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Gene: Laptm4b MGI:1890494

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Gene Summary

Name:
lysosomal-associated protein transmembrane 4B
Synonyms:
C330023P13Rik

Order Alleles

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal eye morphology Laptm4btm1e.1(KOMP)Wtsi HOM E12.5 0.00
abnormal midbrain morphology Laptm4btm1e.1(KOMP)Wtsi HOM E12.5 0.00
abnormal neural tube closure Laptm4btm1e.1(KOMP)Wtsi HOM E12.5 0.00
abnormal craniofacial morphology Laptm4btm1e.1(KOMP)Wtsi HOM E15.5 0.00
preweaning lethality, incomplete penetrance Laptm4btm1e.1(KOMP)Wtsi HOM   Early adult 0.00
increased startle reflex Laptm4btm1e.1(KOMP)Wtsi HET Early adult 9.68×10-06
edema Laptm4btm1e.1(KOMP)Wtsi HOM E15.5 0.00
preweaning lethality, complete penetrance Laptm4btm1e.1(KOMP)Wtsi HOM Early adult 0.00
decreased prepulse inhibition Laptm4btm1e.1(KOMP)Wtsi HET Early adult 1.14×10-08
abnormal embryo size Laptm4btm1e.1(KOMP)Wtsi HOM E12.5 0.00
abnormal hindbrain morphology Laptm4btm1e.1(KOMP)Wtsi HOM E12.5 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

No Adult expression data was found for this gene.

An assay measuring the expression of lacZ shows the tissue where the gene is expressed.

Anatomy Images Zygosity Mutant Expr
N/A Ambiguous
Axial skeleton N/A homozygote 0.0% (0 of 2)
Brain N/A heterozygote Ambiguous
Brain N/A homozygote 0.0% (0 of 5)
N/A Ambiguous
Central nervous system ganglion N/A homozygote 0.0% (0 of 2)
Ear N/A heterozygote Ambiguous
Ear N/A homozygote 0.0% (0 of 5)
Embryo N/A heterozygote 0.0% (0 of 3)
Embryo N/A homozygote 0.0% (0 of 5)
Eye N/A heterozygote Ambiguous
Eye N/A homozygote 0.0% (0 of 5)
Footplate N/A heterozygote Ambiguous
Footplate N/A homozygote 0.0% (0 of 5)
Forebrain N/A heterozygote Ambiguous
Forebrain N/A homozygote 0.0% (0 of 5)
Forelimb N/A heterozygote Ambiguous
Forelimb N/A homozygote 0.0% (0 of 5)
N/A Ambiguous
Gut N/A homozygote 0.0% (0 of 2)
Handplate N/A heterozygote Ambiguous
Handplate N/A homozygote 0.0% (0 of 5)
Head N/A heterozygote Ambiguous
Head N/A homozygote 0.0% (0 of 5)
Heart N/A heterozygote Ambiguous
Heart N/A homozygote 0.0% (0 of 5)
Hindbrain N/A heterozygote Ambiguous
Hindbrain N/A homozygote 0.0% (0 of 5)
Hindlimb N/A heterozygote Ambiguous
Hindlimb N/A homozygote 0.0% (0 of 5)
Liver N/A heterozygote Ambiguous
Liver N/A homozygote 20% (1 of 5)
Lung N/A heterozygote Ambiguous
Lung N/A homozygote 0.0% (0 of 5)
Mandibular process N/A heterozygote Ambiguous
Mandibular process N/A homozygote 0.0% (0 of 5)
Maxillary process N/A heterozygote Ambiguous
Maxillary process N/A homozygote 0.0% (0 of 5)
Midbrain N/A heterozygote Ambiguous
Midbrain N/A homozygote 0.0% (0 of 5)
N/A Ambiguous
Nose N/A homozygote 0.0% (0 of 2)
Oral cavity N/A heterozygote Ambiguous
Oral cavity N/A homozygote 0.0% (0 of 5)
N/A Ambiguous
Chorioallantoic placenta N/A homozygote 100% (2 of 2)
N/A Ambiguous
Skeleton N/A homozygote 0.0% (0 of 2)
Skin N/A heterozygote Ambiguous
Skin N/A homozygote 0.0% (0 of 5)
N/A Ambiguous
Spinal cord N/A homozygote 0.0% (0 of 2)
Tail somite N/A heterozygote Ambiguous
Tail somite N/A homozygote 0.0% (0 of 5)
Tail N/A heterozygote Ambiguous
Tail N/A homozygote 0.0% (0 of 5)
N/A Ambiguous
Trachea N/A homozygote 0.0% (0 of 2)
N/A Ambiguous
Urinary system N/A homozygote 50% (1 of 2)

Background staining occurs in wild type mice and embryos at an incidental rate.

