Gene: Laptm4b

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Name
lysosomal-associated protein transmembrane 4B
MGI ID
MGI:1890494
Synonyms
C330023P13Rik
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal midbrain morphology Laptm4btm1e.1(KOMP)Wtsi HOM E12.5 0.00
abnormal eye morphology Laptm4btm1e.1(KOMP)Wtsi HOM E12.5 0.00
abnormal neural tube closure Laptm4btm1e.1(KOMP)Wtsi HOM E12.5 0.00
abnormal hindbrain morphology Laptm4btm1e.1(KOMP)Wtsi HOM E12.5 0.00
abnormal embryo size Laptm4btm1e.1(KOMP)Wtsi HOM E12.5 0.00
decreased prepulse inhibition Laptm4btm1e.1(KOMP)Wtsi HET Early adult 2.69×10-09
edema Laptm4btm1e.1(KOMP)Wtsi HOM E15.5 0.00
preweaning lethality, incomplete penetrance Laptm4btm1e.1(KOMP)Wtsi HOM Early adult 0.00
abnormal craniofacial morphology Laptm4btm1e.1(KOMP)Wtsi HOM E15.5 0.00

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 0  (1/61) N/A
Brain 3  (6/504) N/A
Central nervous system ganglion 0  (1/70) N/A
Ear 3  (1/504) N/A
Embryo 3  (1/505) N/A
Eye 3  (1/504) N/A
Foot 3  (1/504) N/A
Forebrain 3  (1/504) N/A
Forelimb 3  (1/504) N/A
Gut 0  (1/56) N/A
Hand 3  (1/503) N/A
Head 3  (5/504) N/A
Heart 3  (1/504)  (2/8) N/A
Hindbrain 3  (6/504) N/A
Hindlimb 3  (1/503) N/A
Liver 3  (1/504)  (2/8) N/A
Lung 3  (1/500) N/A
Mandibular process 3  (1/504) N/A
Maxillary process 3  (1/504) N/A
Midbrain 3  (1/504) N/A
Nose 0  (1/70) N/A
Oral cavity 3  (1/504) N/A
0  (7/37)  (2/2) N/A
Skeleton 0  (1/70) N/A
Skin 3  (1/504) N/A
Spinal cord 0  (1/69) N/A
Tail 3  (1/504) N/A
Tail somite 3  (1/504) N/A
Trachea 0  (1/56) N/A
Urinary system 0  (1/56)  (2/2) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
32 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Gross Morphology Embryo E14.5-E15.5
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Laptm4btm1e.1(KOMP)Wtsi Mice, Tissue
Laptm4btm1e(KOMP)Wtsi Targeted, non-conditional allele Mice
Laptm4btm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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