Rnf5 | ring finger protein 5

GeneMGI:1860076Synonyms: 2410131O05Rik

Physiological systems

23 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Immune system Integument Endocrine/exocrine gland Growth/size/body region Liver/biliary system Hematopoietic system Behavior/neurological Mortality/aging

15 No significant impact

1 Not tested

Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:78Adult tissues
0Embryo tissues

Phenotypes

enlarged thymus1 supporting datasetRnf5tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance1 supporting datasetRnf5tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
no spontaneous movement1 supporting datasetRnf5tm1.1(KOMP)VlcghomozygoteE18.5N/A * 
abnormal skin morphology1 supporting datasetRnf5tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetRnf5tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
enlarged gallbladder1 supporting datasetRnf5tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
abnormal gallbladder morphology1 supporting datasetRnf5tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetRnf5tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
increased freezing behavior1 supporting datasetRnf5tm1.1(KOMP)VlcgheterozygoteEarly adult9.72x10-6 
abnormal spleen morphology1 supporting datasetRnf5tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rnf5tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Rnf5tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Rnf5tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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