Gene: Cyp2c23

Name
cytochrome P450, family 2, subfamily c, polypeptide 23
MGI ID
MGI:1888897
Synonyms
Cyp2c44
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Bulging eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / RR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.943 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Iris/Pupil HOM 8f:8m Fisher Exact Test framework 0.312 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Mean cell hemoglobin concentration HOM 4f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.697 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Mean cell hemoglobin concentration HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Corneal deposits HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Open Field / Percentage center time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.540 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Eosinophil differential count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Mean platelet volume HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 3f:2m 0.325 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 0f:2m 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Body length HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.961 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Urinalysis / Magnesium HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0807 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Lens Opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Open Field / Periphery distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.315 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Light-Dark Test / Dark side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0735 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Sleep Wake / Sleep light phase percent HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0142 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Hematocrit HOM 4f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.0948 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Hematocrit HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.166 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.359 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Pupil Dilation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Fat mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.138 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.707 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 3f:2m 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 0f:2m 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Tremor HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Viability Primary Screen / Outcome HOM 18f:13m Supplied as data Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Large Unstained Cell (LUC) count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Lymphocyte cell count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Sleep Wake / Light sleep bout lengths mean HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.437 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / ST HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.635 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Open Field / Center distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.784 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 3f:2m 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 0f:2m 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Light-Dark Test / Percent time in dark HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0813 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Corneal vascularization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / PQ HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0643 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Sleep Wake / Light sleep bout lengths standard deviation HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.162 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Platelet count HOM 4f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.000230 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Platelet count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Pupil Position HOM 8f:8m Fisher Exact Test framework 0.333 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.224 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Eyelid closure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Light-Dark Test / Time mobile light side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.268 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Sleep Wake / Breath rate during sleep standard deviation HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00716 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Iris transilumination HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Eosinophil cell count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Urinalysis / Albumin to Creatinine ratio HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 1.31×10-05 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0387 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Hemoglobin HOM 4f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.535 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Hemoglobin HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Open Field / Whole arena resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.448 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Vitreous HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Lens HOM 8f:8m Fisher Exact Test framework 0.00984 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / QTc HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.543 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0440 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Head size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Open Field / Center average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.218 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Narrow eye opening HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Sleep Wake / Sleep dark phase percent HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.340 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Heart Weight / Heart weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.702 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.661 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Neutrophil differential count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Persistence of hyaloid vascular system HOM 8f:8m Fisher Exact Test framework 0.698 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.517 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00520 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Pupil Shape HOM 8f:8m Fisher Exact Test framework 0.237 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Light-Dark Test / Latency to first transition into dark HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.523 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / QTc Dispersion HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00917 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Open Field / Periphery average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.380 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Sleep Wake / Dark sleep bout lengths standard deviation HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.588 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Lymphocyte differential count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Monocyte differential count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Light-Dark Test / Percent time in light HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0813 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0225 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / rMSSD HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0224 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Open Field / Distance travelled - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.256 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Snout size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / PR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.743 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Sleep Wake / Dark sleep bout lengths mean HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.813 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Synechia HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 3f:2m 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 0f:2m 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Light-Dark Test / Light side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0735 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Open Field / Periphery permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.540 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.566 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / HR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.952 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Aggression HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Grip Strength / Forelimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0711 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Startle response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Eyelid morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Mean cell volume HOM 4f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.0536 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Mean cell volume HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Sleep Wake / Sleep daily percent HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.124 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 0.239 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Open Field / Center permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.540 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 3f:2m 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 0f:2m 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Basophil cell count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.484 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Red blood cell count HOM 4f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.627 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Red blood cell count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.704 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Urinalysis / Creatinine HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.240 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Light-Dark Test / Fecal boli HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0245 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Iris Pigmentation HOM 8f:8m Fisher Exact Test framework 0.0476 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / HRV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0437 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Sleep Wake / Breath rate during sleep mean HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.408 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0221 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Sleep Wake / Sleep bout lengths mean HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.514 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Neutrophil cell count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:8m Fisher Exact Test framework 0.00262 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Urinalysis / Glucose HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.230 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Light-Dark Test / Side changes HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0838 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Corneal Sclerization HOM 8f:8m Fisher Exact Test framework 0.197 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hole-board Exploration / Total holepokes HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.905 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Monocyte cell count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Open Field / Number of rears - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.781 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Bone Area HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.807 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Fusion between cornea and lens HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Mean corpuscular hemoglobin HOM 4f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.107 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Mean corpuscular hemoglobin HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.716 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Large Unstained Cell (LUC) differential count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / CV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0496 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0405 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Basophil differential count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Sleep Wake / Peak wake with respect to dark onset median HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.408 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Light-Dark Test / Time mobile dark side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.749 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Urinalysis / microAlbumin (calculated) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0252 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Gait HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Electrocardiogram (ECG) / QRS HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.605 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / Red blood cell distribution width HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Ears HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Body Composition (DEXA lean/fat) / Lean mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.685 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Pupil Light Response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Open Field / Whole arena average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.254 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Sleep Wake / Sleep bout lengths standard deviation HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.233 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / White blood cell count HOM 4f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.793 Success
Cyp2c23tm1b(EUCOMM)Hmgu JAX Hematology / White blood cell count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Cyp2c23tm1b(EUCOMM)Hmgu JAX Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Section images
Striatum 2 No N/A
Submandibular gland 2 No  (2/132)  (1/2)  Section images
Testis 2 No  (2/584)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Dorsal root ganglion 1  (1/47) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Fronto-nasal process 1  (1/48) N/A
Hand 2  (1/485) N/A
Head 2  (5/485) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Nose 1  (1/51) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Spinal cord 1  (1/50) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Original Image
Adult LacZ: LacZ Images Section
4 Images
X-ray: XRay Images Dorso Ventral
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Cyp2c23tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Cyp2c23tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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