Genes Phenotypes

Gene: Dctn5

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Name
dynactin 5
MGI ID
MGI:1891689
Synonyms
4930427E12Rik p25 dynactin subunit b2b315Clo
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (142) All data table (255)
Expression & images (45) Disease models (0) Order (3)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal lens morphology Dctn5tm2a(KOMP)Wtsi HET Early adult 1.18×10-05
cataract Dctn5tm2a(KOMP)Wtsi HET Early adult 9.83×10-06
increased hematocrit Dctn5tm2a(KOMP)Wtsi HET Early adult 3.38×10-05
preweaning lethality, complete penetrance Dctn5tm2a(KOMP)Wtsi HOM Early adult 0.00
abnormal behavior Dctn5tm2a(KOMP)Wtsi HET Early adult 6.19×10-05
decreased hematocrit Dctn5tm2a(KOMP)Wtsi HET Early adult 3.38×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (1/2) N/A
Aorta 2 No N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/2) N/A
Lung 2 No  (1/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No  (1/2) N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (1/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle tissue 2 No  (1/2) N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Dctn5tm2a(KOMP)Wtsi
brain, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
testis, HET, Male, WTSI
Dctn5tm2a(KOMP)Wtsi
peripheral nervous system, pituitary gland, HET, Male, WTSI
Dctn5tm2a(KOMP)Wtsi
kidney, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
cartilage tissue, HET, Female, WTSI

View all 17 images

Dctn5tm2a(KOMP)Wtsi
testis, HET, Male, WTSI
Dctn5tm2a(KOMP)Wtsi
kidney, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
heart, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
thymus, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
trachea, HET, Female, WTSI

View all 12 images

Dctn5tm2a(KOMP)Wtsi
brain, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
peripheral nervous system, pituitary gland, HET, Male, WTSI
Dctn5tm2a(KOMP)Wtsi
brain, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
spinal cord, HET, Male, WTSI
Dctn5tm2a(KOMP)Wtsi
large intestine, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
small intestine, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
testis, HET, Male, WTSI
Dctn5tm2a(KOMP)Wtsi
ovary, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
trachea, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
lung, HET, Male, WTSI
Dctn5tm2a(KOMP)Wtsi
cartilage tissue, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
cartilage tissue, HET, Male, WTSI
Dctn5tm2a(KOMP)Wtsi
kidney, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
heart, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
adrenal gland, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
thymus, HET, Female, WTSI
No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images
Dctn5tm2a(KOMP)Wtsi
body, HET, Male, WTSI
Dctn5tm2a(KOMP)Wtsi
body, HET, Male, WTSI
Dctn5tm2a(KOMP)Wtsi
head, HET, Male, WTSI
Dctn5tm2a(KOMP)Wtsi
head, HET, Male, WTSI
Dctn5tm2a(KOMP)Wtsi
body, HET, Male, WTSI

View all 72 images

Dctn5tm2a(KOMP)Wtsi
back skin, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
back skin, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
back skin, HET, Female, WTSI
Dctn5tm2a(KOMP)Wtsi
back skin, HET, Female, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Dctn5tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Dctn5tm41679(L1L2_Pgk_PM) Targeting vectors
Dctn5tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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