Gene: Pes1

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal snout morphology Pes1tm1b(EUCOMM)Wtsi HET postnatal 7.23×10-05
preweaning lethality, complete penetrance Pes1tm1b(EUCOMM)Wtsi HOM n/a 0.00
decreased circulating fructosamine level Pes1tm1b(EUCOMM)Wtsi HET postnatal 8.54×10-05
embryonic lethality prior to organogenesis Pes1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
decreased circulating creatine kinase level Pes1tm1b(EUCOMM)Wtsi HET postnatal 5.88×10-07
increased circulating creatine kinase level Pes1tm1b(EUCOMM)Wtsi HET postnatal 5.88×10-07
embryonic lethality prior to tooth bud stage Pes1tm1b(EUCOMM)Wtsi HOM embryonic day 12.5 0.00
decreased circulating total protein level Pes1tm1b(EUCOMM)Wtsi HET postnatal 9.11×10-07

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No  (1/2)  Wholemount images
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No  (2/2)  Wholemount images
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No  (2/2)  Wholemount images
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (1/2)  Wholemount images
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485)  (1/1) N/A
Ear 1  (1/485) N/A
Embryo 1  (1/485)  (1/1) N/A
Eye 1  (1/485)  (1/1) N/A
Foot 1  (1/485)  (1/1) N/A
Forebrain 1  (1/485)  (1/1) N/A
Forelimb 1  (1/485)  (1/1) N/A
Hand 1  (1/485)  (1/1) N/A
Head 1  (5/485)  (1/1) N/A
Heart 1  (1/485) Image Only N/A
Hindbrain 1  (6/485)  (1/1) N/A
Hindlimb 1  (1/485)  (1/1) N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) N/A
Mandibular process 1  (1/485) N/A
Maxillary process 1  (1/485) N/A
Midbrain 1  (1/485)  (1/1) N/A
Oral cavity 1  (1/485) N/A
Skin 1  (1/485) N/A
Tail 1  (1/485)  (1/1) N/A
Tail somite 1  (1/485) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
4 Images
Echo: M-Mode Images
20 Images
Adult LacZ: LacZ Images Wholemount
21 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Pes1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Pes1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Pes1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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