Genes Phenotypes

Gene: Foxo1

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Name
forkhead box O1
MGI ID
MGI:1890077
Synonyms
Afxh Fkhr1 FKHR Foxo1a
Viability
Homozygous - Lethal
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (64) All data table (283)
Expression & images (73) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Foxo1tm1b(EUCOMM)Wtsi HOM n/a 0.00
embryonic growth retardation Foxo1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal hindbrain development Foxo1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal embryo size Foxo1tm1b(EUCOMM)Wtsi HET embryonic day 9.5 0.00
abnormal midbrain development Foxo1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
embryonic growth retardation Foxo1tm1b(EUCOMM)Wtsi HET embryonic day 9.5 0.00

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Section images
Aorta 2 No  (2/2)  Section images
Brain 2 No  (2/2)  Section images
Brainstem 2 No  (2/2)  Section images
Brown adipose tissue 2 No  (2/2)  Section images
Cartilage tissue 2 No  (2/2)  Section images
Cerebellum 2 No  (2/2)  Section images
Cerebral cortex 2 No  (2/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/2)  Section images
Hippocampus 2 No  (2/2)  Section images
Hypothalamus 2 No  (2/2)  Section images
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584)  (2/2)  Section images
Liver 2 No  (1/2)  Section images
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Section images
Lymph node 2 No  (2/2)  Section images
Mammary gland 2 No  (1/2)  Section images
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/2)  Section images
Ovary 2 No  (1/584)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/584)  (2/2)  Section images
Peripheral nervous system 2 No  (2/2)  Section images
Peyer's patch 2 No  (2/2)  Section images
Pituitary gland 2 No  (2/2)  Section images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No  Section images
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/584)  (2/2)  Section images
Spinal cord 2 No  (2/2)  Section images
Spleen 2 No  (2/584)  (2/2)  Section images
Stomach 2 No  (12/584)  (2/2)  Section images
Striatum 2 No  (2/2)  Section images
Submandibular gland 2 No  (2/132)  (2/2)  Section images
Testis 2 No  (2/584)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  (2/2)  Section images
Thyroid gland 2 No  (15/584)  (2/2)  Section images
Trachea 2 No  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2)  Section images
LacZ Wholemount Images
LacZ Section Images
adipose tissue (2)
Brown adipose tissue expression
MA:0000057
cardiovascular system (3)
Aorta expression
MA:0000062
digestive system (7)
Esophagus expression
MA:0000352
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (2)
Mammary gland expression
MA:0000145
immune system (4)
Lymph Node expression
MA:0000139
integumental system (2)
Mammary gland expression
MA:0000145
musculoskeletal system (1)
Skeletal Muscle imageOnly
MA:0003148
nervous system (13)
Brain expression
MA:0000168
postnatal mouse (45)
Adrenal gland expression
MA:0000116
reproductive system (5)
Epididymis expression
MA:0000397
respiratory system (3)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (3)
Brown adipose tissue expression
MA:0000057
trunk (22)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485)  (1/1) N/A
Dorsal root ganglion 1  (1/47)  (1/1) N/A
Ear 1  (1/485) Image Only N/A
Embryo 1  (1/485)  (1/1)  Wholemount images
Eye 1  (1/485)  (1/1) N/A
Foot 1  (1/485)  (1/1) N/A
Forebrain 1  (1/485)  (1/1) N/A
Forelimb 1  (1/485)  (1/1) N/A
Fronto-nasal process 1  (1/48) Image Only N/A
Hand 1  (1/485)  (1/1) N/A
Head 1  (5/485)  (1/1) N/A
Heart 1  (1/485)  (1/1) N/A
Hindbrain 1  (6/485)  (1/1) N/A
Hindlimb 1  (1/485)  (1/1) N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) Image Only N/A
Mandibular process 1  (1/485)  (1/1) N/A
Maxillary process 1  (1/485)  (1/1) N/A
Midbrain 1  (1/485)  (1/1) N/A
Nose 1  (1/51)  (1/1) N/A
Oral cavity 1  (1/485) Image Only N/A
Skin 1  (1/485)  (1/1) N/A
Spinal cord 1  (1/50)  (1/1) N/A
Tail 1  (1/485)  (1/1) N/A
Tail somite 1  (1/485) Image Only N/A
embryo or Unassigned (4)
Embryo expression
EMAPA:16039 embryo

 Associated Images

Gross Morphology Embryo E9.5
10 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Original Image
Adult LacZ: LacZ Images Section
45 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
4 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Foxo1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Foxo1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Foxo1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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