Gene: Ppt2

Name
palmitoyl-protein thioesterase 2
MGI ID
MGI:1860075
Synonyms
0610007M19Rik
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

Mouseover the data points for more information. Click and drag to zoom the chart. Click on the legends to disable/enable data.

Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Alanine aminotransferase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.845 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Bulging eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Creatinine HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00303 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Iris/Pupil HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Mean cell hemoglobin concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.512 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Radius HOM 4f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Fibula HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Eosinophil differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0620 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Mean platelet volume HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.439 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Open Field / Percentage center time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.978 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Shape of vertebrae HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Brachydactyly HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Scapulae HOM 5f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Lens Opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Open Field / Periphery distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.596 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Zygomatic bone HOM 5f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Calcium HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.400 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Shape of ribs HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Hematocrit HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.285 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.330 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.476 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Creatine kinase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.731 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Pupil Dilation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Potassium HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0270 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Fat mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0350 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.778 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 1f:2m 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Phosphorus HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.267 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tremor HOM 8f:8m Fisher Exact Test framework 0.198 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Viability Primary Screen / Outcome HOM 99f:95m Supplied as data Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Large Unstained Cell (LUC) count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00347 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Lymphocyte cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0287 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Indirect Calorimetry / Respiratory Exchange Ratio HOM 0f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.860 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Open Field / Center distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.701 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Corneal vascularization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Triglycerides HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.881 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Clavicle HOM 5f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Platelet count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0151 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Digit integrity HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Total protein HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.653 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Pupil Position HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0121 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Open Field / Latency to center entry HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.894 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Eyelid closure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Fusion of vertebrae HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Tibia HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Aspartate aminotransferase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.507 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Eosinophil cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.131 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0337 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Hemoglobin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.831 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Open Field / Whole arena resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.483 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Syndactylism HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Lens HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0827 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Head size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Open Field / Center average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.570 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Narrow eye opening HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Sodium HOM 8f:8m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_CBC_001_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Ppt2tm2b(KOMP)Wtsi MRC Harwell Organ Weight / Heart weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0548 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0816 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Neutrophil differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.714 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / HDL-cholesterol HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.397 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Persistence of hyaloid vascular system HOM 8f:8m Fisher Exact Test framework 0.180 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.704 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.463 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Pupil Shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Open Field / Periphery average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.614 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Processes on vertebrae HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Maxilla/Pre-maxilla HOM 5f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Lymphocyte differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.818 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Monocyte differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.254 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.116 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Number of ribs right HOM 4f:5m 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Open Field / Distance travelled - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.589 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Snout size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Alpha-amylase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.241 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:2m 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Synechia HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Iron HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.295 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Total cholesterol HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.241 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Open Field / Periphery permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.910 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Albumin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0354 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0567 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Aggression HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Open Field / Number of center entries HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.977 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Pelvis HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Grip Strength / Forelimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0696 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Startle response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Eyelid morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Mean cell volume HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.140 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Femur HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Open Field / Center permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.978 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 1f:2m 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Basophil cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.820 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.286 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.385 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Red blood cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.846 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Iris Pigmentation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.841 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Organ Weight / Right kidney HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.166 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Mandibles HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Neutrophil cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.768 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Humerus HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:8m Fisher Exact Test framework 0.154 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Number of digits HOM 4f:5m 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.000319 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Open Field / Periphery resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.605 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Ulna HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Organ Weight / Spleen weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.404 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Fructosamine HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.162 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Alkaline phosphatase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.946 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Monocyte cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.741 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Teeth HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.719 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Number of ribs left HOM 4f:5m 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Bone Area HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.147 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Fusion between cornea and lens HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Mean corpuscular hemoglobin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.736 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00253 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Large Unstained Cell (LUC) differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0124 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Total bilirubin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0175 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Fusion of ribs HOM 4f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.294 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Basophil differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.728 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Open Field / Center resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.767 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Glucose HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0270 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Joints HOM 4f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Skull shape HOM 5f:5m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Gait HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / Red blood cell distribution width HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0258 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Ears HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Ppt2tm2b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Chloride HOM 8f:8m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_CBC_003_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Ppt2tm2b(KOMP)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.771 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Lean mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0232 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell X-ray / Tibia length HOM 4f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.379 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Pupil Light Response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Open Field / Whole arena average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.590 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Organ Weight / Left kidney HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.263 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Hematology / White blood cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0427 Success
Ppt2tm2b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (1/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (1/2)  Wholemount images
Esophagus 2 No  (7/415)  (1/2)  Wholemount images
Eye 2 No  (1/2)  Wholemount images
Gall bladder 2 No  (1/2)  Wholemount images
Heart 2 No  (1/2)  Wholemount images
Hippocampus 2 No  (1/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (1/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No  (1/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (1/2)  Wholemount images
Oral epithelium 2 No  (1/2)  Wholemount images
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (1/2)  Wholemount images
Striatum 2 No  (1/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Dorso Ventral
11 Images
X-ray: XRay Images Lateral Orientation
11 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
5 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
3 Images
Adult LacZ: LacZ Images Wholemount
20 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Ppt2tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ppt2tm2b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Ppt2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Ppt2tm208467(L1L2_Pgk_P) Targeting vectors
Ppt2tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter