Genes Phenotypes

Gene: Srsf4

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Name
serine/arginine-rich splicing factor 4
MGI ID
MGI:1890577
Synonyms
5730499P16Rik MNCb-2616 Sfrs4 SRp75
Viability
Homozygous - Subviable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (473) All data table (2069)
Expression & images (45) Disease models (0) Order (1)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating creatinine level Srsf4tm1a(EUCOMM)Wtsi HET postnatal 1.87×10-05
preweaning lethality, incomplete penetrance Srsf4tm1a(EUCOMM)Wtsi HOM n/a 0.00
abnormal tail movements Srsf4tm1a(EUCOMM)Wtsi HET postnatal 8.64×10-06
abnormal behavior Srsf4tm1a(EUCOMM)Wtsi HET postnatal 8.28×10-13

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  (4/4) N/A
Aorta 4 No N/A
Blood vessel 4 No  (4/4) N/A
Bone 4 No N/A
Brain 4 No  (4/4) N/A
Brainstem 4 No N/A
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No  (4/4) N/A
Cerebellum 4 No N/A
Cerebral cortex 4 No N/A
Eye 4 No  (1/4) N/A
Gall bladder 4 No  (2/4) N/A
Heart 4 No  (2/4) N/A
Hippocampus 4 No N/A
Hypothalamus 4 No N/A
Kidney 4 No  (18/584)  (4/4) N/A
Large intestine 4 No  (10/584)  (3/4) N/A
Liver 4 No  (3/4) N/A
Lower urinary tract 4 No  (4/4) N/A
Lung 4 No  (4/4) N/A
Lymph node 4 No  (2/4) N/A
Mammary gland 4 No N/A
Esophagus 4 No  (4/4) N/A
Olfactory lobe 4 No N/A
Ovary 4 No  (1/584)  (2/4) N/A
Oviduct 4 No  (2/4) N/A
Pancreas 4 No  (5/584)  (2/4) N/A
Parathyroid gland 4 No  (4/4) N/A
Peripheral nervous system 4 No  (3/4) N/A
Peyer's patch 4 No  (4/4) N/A
Pituitary gland 4 No  (1/4) N/A
Prostate gland 4 No  (12/584)  (2/4) N/A
Skeletal muscle tissue 4 No  (4/4) N/A
Skin 4 No  (4/4) N/A
Small intestine 4 No  (9/584)  (3/4) N/A
Spinal cord 4 No  (4/4) N/A
Spleen 4 No  (2/584)  (4/4) N/A
Stomach 4 No  (12/584)  (2/4) N/A
Striatum 4 No N/A
Testis 4 No  (2/584)  (2/4) N/A
Thymus 4 No  (4/4) N/A
Thyroid gland 4 No  (15/584)  (4/4) N/A
Trachea 4 No  (4/4) N/A
Uterus 4 No  (2/4) N/A
White adipose tissue 4 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Srsf4tm1a(EUCOMM)Wtsi
lung, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
large intestine, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
kidney, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
inguinal fat pad, skin, mammary gland, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
thyroid gland, HET, Female, WTSI

View all 19 images

Srsf4tm1a(EUCOMM)Wtsi
lung, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
large intestine, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
kidney, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Srsf4tm1a(EUCOMM)Wtsi
heart, HET, Female, WTSI

View all 11 images

Srsf4tm1a(EUCOMM)Wtsi
large intestine, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
oesophagus, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
peyer's patch, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
peyer's patch, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
spleen, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
thymus, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
peripheral nervous system, pituitary gland, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
inguinal fat pad, skin, mammary gland, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
skin, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Srsf4tm1a(EUCOMM)Wtsi
uterus, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
inguinal fat pad, skin, mammary gland, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
cartilage tissue, HET, Male, WTSI
Srsf4tm1a(EUCOMM)Wtsi
kidney, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
inguinal fat pad, skin, mammary gland, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
heart, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
thyroid gland, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
inguinal fat pad, skin, mammary gland, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
lung, HET, Female, WTSI
Srsf4tm1a(EUCOMM)Wtsi
eye, HET, Male, WTSI
No Embryo expression data was found for this gene.

 Associated Images

Phenotype associated images not available

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Srsf4tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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