Genes Phenotypes

Gene: Rexo2

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Name
RNA exonuclease 2
MGI ID
MGI:1888981
Synonyms
1810038D15Rik Rex2 Smfn Sfn
Viability
Homozygous - Lethal
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (217) All data table (333)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating cholesterol level Rexo2tm1b(EUCOMM)Wtsi HET postnatal 9.23×10-07
decreased fasted circulating glucose level Rexo2tm1b(EUCOMM)Wtsi HET postnatal 8.93×10-10
increased circulating HDL cholesterol level Rexo2tm1b(EUCOMM)Wtsi HET postnatal 1.38×10-08
preweaning lethality, complete penetrance Rexo2tm1b(EUCOMM)Wtsi HOM n/a 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No  (1/2)  Wholemount images
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (1/2)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (3)
Heart expression
Aorta expression
MA:0000072
MA:0000062
digestive system (4)
Gall Bladder expression
MA:0000356
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (2)
Mammary gland expression
MA:0000145
integumental system (2)
Mammary gland expression
MA:0000145
musculoskeletal system (1)
Vascular System expression
Cartilage tissue expression
Bone expression
MA:0002718
MA:0000104
MA:0001459
nervous system (5)
Brain expression
Hippocampus expression
Striatum expression
Cerebral Cortex expression
MA:0000168
MA:0000191
MA:0000891
MA:0000185
postnatal mouse (23)
Adrenal gland expression
MA:0000116
reproductive system (3)
Ovary expression
Oviduct expression
Uterus expression
MA:0000384
MA:0000385
MA:0000389
respiratory system (2)
Cartilage tissue expression
Trachea expression
Parathyroid gland expression
Thyroid gland expression
MA:0000104
MA:0000441
MA:0000128
MA:0000129
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (2)
Cartilage tissue expression
Trachea expression
Parathyroid gland expression
Thyroid gland expression
MA:0000104
MA:0000441
MA:0000128
MA:0000129
trunk (14)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (2/2) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/2) N/A
Eye 2  (1/485)  (2/2) N/A
Foot 2  (1/485) Image Only N/A
Forebrain 2  (1/485)  (2/2) N/A
Forelimb 2  (1/485)  (2/2) N/A
Hand 2  (1/485) Image Only N/A
Head 2  (5/485)  (2/2) N/A
Heart 2  (1/485) Image Only N/A
Hindbrain 2  (6/485)  (2/2) N/A
Hindlimb 2  (1/485)  (2/2) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485)  (2/2) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Tail 2  (1/485)  (2/2) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
10 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Adult LacZ: LacZ Images Wholemount
23 Images
Embryo LacZ: LacZ images wholemount
4 Images
X-ray: XRay Images Dorso Ventral
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Rexo2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Rexo2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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