Anatomy Background staining in controls (WT)

Background staining occurs in wild type mice and embryos at an incidental rate.

Background staining occurs in wild type embryos at a measurable rate.

Anatomy Background staining in controls(WT)
axial skeleton 1.56% (1 of 64)
brain 1.18% (6 of 510)
central nervous system ganglion 1.37% (1 of 73)
ear 0.2% (1 of 510)
embryo 0.39% (2 of 511)
eye 0.2% (1 of 510)
footplate 0.2% (1 of 510)
forebrain 0.2% (1 of 510)
forelimb 0.2% (1 of 510)
gut 1.69% (1 of 59)
handplate 0.2% (1 of 510)
head 0.98% (5 of 510)
heart 0.2% (1 of 510)
hindbrain 1.18% (6 of 510)
hindlimb 0.2% (1 of 510)
liver 0.2% (1 of 505)
lung 0.2% (1 of 505)
mandibular process 0.2% (1 of 510)
maxillary process 0.2% (1 of 510)
midbrain 0.2% (1 of 510)
nose 1.28% (1 of 78)
oral cavity 0.2% (1 of 505)
placenta 16.67% (7 of 42)
skeleton 1.28% (1 of 78)
skin 0.2% (1 of 510)
spinal cord 1.39% (1 of 72)
tail 0.2% (1 of 510)
tail somite group 0.2% (1 of 510)
trachea 1.69% (1 of 59)
urinary system 1.69% (1 of 59)

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Skull Lateral Orientation

10 Images

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MicroCT E14.5-E15.5

Embryo reconstruction

8 Images

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Embryo LacZ

LacZ images wholemount

32 Images

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X-ray

XRay Images Whole Body Lateral Orientation

10 Images

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Gross Morphology Embryo E14.5-E15.5

Images

10 Images

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X-ray

XRay Images Whole Body Dorso Ventral

10 Images

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X-ray

XRay Images Skull Dorso Ventral Orientation

10 Images

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Gross Pathology and Tissue Collection

Images

8 Images

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Download thumbnail Download
Immunophenotyping

Panel A FCS file(s)

6 Images

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Immunophenotyping

Panel B FCS file(s)

6 Images

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X-ray

XRay Images Hind Leg and Hip

1 Images

View images

Human diseases caused by Laptm4b mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Laptm4b by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Joubert Syndrome 13
Cerebellar vermis hypoplasia, Molar tooth sign on MRI OMIM:614173
Meckel Syndrome 13
Occipital encephalocele, Molar tooth sign on MRI, Cerebellar hypoplasia OMIM:617562
Septopreoptic Holoprosencephaly
Rhombencephalosynapsis, Hypoplasia of the pons, Abnormal midbrain morphology, Ethmoidal encephalo... ORPHA:280195
Joubert Syndrome 25
Molar tooth sign on MRI, Cerebellar hypoplasia OMIM:616781
Joubert Syndrome 16
Encephalocele, Molar tooth sign on MRI, Dandy-Walker malformation OMIM:614465
Meckel Syndrome, Type 4
Intrauterine growth retardation, Hydrocephalus, Anencephaly, Agenesis of cerebellar vermis, Menin... OMIM:611134
Joubert Syndrome 36
Molar tooth sign on MRI OMIM:618763
Hydrolethalus Syndrome 2
Anencephaly, Hydrocephalus, Molar tooth sign on MRI OMIM:614120
Joubert Syndrome 4
Elongated superior cerebellar peduncle, Thickened superior cerebellar peduncle, Molar tooth sign ... OMIM:609583
Joubert Syndrome 10
Cerebellar vermis hypoplasia, Molar tooth sign on MRI OMIM:300804
Gómez-López-Hernández Syndrome
Cerebellar vermis hypoplasia, Hydrocephalus, Abnormal cerebellum morphology, Abnormal brainstem m... ORPHA:1532
Neural Tube Defects, Folate-Sensitive
Spinal dysraphism OMIM:601634
Meckel Syndrome, Type 10
Dilated fourth ventricle, Anencephaly, Cerebellar hypoplasia, Occipital encephalocele, Dandy-Walk... OMIM:614175
Joubert Syndrome 30
Dandy-Walker malformation, Superior cerebellar dysplasia, Molar tooth sign on MRI, Cerebellar atr... OMIM:617622
Spina Bifida-Hypospadias Syndrome
Spinal dysraphism, Spina bifida ORPHA:3176
Multiple Epiphyseal Dysplasia, Al-Gazali Type
Molar tooth sign on MRI ORPHA:166024
Hyperekplexia 3
Exaggerated startle response OMIM:614618
Joubert Syndrome 22
Intrauterine growth retardation, Molar tooth sign on MRI, Agenesis of cerebellar vermis OMIM:615665
Joubert Syndrome 18
Intrauterine growth retardation, Molar tooth sign on MRI OMIM:614815
Joubert Syndrome 7
Encephalocele, Molar tooth sign on MRI, Brainstem dysplasia, Hypoplasia of the brainstem OMIM:611560
Coach Syndrome 2
Cerebellar vermis hypoplasia, Hydrocephalus, Molar tooth sign on MRI OMIM:619111
Al-Gazali-Bakalinova Syndrome
Lymphedema, Molar tooth sign on MRI OMIM:607131
Joubert Syndrome 27
Molar tooth sign on MRI OMIM:617120
Developmental And Epileptic Encephalopathy 8
Exaggerated startle response OMIM:300607
Joubert Syndrome 33
Molar tooth sign on MRI OMIM:617767
Joubert Syndrome 32
Abnormal cerebellum morphology, Molar tooth sign on MRI OMIM:617757
Ravine Syndrome
Atrophy/Degeneration affecting the brainstem, Abnormal brainstem morphology ORPHA:99852
Joubert Syndrome 9
Encephalocele, Molar tooth sign on MRI OMIM:612285
Joubert Syndrome 6
Elongated superior cerebellar peduncle, Dilated fourth ventricle, Cerebellar vermis hypoplasia, T... OMIM:610688
Orofaciodigital Syndrome Xv
Molar tooth sign on MRI OMIM:617127
Ataxia-Intellectual Disability-Oculomotor Apraxia-Cerebellar Cysts Syndrome
Elongated superior cerebellar peduncle, Dilated fourth ventricle, Abnormal brainstem morphology, ... ORPHA:370022
Joubert Syndrome 17
Cerebellar vermis hypoplasia, Molar tooth sign on MRI OMIM:614615
Joubert Syndrome 40
Molar tooth sign on MRI OMIM:619582
Joubert Syndrome 31
Molar tooth sign on MRI OMIM:617761
Joubert Syndrome 35
