Gene: Crlf3

Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
thrombocytopenia Crlf3em1(IMPC)Wtsi HOM postnatal 1.34×10-17
decreased circulating magnesium level Crlf3tm1b(KOMP)Wtsi HOM postnatal 7.40×10-05
thrombocytopenia Crlf3tm1b(KOMP)Wtsi HOM postnatal 9.76×10-11
increased red blood cell distribution width Crlf3em1(IMPC)Wtsi HOM postnatal 1.97×10-09
decreased mean corpuscular volume Crlf3tm1b(KOMP)Wtsi HOM postnatal 1.86×10-05
decreased body weight Crlf3tm1a(KOMP)Wtsi HOM postnatal 5.93×10-22
increased T cell number Crlf3tm1a(KOMP)Wtsi HOM postnatal 4.69×10-12
decreased NK cell number Crlf3tm1b(KOMP)Wtsi HOM postnatal 8.06×10-05
thrombocytopenia Crlf3tm1a(KOMP)Wtsi HOM postnatal 3.49×10-12

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Select physiological systems to view:
Viewing: all phenotypes


IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 3 No  (2/584)  (3/3) N/A
Aorta 3 No N/A
Blood vessel 3 No N/A
Bone 3 No N/A
Brain 3 No  (3/3) N/A
Brainstem 3 No N/A
Brown adipose tissue 3 No N/A
Cartilage tissue 3 No  (3/3) N/A
Cerebellum 3 No N/A
Cerebral cortex 3 No N/A
Eye 3 No N/A
Gall bladder 3 No N/A
Heart 3 No  (3/3) N/A
Hippocampus 3 No N/A
Hypothalamus 3 No N/A
Kidney 3 No  (18/584)  (3/3) N/A
Large intestine 3 No  (10/584)  (1/3) N/A
Liver 3 No N/A
Lower urinary tract 3 No  (2/3) N/A
Lung 3 No  (3/3) N/A
Lymph node 3 No  (3/3) N/A
Mammary gland 3 No N/A
Esophagus 3 No  (1/3) N/A
Olfactory lobe 3 No N/A
Ovary 3 No  (1/584)  (2/3) N/A
Oviduct 3 No  (2/3) N/A
Pancreas 3 No  (5/584) N/A
Parathyroid gland 3 No  (1/3) N/A
Peripheral nervous system 3 No  (3/3) N/A
Peyer's patch 3 No  (3/3) N/A
Pituitary gland 3 No N/A
Prostate gland 3 No  (12/584) N/A
Skeletal muscle tissue 3 No N/A
Skin 3 No  (3/3) N/A
Small intestine 3 No  (9/584)  (2/3) N/A
Spinal cord 3 No  (3/3) N/A
Spleen 3 No  (2/584)  (3/3) N/A
Stomach 3 No  (12/584)  (1/3) N/A
Striatum 3 No N/A
Testis 3 No  (2/584)  (1/3) N/A
Thymus 3 No  (3/3) N/A
Thyroid gland 3 No  (15/584)  (1/3) N/A
Trachea 3 No  (3/3) N/A
Uterus 3 No  (2/3) N/A
White adipose tissue 3 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Forepaw
23 Images
X-ray: XRay Images Dorso Ventral
69 Images
X-ray: XRay Images Lateral Orientation
46 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
23 Images
X-ray: XRay Images Skull Lateral Orientation
23 Images
Anti-nuclear antibody assay
6 Images
DSS Histology
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Crlf3tm1c(KOMP)Wtsi Wild type floxed exon (post-Flp) Mice
Crlf3tm38187(L1L2_Bact_P) Targeting vectors
Crlf3tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Crlf3em1(IMPC)Wtsi Exdel Mice
Crlf3tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Crlf3tm356713(L1L2_Bact_P) Targeting vectors

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