Genes Phenotypes

Gene: Atxn10

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Name
ataxin 10
MGI ID
MGI:1859293
Synonyms
Sca10 TEG-169 Tex169 E46
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (5) Measurements chart (290) All data table (981)
Expression & images (45) Disease models (0) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
prenatal lethality prior to heart atrial septation Atxn10tm1b(KOMP)Wtsi HOM E15.5 0.00
decreased bone mineral density Atxn10tm1b(KOMP)Wtsi HET Early adult 2.11×10-06
decreased bone mineral content Atxn10tm1b(KOMP)Wtsi HET Early adult 3.20×10-05
preweaning lethality, complete penetrance Atxn10tm1b(KOMP)Wtsi HOM Early adult 0.00
embryonic lethality prior to organogenesis Atxn10tm1b(KOMP)Wtsi HOM E9.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2) N/A
Uterus 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Atxn10tm1b(KOMP)Wtsi
kidney, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
trachea, HET, Male, WTSI
Atxn10tm1b(KOMP)Wtsi
testis, HET, Male, WTSI
Atxn10tm1b(KOMP)Wtsi
cartilage tissue, rib, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
peripheral nervous system, trigeminal V nerve, HET, Female, WTSI

View all 12 images

Atxn10tm1b(KOMP)Wtsi
kidney, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
trachea, HET, Male, WTSI
Atxn10tm1b(KOMP)Wtsi
testis, HET, Male, WTSI
Atxn10tm1b(KOMP)Wtsi
cartilage tissue, rib, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
pancreas, HET, Female, WTSI

View all 10 images

Atxn10tm1b(KOMP)Wtsi
peripheral nervous system, trigeminal V nerve, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
spinal cord, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
brainstem, HET, Male, WTSI
Atxn10tm1b(KOMP)Wtsi
testis, HET, Male, WTSI
Atxn10tm1b(KOMP)Wtsi
oviduct, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
kidney, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
urinary bladder, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
aorta, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
adrenal gland, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
cartilage tissue, rib, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
trachea, HET, Male, WTSI
Atxn10tm1b(KOMP)Wtsi
cartilage tissue, rib, HET, Female, WTSI
No Embryo expression data was found for this gene.

 Associated Images

DSS Histology
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
42 Images
Eye Morphology: Images Slit Lamp
3 Images
X-ray: XRay Images Whole Body Lateral Orientation
28 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
Anti-nuclear antibody assay
6 Images
Legacy Phenotype Associated Images
Atxn10tm1b(KOMP)Wtsi
HET, Male, WTSI
Atxn10tm1b(KOMP)Wtsi
HET, Male, WTSI
Atxn10tm1b(KOMP)Wtsi
HET, Male, WTSI
Atxn10tm1b(KOMP)Wtsi
HET, Male, WTSI
Atxn10tm1b(KOMP)Wtsi
HET, Male, WTSI

View all 126 images

Atxn10tm1b(KOMP)Wtsi
TS20 liver, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
TS20 skin, HET, Male, WTSI
Atxn10tm1b(KOMP)Wtsi
TS20 dorsal root ganglion, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
TS20 hindlimb, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
TS20 chorioallantoic placenta, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
fused cornea and lens, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
narrow eye opening, HET, Male, WTSI
Atxn10tm1b(KOMP)Wtsi
fused cornea and lens, HET, Female, WTSI
Atxn10tm1b(KOMP)Wtsi
abnormal coat/hair pigmentation, HET, Male, WTSI
Atxn10tm1b(KOMP)Wtsi
abnormal tail tip morphology, HET, Female, WTSI

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Atxn10tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Atxn10tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Atxn10tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Atxn10tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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