Elongated superior cerebellar peduncle, Cerebellar vermis hypoplasia, Molar tooth sign on MRI OMIM:618161
Congenital Muscular Dystrophy With Cerebellar Involvement
Hydrocephalus, Abnormal cerebellum morphology, Occipital encephalocele, Hypoplasia of the pons, D... ORPHA:370959
Adult Krabbe Disease
Abnormal pons morphology, Abnormal medulla oblongata morphology, Abnormal midbrain morphology ORPHA:206448
Orofaciodigital Syndrome Vi
Cerebellar vermis hypoplasia, Molar tooth sign on MRI OMIM:277170
Short-Rib Thoracic Dysplasia 14 With Polydactyly
Hydrocephalus, Hydrops fetalis, Anencephaly, Polyhydramnios, Cerebellar vermis hypoplasia, Molar ... OMIM:616546
Joubert Syndrome 2
Elongated superior cerebellar peduncle, Hydrocephalus, Encephalocele, Dysgenesis of the cerebella... OMIM:608091
Joubert Syndrome 3
Elongated superior cerebellar peduncle, Cerebellar vermis hypoplasia, Molar tooth sign on MRI OMIM:608629
Slc35A2-Cdg
Atrophy/Degeneration affecting the brainstem, Cerebellar atrophy, Abnormal midbrain morphology, I... ORPHA:356961
Joubert Syndrome 20
Molar tooth sign on MRI OMIM:614970
Joubert Syndrome 15
Molar tooth sign on MRI OMIM:614464
Joubert Syndrome 28
Molar tooth sign on MRI OMIM:617121
Coach Syndrome 1
Aplasia/Hypoplasia of the cerebellar vermis, Cerebellar vermis hypoplasia, Encephalocele, Occipit... OMIM:216360
Pyruvate Dehydrogenase E3-Binding Protein Deficiency
Abnormal cerebellum morphology, Abnormal brainstem morphology ORPHA:255182
X-Linked Cerebral-Cerebellar-Coloboma Syndrome
Hydrocephalus, Agenesis of cerebellar vermis, Abnormal brainstem morphology, Cerebellar vermis hy... ORPHA:163961
Alpha-N-Acetylgalactosaminidase Deficiency Type 1
Lymphedema, Aplasia/Hypoplasia of the cerebellum, Abnormal brainstem morphology ORPHA:79279
Joubert Syndrome 39
Cerebellar vermis hypoplasia, Occipital encephalocele, Molar tooth sign on MRI OMIM:619562
Joubert Syndrome With Oculorenal Defect
Cerebellar vermis hypoplasia, Hydrocephalus, Molar tooth sign on MRI, Encephalocele ORPHA:2318
Pontocerebellar Hypoplasia Type 10
Abnormal brainstem morphology ORPHA:411493
Coach Syndrome 3
Molar tooth sign on MRI OMIM:619113
Joubert Syndrome With Renal Defect
Cerebellar vermis hypoplasia, Hydrocephalus, Molar tooth sign on MRI, Encephalocele ORPHA:220497
Joubert Syndrome 1
Elongated superior cerebellar peduncle, Dysgenesis of the cerebellar vermis, Agenesis of cerebell... OMIM:213300
Arima Syndrome
Occipital meningocele, Aplasia/Hypoplasia of the cerebellar vermis, Dilated fourth ventricle, Age... OMIM:243910
Joubert Syndrome 37
Cerebellar vermis hypoplasia, Molar tooth sign on MRI OMIM:619185
Joubert Syndrome 8
Occipital encephalocele, Molar tooth sign on MRI OMIM:612291
Neurodevelopmental Disorder With Dysmorphic Facies And Cerebellar Hypoplasia
Rhombencephalosynapsis, Dilated fourth ventricle, Cerebellar hypoplasia, Cerebellar vermis hypopl... OMIM:619306
Joubert Syndrome With Ocular Defect
Cerebellar vermis hypoplasia, Hydrocephalus, Molar tooth sign on MRI, Encephalocele ORPHA:220493
Duplication Of The Pituitary Gland
Polyhydramnios, Encephalocele, Abnormal midbrain morphology ORPHA:314621
Lennox-Gastaut Syndrome
Abnormal brainstem morphology ORPHA:2382
Joubert Syndrome With Jeune Asphyxiating Thoracic Dystrophy
Elongated superior cerebellar peduncle, Abnormal cerebellum morphology, Dysgenesis of the cerebel... ORPHA:397715
Hyperekplexia-Epilepsy Syndrome
Exaggerated startle response ORPHA:163985
Lymphatic Malformation 7
Pulmonary edema, Facial edema, Nonimmune hydrops fetalis, Lymphedema, Edema, Pericardial effusion OMIM:617300
Japanese Encephalitis
