Gene: Heyl

Name
hairy/enhancer-of-split related with YRPW motif-like
MGI ID
MGI:1860511
Synonyms
bHLHb33 Hey3 Hrt3 Hesr3
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (226) Expression & images (74) Disease models (0) Order (4)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Alanine aminotransferase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.142 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Bulging eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / RR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.330 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Iris/Pupil HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Corneal deposits HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Open Field / Percentage center time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.223 Success
Heyltm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Body length HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.100 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Lens Opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Open Field / Periphery distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0308 Success
Heyltm1b(KOMP)Wtsi JAX Light-Dark Test / Dark side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.695 Success
Heyltm1b(KOMP)Wtsi JAX Sleep Wake / Sleep light phase percent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.620 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
Heyltm1b(KOMP)Wtsi JAX Tail Suspension / Latency to immobility HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.288 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Calcium HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.455 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0983 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.529 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Rotarod / Learning slope HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.276 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Pupil Dilation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Potassium HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0206 Success
Heyltm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 6f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.174 Success
Heyltm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Fat mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.990 Success
Heyltm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Phosphorus HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.254 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Tremor HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Viability Primary Screen / Outcome HOM 24f:30m Supplied as data Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Sleep Wake / Light sleep bout lengths mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.300 Success
Heyltm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / ST HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.458 Success
Heyltm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod b-wave amplitude HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Open Field / Center distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.489 Success
Heyltm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Light-Dark Test / Percent time in dark HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.453 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Corneal vascularization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Triglycerides HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.890 Success
Heyltm1b(KOMP)Wtsi JAX Sleep Wake / Light sleep bout lengths standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.628 Success
Heyltm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / PQ HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.860 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Total protein HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00529 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Pupil Position HOM 8f:8m Fisher Exact Test framework 0.333 Success
Heyltm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.755 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Eyelid closure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Light-Dark Test / Time mobile light side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.259 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Sleep Wake / Breath rate during sleep standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.495 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Iris transilumination HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Aspartate aminotransferase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0995 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Tail Suspension / Time immobile HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.900 Success
Heyltm1b(KOMP)Wtsi JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.371 Success
Heyltm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod b-wave amplitude-left HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Open Field / Whole arena resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0230 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Vitreous HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Lens HOM 8f:8m Fisher Exact Test framework 0.593 Success
Heyltm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / QTc HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.736 Success
Heyltm1b(KOMP)Wtsi JAX Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.339 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Head size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Open Field / Center average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.150 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Narrow eye opening HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Sodium HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000158 Success
Heyltm1b(KOMP)Wtsi JAX Sleep Wake / Sleep dark phase percent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00531 Success
Heyltm1b(KOMP)Wtsi JAX Heart Weight / Heart weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00675 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.336 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / HDL-cholesterol HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00248 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Persistence of hyaloid vascular system HOM 8f:8m Fisher Exact Test framework 0.448 Success
Heyltm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 6f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.468 Success
Heyltm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 6f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.125 Success
Heyltm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Pupil Shape HOM 8f:8m Fisher Exact Test framework 0.237 Success
Heyltm1b(KOMP)Wtsi JAX Light-Dark Test / Latency to first transition into dark HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.801 Success
Heyltm1b(KOMP)Wtsi JAX Open Field / Periphery average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.141 Success
Heyltm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / QTc Dispersion HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.539 Success
Heyltm1b(KOMP)Wtsi JAX Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Sleep Wake / Dark sleep bout lengths standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.140 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Light-Dark Test / Percent time in light HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.453 Success
Heyltm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00386 Success
Heyltm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / rMSSD HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.574 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Open Field / Distance travelled - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0366 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Snout size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Sleep Wake / Dark sleep bout lengths mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.496 Success
