Gene: Gtpbp2

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Phenotype System Allele Zyg Sex Life Stage P Value
enlarged lymph nodes Gtpbp2tm1b(KOMP)Mbp HET Early adult 0.00
enlarged lymph nodes Gtpbp2tm1b(KOMP)Mbp HOM Early adult 0.00
increased exploration in new environment Gtpbp2tm1b(KOMP)Mbp HOM   Early adult 4.42×10-06
preweaning lethality, incomplete penetrance Gtpbp2tm1b(KOMP)Mbp HOM   Early adult 0.00
hyperactivity Gtpbp2tm1b(KOMP)Mbp HOM   Early adult 6.98×10-12

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Brain 2 No  (4/583)  (2/2)  Section images
Brainstem 2 No  (2/583)  (1/2)  Section images
Cartilage tissue 2 No  (1/583) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Esophagus 2 No  (7/407) N/A
Eye 2 No  (1/2)  Section images
Heart 2 No  (2/583) N/A
Hippocampus 2 No  (3/583)  (2/2)  Section images
Hypothalamus 2 No  (2/583)  (1/2) N/A
Kidney 2 No  (21/583)  (1/2) N/A
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/583) N/A
Ovary 2 No  (1/583) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583) N/A
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583) N/A
Striatum 2 No  (3/583)  (1/2) N/A
Testis 2 No  (6/583)  (1/2) N/A
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Hind Leg and Hip
23 Images
X-ray: XRay Images Whole Body Lateral Orientation
46 Images
Adult LacZ: LacZ Images Section
11 Images
X-ray: XRay Images Whole Body Dorso Ventral
23 Images
Gross Pathology and Tissue Collection
16 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
23 Images
Histopathology
7 Images

 Disease Models

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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Gtpbp2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Gtpbp2tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Gtpbp2tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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