Abnormal pons morphology, Pulmonary edema, Abnormal substantia nigra morphology, Abnormal midbrai... ORPHA:79139
Aprosencephaly And Cerebellar Dysgenesis
Poorly formed metencephalon, Aprosencephaly, Cerebellar dysplasia, Absent mesencephalon OMIM:601374
Amoebiasis Due To Free-Living Amoebae
Abnormal pons morphology, Abnormal cerebellum morphology, Abnormal brainstem MRI signal intensity... ORPHA:68
Spinocerebellar Ataxia Type 1
Loss of Purkinje cells in the cerebellar vermis, Atrophy/Degeneration affecting the brainstem, Ce... ORPHA:98755
Cerebellar-Facial-Dental Syndrome
Hypoplasia of the pons, Cerebellar hypoplasia, Inferior cerebellar vermis hypoplasia, Abnormal mi... ORPHA:444072
Posterior Meningocele
Occipital meningocele, Hydrocephalus, Neural tube defect, Chiari malformation, Meningocele, Lipom... ORPHA:268810
Alg3-Cdg
Dandy-Walker malformation, Hypoplasia of the pons, Neural tube defect ORPHA:79321
Fryns Microphthalmia Syndrome
Neural tube defect OMIM:600776
Joubert Syndrome 5
Aplasia/Hypoplasia of the cerebellar vermis, Agenesis of cerebellar vermis, Thickened superior ce... OMIM:610188
Polymicrogyria Due To Tubb2B Mutation
Cerebellar atrophy, Hypoplasia of the pons, Abnormal brainstem morphology ORPHA:300573
Muscle-Eye-Brain Disease With Bilateral Multicystic Leucodystrophy
Cerebellar vermis hypoplasia, Abnormal pons morphology, Cerebellar cyst, Abnormal brainstem morph... ORPHA:370997
Short-Rib Thoracic Dysplasia 13 With Or Without Polydactyly
Encephalocele, Molar tooth sign on MRI, Cerebellar hypoplasia, Dandy-Walker malformation OMIM:616300
Joubert Syndrome 38
Cerebellar vermis hypoplasia, Molar tooth sign on MRI, Inferior cerebellar vermis hypoplasia OMIM:619476
Aromatic L-Amino Acid Decarboxylase Deficiency
Torticollis, Blepharospasm, Exaggerated startle response, Oculogyric crisis, Athetosis, Choreoath... OMIM:608643
Developmental And Epileptic Encephalopathy 68
Exaggerated startle response OMIM:618201
Hyperekplexia 2
Exaggerated startle response OMIM:614619
Familial Acute Necrotizing Encephalopathy
Cerebral edema, Abnormal brainstem morphology, Abnormal brainstem MRI signal intensity ORPHA:88619
Meckel Syndrome, Type 1
Intrauterine growth retardation, Hydrocephalus, Anencephaly, Cerebellar hypoplasia, Large placent... OMIM:249000
Neurodevelopmental Disorder With Microcephaly, Epilepsy, And Hypomyelination
Exaggerated startle response OMIM:618367
47,Xyy Syndrome
Hydrocephalus, Cerebellar dysplasia, Dysgenesis of the cerebellar vermis, Abnormal brainstem morp... ORPHA:8
Blepharocheilodontic Syndrome 1
Neural tube defect OMIM:119580
Orofaciodigital Syndrome Xvi
Molar tooth sign on MRI OMIM:617563
Craniorachischisis
Myelomeningocele, Cervical spina bifida, Anencephaly, Sirenomelia, Spinal dysraphism ORPHA:63260
Gm2 Gangliosidosis, Ab Variant
Dystonia, Exaggerated startle response ORPHA:309246
Oculocerebral Hypopigmentation Syndrome, Preus Type
Hydrocephalus, Aplasia/Hypoplasia of the cerebellum, Abnormal brainstem morphology ORPHA:2720
Cerebellofaciodental Syndrome
Hypoplasia of the pons, Cerebellar hypoplasia, Hypoplasia of the midbrain OMIM:616202
Hyperekplexia 1
Exaggerated startle response OMIM:149400
Wilson Disease
Face of the giant panda sign, Pedal edema, Ascites, Edema OMIM:277900
Orofaciodigital Syndrome Type 6
Cerebellar vermis hypoplasia, Molar tooth sign on MRI ORPHA:2754
Stiff Person Spectrum Disorder
Exaggerated startle response ORPHA:3198
Tay-Sachs Disease
Exaggerated startle response OMIM:272800
Spastic Tetraplegia And Axial Hypotonia, Progressive
Exaggerated startle response OMIM:618598
Gm2-Gangliosidosis, Ab Variant