Heyltm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / PR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.885 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Synechia HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Iron HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.942 Success
Heyltm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Total cholesterol HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00396 Success
Heyltm1b(KOMP)Wtsi JAX Light-Dark Test / Light side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.695 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Open Field / Periphery permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.223 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Albumin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.188 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / HR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.383 Success
Heyltm1b(KOMP)Wtsi JAX Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.756 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Aggression HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod b-wave amplitude-right HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Grip Strength / Forelimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.633 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Startle response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Eyelid morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Sleep Wake / Sleep daily percent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0120 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Free fatty acids HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.140 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 0.239 Success
Heyltm1b(KOMP)Wtsi JAX Open Field / Center permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.223 Success
Heyltm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.291 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0499 Success
Heyltm1b(KOMP)Wtsi JAX Light-Dark Test / Fecal boli HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.102 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Iris Pigmentation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Sleep Wake / Breath rate during sleep mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.000710 Success
Heyltm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / HRV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.464 Success
Heyltm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 6f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.000646 Success
Heyltm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Sleep Wake / Sleep bout lengths mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.348 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod a-wave amplitude-right HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Rotarod / Average duration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.644 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.716 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Light-Dark Test / Side changes HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.822 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Corneal Sclerization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Alkaline phosphatase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0248 Success
Heyltm1b(KOMP)Wtsi JAX Hole-board Exploration / Total holepokes HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.355 Success
Heyltm1b(KOMP)Wtsi JAX Electroretinography 2 / Cone b-wave amplitude HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Open Field / Number of rears - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.317 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Bone Area HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.215 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Fusion between cornea and lens HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod b-wave implicit time HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0101 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Total bilirubin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0324 Success
Heyltm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / CV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.384 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Electroretinography 2 / Cone b-wave amplitude-left HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0818 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Electroretinography 2 / Cone b-wave amplitude-right HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Sleep Wake / Peak wake with respect to dark onset median HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.529 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Glucose HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.000116 Success
Heyltm1b(KOMP)Wtsi JAX Light-Dark Test / Time mobile dark side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.715 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Heyltm1b(KOMP)Wtsi JAX Tail Suspension / Climbing HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Gait HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod a-wave implicit time HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Electrocardiogram (ECG) / QRS HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.800 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Ears HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod a-wave amplitude HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Insulin Blood Level / Insulin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0124 Success
Heyltm1b(KOMP)Wtsi JAX Clinical Chemistry / Chloride HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0538 Success
Heyltm1b(KOMP)Wtsi JAX Rotarod / Learning difference HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.195 Success
Heyltm1b(KOMP)Wtsi JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 2f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Body Composition (DEXA lean/fat) / Lean mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.215 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Pupil Light Response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Open Field / Whole arena average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0364 Success
Heyltm1b(KOMP)Wtsi JAX Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Heyltm1b(KOMP)Wtsi JAX Sleep Wake / Sleep bout lengths standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0634 Success
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Heyltm1b(KOMP)Wtsi JAX Electroretinography 2 / Rod a-wave amplitude-left HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Heyltm1b(KOMP)Wtsi JAX Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No  (1/2) N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (2/3) N/A
Central nervous system ganglion 1  (1/51)  (1/1) N/A
Dorsal root ganglion 2  (1/47)  (2/3) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/3)  Wholemount images
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485)  (2/3) N/A
Forelimb 2  (1/485)  (1/3) N/A
Fronto-nasal process 2  (1/48) Image Only N/A
Hand 2  (1/485) N/A
Head 2  (5/485)  (2/3) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485)  (2/3) N/A
Hindlimb 2  (1/485)  (1/3) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) Image Only N/A
Mandibular process 2  (1/485)  (1/3) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485)  (2/3) N/A
Nose 2  (1/51) N/A
Oral cavity 2  (1/485) Image Only N/A
Skin 2  (1/485) Image Only N/A
Spinal cord 2  (1/50)  (2/3) N/A
Tail 2  (1/485)  (2/3) N/A
Tail somite 2  (1/485)  (1/3) N/A

 Associated Images

Sleep Wake: Wake state (bmp file)
16 Images
Electroretinography 2: Rod and cone PDF
4 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Heyltm301368(L1L2_Bact_P) Targeting vectors
Heyltm36687(L1L2_gt2) Targeting vectors
Heyltm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Heyltm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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