Sncb | synuclein, beta

GeneMGI:1889011Synonyms: betaSYN

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Skeleton

17 No significant impact

5 Not tested

Gene metrics:3Significant phenotypes
1Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues

Phenotypes

decreased bone mineral content2 supporting datasetsSncbtm1b(EUCOMM)HmguhomozygoteEarly adult1.15x10-9 
abnormal bone structure1 supporting datasetSncbtm1b(EUCOMM)HmguhomozygoteEarly adult2.55x10-6 
impaired glucose tolerance1 supporting datasetSncbtm1b(EUCOMM)HmguhomozygoteEarly adult7.7x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sncbtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Sncbtm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Sncbtm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Sncbtm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Sncbtm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Sncbtm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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