, Interlobular septal thickening OMIM:614370
Al Amyloidosis
Hypoalbuminemia, Increased circulating antibody level, Increased circulating NT-proBNP concentrat... ORPHA:85443
Storage Pool Platelet Disease
Prolonged bleeding time OMIM:185050
Cerebroretinal Microangiopathy With Calcifications And Cysts 1
Pulmonary fibrosis OMIM:612199
Bernard-Soulier Syndrome
Impaired ristocetin-induced platelet aggregation, Prolonged bleeding time OMIM:231200
Respiratory Infections, Recurrent, And Failure To Thrive With Or Without Diarrhea
Abnormal pulmonary interstitial morphology, Atelectasis, Pleural effusion, Recurrent lower respir... OMIM:620233
Agammaglobulinemia, X-Linked
Decreased circulating IgG level, Recurrent pneumonia, Decreased circulating IgA level, Recurrent ... OMIM:300755
Immunodeficiency 41 With Lymphoproliferation And Autoimmunity
Decreased specific anti-polysaccharide antibody level, Increased circulating IgE level, Decreased... OMIM:606367
Gaucher Disease
Increased circulating ferritin concentration, Increased circulating antibody level, Polyclonal el... ORPHA:355
Dermatomyositis
Lung adenocarcinoma, Elevated circulating creatine kinase concentration, Abnormal pulmonary inter... ORPHA:221
Hermansky-Pudlak Syndrome
Pulmonary fibrosis ORPHA:79430
Reactive Arthritis
Abnormal pleura morphology, Pulmonary fibrosis ORPHA:29207
Slc35A1-Cdg
Pneumonia, Pulmonary hemorrhage, Prolonged bleeding time ORPHA:238459
Gray Platelet Syndrome
Impaired thrombin-induced platelet aggregation, Impaired collagen-induced platelet aggregation, P... OMIM:139090
Gaucher Disease Type 1
Elevated circulating CCL18 level, Abnormal pulmonary interstitial morphology, Increased circulati... ORPHA:77259
Idiopathic Hypereosinophilic Syndrome
Pulmonary fibrosis, Pleural effusion ORPHA:3260
Prothrombin Deficiency, Congenital
Prolonged bleeding time, Prolonged prothrombin time OMIM:613679
Hermansky-Pudlak Syndrome 10
Abnormal pulmonary interstitial morphology, Recurrent respiratory infections OMIM:617050
Bronchial Neuroendocrine Tumor
Pneumonia, Abnormal pulmonary interstitial morphology ORPHA:97287
Von Willebrand Disease, Type 3
Prolonged bleeding time, Impaired platelet aggregation OMIM:277480
Gaucher Disease, Type I
Abnormal pulmonary interstitial morphology OMIM:230800
Autoimmune Pulmonary Alveolar Proteinosis
Crazy paving pattern, Abnormal circulating protein concentration, Intraalveolar phospholipid accu... ORPHA:747
Sarcoidosis
Chylothorax, Emphysema, Abnormal pleura morphology, Pleural effusion, Pneumothorax, Abnormal lung... ORPHA:797
Q Fever
Pneumonia, Abnormal pulmonary interstitial morphology, Pleural effusion, Increased circulating an... ORPHA:781
Gaucher Disease-Ophthalmoplegia-Cardiovascular Calcification Syndrome
Abnormal pulmonary interstitial morphology, Pulmonary fibrosis ORPHA:2072
Hermansky-Pudlak Syndrome 7
Prolonged bleeding time, Impaired platelet aggregation OMIM:614076
Dyskeratosis Congenita, X-Linked
Pulmonary fibrosis OMIM:305000
Pulmonary Capillary Hemangiomatosis
Diffuse alveolar hemorrhage, Interlobular septal thickening, Pleural effusion, Hemothorax, Pulmon... ORPHA:199241
Gaucher Disease Type 3
Abnormal pulmonary interstitial morphology, Recurrent respiratory infections, Increased circulati... ORPHA:77261
Bleeding Disorder, Platelet-Type, 17
Impaired collagen-induced platelet aggregation, Prolonged bleeding time, Impaired epinephrine-ind... OMIM:187900
Autoimmune Polyendocrinopathy Type 4
Abnormal pulmonary interstitial morphology, Decreased circulating antibody level ORPHA:227990
Primary Fanconi Renotubular Syndrome
Pulmonary fibrosis ORPHA:3337
Platelet Disorder, Familial, With Associated Myeloid Malignancy
Impaired arachidonic acid-induced platelet aggregation, Impaired ADP-induced platelet aggregation... OMIM:601399
Fusariosis
Pneumonia, Pleural effusion, Lung abscess, Hypersensitivity pneumonitis, Bronchiectasis ORPHA:228119
Primary Sjögren Syndrome
Usual interstitial pneumonia, Bronchitis, Increased circulating antibody level, Lymphocytic inter... ORPHA:289390
Autoimmune Polyendocrinopathy Type 3
Abnormal pulmonary interstitial morphology, Decreased circulating antibody level ORPHA:227982
Rajab Interstitial Lung Disease With Brain Calcifications 1
Emphysema, Abnormal pulmonary interstitial morphology, Hypoalbuminemia OMIM:613658
Kawasaki Disease
Elevated circulating C-reactive protein concentration, Abnormal pulmonary interstitial morphology... ORPHA:2331
Brucellosis
Pneumonia, Pulmonary granulomatosis, Bronchitis, Pleural effusion, Lung abscess, Elevated circula... ORPHA:1304
Knobloch Syndrome 2
Abnormal pulmonary interstitial morphology, Recurrent respiratory infections OMIM:618458
Epidermolysis Bullosa, Junctional 7, With Interstitial Lung Disease And Nephrotic Syndrome
Hypoalbuminemia, Abnormal pulmonary interstitial morphology, Recurrent respiratory infections OMIM:614748
Kikuchi-Fujimoto Disease
Elevated circulating C-reactive protein concentration, Abnormal pulmonary interstitial morphology... ORPHA:50918
Farber Disease
Recurrent upper respiratory tract infections, Nodular pattern on pulmonary HRCT, Atelectasis ORPHA:333
Chronic Visceral Acid Sphingomyelinase Deficiency
Abnormal pulmonary interstitial morphology, Interstitial pneumonitis ORPHA:77293
Cryptococcosis
Pneumonia, Nodular pattern on pulmonary HRCT, Pleural effusion ORPHA:1546
Chronic Graft Versus Host Disease
Bronchiolitis obliterans, Pneumothorax, Pleural effusion, Bronchiectasis ORPHA:99921
Ehlers-Danlos Syndrome, Vascular Type
Diffuse alveolar hemorrhage, Spontaneous pneumothorax, Emphysema, Nodular pattern on pulmonary HR... OMIM:130050
Goodpasture Syndrome
Reticular pattern on pulmonary HRCT, Pulmonary hemorrhage, Nodular pattern on pulmonary HRCT, Blo... OMIM:233450

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Cpb2

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Cpb2.

No publications found that use IMPC mice or data for Cpb2.

Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cpb2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Cpb2tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Cpb2em1(IMPC)Ccpcz Exon Deletion Mice
Cpb2tm2e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells
Cpb2tm1e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells

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