Gene: Gmds

Name
GDP-mannose 4, 6-dehydratase
MGI ID
MGI:1891112
Synonyms
N/A
View
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased alpha-beta T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 2.26×10-05
increased Ly6C high monocyte number Gmdstm1a(KOMP)Wtsi HOM postnatal 2.26×10-05
decreased Ly6C-positive mature NK cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
increased CD4-negative NK T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased memory-marker CD4-positive NK T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
increased Ly6C-positive NK T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
increased memory-marker NK cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
increased gamma-delta T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
abnormal cranium morphology Gmdstm1a(KOMP)Wtsi HOM postnatal 4.52×10-07
decreased plasmacytoid dendritic cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased KLRG1-positive NK cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased B cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 2.12×10-05
decreased CD8-positive, naive alpha-beta T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
increased granulocyte number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
increased monocyte cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
increased immature NK cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased CD4-positive NK T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased memory-marker CD4-negative NK T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
increased neutrophil cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased CD8-positive, alpha-beta T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased circulating magnesium level Gmdstm1a(KOMP)Wtsi HOM postnatal 2.83×10-05
increased mature B cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 9.00×10-07
increased CD8-positive, alpha-beta T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
increased B cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 9.00×10-07
increased NK T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased dendritic cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased KLRG1+ CD8 alpha beta T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased effector memory CD8-positive, alpha-beta T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased T-helper cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased mature NK cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased CD4-positive, alpha beta T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased transitional stage T2 B cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
increased CD4-positive, alpha beta T cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased macrophage cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00
decreased NK cell number Gmdstm1a(KOMP)Wtsi HOM postnatal 0.00

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Lateral Orientation
28 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Dorso Ventral
42 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
Spleen Immunophenotyping: Images associated with FACS analysis
193 Images
Mesenteric Lymph Node Immunophenotyping: Images associated with FACS analysis
36 Images
Anti-nuclear antibody assay
6 Images
DSS Histology
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Gmdstm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Gmdstm302436(L1L2_Bact_P) Targeting vectors

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