Gene: Nek7

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Name
NIMA (never in mitosis gene a)-related expressed kinase 7
MGI ID
MGI:1890645
Synonyms
2810460C19Rik
Viability
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased urine glucose level Nek7tm1b(EUCOMM)Hmgu HET Early adult 2.45×10-05
increased urine microalbumin level Nek7tm1b(EUCOMM)Hmgu HET Early adult 6.11×10-08
preweaning lethality, complete penetrance Nek7tm1b(EUCOMM)Hmgu HOM   Early adult 0.00
decreased circulating glucose level Nek7tm1b(EUCOMM)Hmgu HET Early adult 9.80×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (1/2)  Section images
Aorta 2 No  (1/583)  (2/2)  Section images
Brain 2 No  (4/583)  (2/2)  Section images
Brainstem 2 No  (2/583)  (2/2)  Section images
Brown adipose tissue 2 No  (2/2)  Section images
Cartilage tissue 2 No  (1/583)  (2/2)  Section images
Cerebellum 2 No  (3/583)  (2/2)  Section images
Cerebral cortex 2 No  (2/583)  (2/2)  Section images
Epididymis 2 No  (18/132)  (1/2)  Section images
Esophagus 2 No  (7/407)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/583)  (2/2)  Section images
Hippocampus 2 No  (3/583)  (2/2)  Section images
Hypothalamus 2 No  (2/583)  (2/2)  Section images
Kidney 2 No  (21/583)  (2/2)  Section images
Large intestine 2 No  (10/583)  (2/2)  Section images
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583)  (2/2)  Section images
Lymph node 2 No  (1/583)  (2/2)  Section images
Mammary gland 2 No  (1/2)  Section images
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/583)  (2/2)  Section images
Ovary 2 No  (1/583)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/583)  (2/2)  Section images
Peripheral nervous system 2 No  (2/583)  (2/2)  Section images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583)  (1/2)  Section images
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583)  (2/2)  Section images
Small intestine 2 No  (9/583)  (2/2)  Section images
Spinal cord 2 No  (3/583)  (2/2)  Section images
Spleen 2 No  (3/583)  (2/2)  Section images
Stomach 2 No  (13/583)  (2/2)  Section images
Striatum 2 No  (3/583)  (2/2)  Section images
Submandibular gland 2 No  (2/130)  (2/2)  Section images
Testis 2 No  (6/583)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  (1/583)  (2/2)  Section images
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583)  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2)  Section images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505)  (2/3) N/A
2  (1/60) N/A
2  (1/505) N/A
2  (1/506)  (2/3)  Wholemount images
2  (1/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/61) Image Only N/A
2  (1/505)  (2/3) N/A
2  (5/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (6/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/503) N/A
2  (1/503) Image Only N/A
2  (1/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/75)  (2/3) N/A
2  (1/503) Image Only N/A
2  (1/505)  (2/3) N/A
2  (1/72)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/505) N/A

 Associated Images

Sleep Wake: Wake state (bmp file)
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
12 Images
Original Image
Adult LacZ: LacZ Images Section
44 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Gross Morphology Embryo E12.5
2 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Nek7tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Nek7tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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