Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Prkag3 by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Maturity-Onset Diabetes Of The Young, Type 7 | Type II diabetes mellitus, Maturity-onset diabetes of the young | OMIM:610508 | |
Maturity-Onset Diabetes Of The Young, Type 4 | Type II diabetes mellitus, Maturity-onset diabetes of the young | OMIM:606392 | |
Type 1 Diabetes Mellitus 15 | Type I diabetes mellitus, Diabetes mellitus | OMIM:601666 | |
Type 1 Diabetes Mellitus 6 | Diabetes mellitus | OMIM:601941 | |
Type 1 Diabetes Mellitus 10 | Diabetes mellitus | OMIM:601942 | |
Type 2 Diabetes Mellitus | Insulin resistance, Type II diabetes mellitus | OMIM:125853 | |
Maturity-Onset Diabetes Of The Young, Type 3 | Hyperglycemia, Type II diabetes mellitus, Maturity-onset diabetes of the young | OMIM:600496 | |
Acanthosis Nigricans With Muscle Cramps And Acral Enlargement | Insulin resistance | OMIM:200170 |
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MGI Allele | Allele Type | Produced |
---|---|---|
Prkag3tm1e(KOMP)Wtsi | Targeted, non-conditional allele | ES Cells |
Prkag3tm93279(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors |
Prkag3tm93279(L1L2_Pgk_P) | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors |
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