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Genes Phenotypes Help, News, Blog

Gene: Pes1

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Name
pescadillo ribosomal biogenesis factor 1
MGI ID
MGI:1890613
Synonyms
N/A
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (8) Measurements chart (214) All data table (406)
Expression & images (46) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to tooth bud stage Pes1tm1b(EUCOMM)Wtsi HOM   E12.5 0.00
decreased circulating total protein level Pes1tm1b(EUCOMM)Wtsi HET Early adult 2.35×10-10
preweaning lethality, complete penetrance Pes1tm1b(EUCOMM)Wtsi HOM   Early adult 0.00
decreased circulating serum albumin level Pes1tm1b(EUCOMM)Wtsi HET Early adult 2.93×10-07
abnormal snout morphology Pes1tm1b(EUCOMM)Wtsi HET   Early adult 5.65×10-05
embryonic lethality prior to organogenesis Pes1tm1b(EUCOMM)Wtsi HOM   E9.5 0.00
decreased circulating fructosamine level Pes1tm1b(EUCOMM)Wtsi HET Early adult 2.54×10-08
decreased circulating calcium level Pes1tm1b(EUCOMM)Wtsi HET Early adult 3.61×10-05

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2)  Wholemount images
Aorta 2 No  (1/583) N/A
Bone 2 No N/A
Brain 2 No  (4/583)  (2/2)  Wholemount images
Brainstem 2 No  (2/583)  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583)  (2/2)  Wholemount images
Cerebellum 2 No  (3/583)  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/583)  (2/2)  Wholemount images
Esophagus 2 No  (7/407)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/583)  (2/2)  Wholemount images
Hippocampus 2 No  (3/583)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/583)  (2/2)  Wholemount images
Kidney 2 No  (21/583)  (2/2)  Wholemount images
Large intestine 2 No  (10/583)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (1/583)  (2/2)  Wholemount images
Lung 2 No  (2/583)  (2/2)  Wholemount images
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/583)  (2/2)  Wholemount images
Oral epithelium 2 No  (1/2)  Wholemount images
Ovary 2 No  (1/583)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563)  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/583)  (2/2)  Wholemount images
Peyer's patch 2 No  (2/2)  Wholemount images
Pituitary gland 2 No  (1/583)  (2/2)  Wholemount images
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No  (2/2)  Wholemount images
Skin 2 No  (1/583)  (2/2)  Wholemount images
Small intestine 2 No  (9/583)  (2/2)  Wholemount images
Spinal cord 2 No  (3/583)  (2/2)  Wholemount images
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583)  (2/2)  Wholemount images
Striatum 2 No  (3/583)  (2/2)  Wholemount images
Testis 2 No  (6/583)  (1/2)  Wholemount images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583)  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (1/2)  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (2)
Heart expression
MA:0000072
digestive system (5)
Large Intestine expression
MA:0000333
endocrine system (2)
Adrenal gland expression
MA:0000116
immune system (2)
Small Intestine expression
Peyers Patch expression
MA:0000137
MA:0000337
integumental system (1)
Skin expression
MA:0000151
musculoskeletal system (1)
Skeletal Muscle expression
Cartilage tissue expression
MA:0003148
MA:0000104
nervous system (5)
Brain expression
Brainstem expression
Cerebral Cortex expression
Cerebellum expression
Hippocampus expression
Hypothalamus expression
Olfactory Lobe expression
Striatum expression
MA:0000191
MA:0000169
MA:0000198
MA:0000891
MA:0000168
MA:0002413
MA:0000185
MA:0000173
postnatal mouse (21)
Adrenal gland expression
MA:0000116
reproductive system (2)
Ovary expression
Oviduct expression
Uterus expression
MA:0000384
MA:0000389
MA:0000385
respiratory system (3)
Lung expression
MA:0000415
set of connective tissues (2)
Skeletal Muscle expression
Cartilage tissue expression
MA:0003148
MA:0000104
trunk (12)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

thumbnail
Echo: M-Mode Images
20 Images
thumbnail
Adult LacZ: LacZ Images Wholemount
21 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Pes1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Pes1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Pes1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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