Dystonia, Exaggerated startle response OMIM:272750
Spastic Paraplegia, Optic Atrophy, And Neuropathy
Exaggerated startle response OMIM:609541
Spastic Paraplegia-Optic Atrophy-Neuropathy Syndrome
Exaggerated startle response ORPHA:320406
Short-Rib Thoracic Dysplasia 21 Without Polydactyly
Molar tooth sign on MRI, Dysgenesis of the cerebellar vermis OMIM:619479
Stiff-Person Syndrome
Exaggerated startle response, Opisthotonus OMIM:184850
Orofaciodigital Syndrome Xiv
Holoprosencephaly, Cerebellar hypoplasia, Occipital encephalocele, Dandy-Walker malformation, Mol... OMIM:615948
Gangliocytoma
Abnormal cerebellum morphology, Abnormal brainstem morphology ORPHA:251937
Familial Cerebral Saccular Aneurysm
Abnormal brainstem morphology ORPHA:231160
Asparagine Synthetase Deficiency
Exaggerated startle response OMIM:615574
Pura-Related Severe Neonatal Hypotonia-Seizures-Encephalopathy Syndrome Due To A Point Mutation
Dystonia, Exaggerated startle response ORPHA:438216
Rapid-Onset Childhood Obesity-Hypothalamic Dysfunction-Hypoventilation-Autonomic Dysregulation Syndrome
Abnormal midbrain morphology ORPHA:293987
Tay-Sachs Disease
Tremor, Dystonia, Exaggerated startle response, Laryngeal dystonia ORPHA:845
Glycine Encephalopathy With Normal Serum Glycine
Exaggerated startle response OMIM:617301
Leigh Syndrome With Cardiomyopathy
Abnormal brainstem morphology ORPHA:70474
Sandhoff Disease
Exaggerated startle response OMIM:268800
Orofaciodigital Syndrome Type 14
Dilated fourth ventricle, Molar tooth sign on MRI, Dandy-Walker malformation ORPHA:434179
Intellectual Disability Syndrome Due To A Dyrk1A Point Mutation
Polyhydramnios, Oligohydramnios, Intrauterine growth retardation, Abnormal brainstem morphology ORPHA:464311
Plaa-Associated Neurodevelopmental Disorder
Dystonia, Exaggerated startle response ORPHA:521426
Fragile X-Associated Tremor/Ataxia Syndrome
Diffuse cerebellar atrophy, Abnormal brainstem morphology ORPHA:93256
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain And Eye Anomalies), Type A, 4
Exaggerated startle response OMIM:253800
Gm1 Gangliosidosis Type 1
Exaggerated startle response ORPHA:79255
Neurodevelopmental Disorder With Progressive Microcephaly, Spasticity, And Brain Anomalies
Exaggerated startle response OMIM:617527
Semilobar Holoprosencephaly
Neural tube defect, Hydrocephalus, Abnormal brainstem morphology ORPHA:220386
Alobar Holoprosencephaly
Neural tube defect, Hydrocephalus, Abnormal brainstem morphology ORPHA:93925
Midline Interhemispheric Variant Of Holoprosencephaly
Neural tube defect, Hydrocephalus, Abnormal brainstem morphology ORPHA:93926
Lobar Holoprosencephaly
Neural tube defect, Hydrocephalus, Abnormal brainstem morphology ORPHA:93924
Schinzel-Giedion Syndrome
Chiari type I malformation, Neural tube defect, Umbilical hernia ORPHA:798
Pura-Related Severe Neonatal Hypotonia-Seizures-Encephalopathy Syndrome
Exaggerated startle response, Dystonia ORPHA:438213
Neurodevelopmental-Craniofacial Syndrome With Variable Renal And Cardiac Abnormalities
Exaggerated startle response OMIM:619522

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Laptm4b

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Laptm4b.

No publications found that use IMPC mice or data for Laptm4b.

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MGI Allele Allele Type Produced
Laptm4btm1e.1(KOMP)Wtsi Promoter excision from Targeted, non-conditional allele Mice, Tissue
Laptm4btm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Laptm4btm1e(KOMP)Wtsi Targeted, non-conditional allele Mice, ES Cells

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