Gene: Pmm2

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Pmm2tm1b(EUCOMM)Hmgu HOM Early adult 0.00
embryonic lethality prior to organogenesis Pmm2tm1b(EUCOMM)Hmgu HOM E9.5 0.00
embryonic lethality prior to tooth bud stage Pmm2tm1b(EUCOMM)Hmgu HOM E12.5 0.00
enlarged lymph nodes Pmm2tm1b(EUCOMM)Hmgu HET Early adult 0.00
increased blood urea nitrogen level Pmm2tm1b(EUCOMM)Hmgu HET Early adult 8.77×10-05

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61) N/A
Brain 7  (6/504) N/A
Central nervous system ganglion 2  (1/70) N/A
Ear 7  (1/504) N/A
Embryo 7  (1/505) N/A
Eye 7  (1/504) N/A
Foot 7  (1/504) N/A
Forebrain 7  (1/504) N/A
Forelimb 7  (1/504) N/A
Gut 2  (1/56) N/A
Hand 7  (1/503) N/A
Head 7  (5/504) N/A
Heart 7  (1/504) N/A
Hindbrain 7  (6/504) N/A
Hindlimb 7  (1/503) N/A
Liver 7  (1/504) N/A
Lung 7  (1/500) N/A
Mandibular process 7  (1/504) N/A
Maxillary process 7  (1/504) N/A
Midbrain 7  (1/504) N/A
Nose 2  (1/70) N/A
Oral cavity 7  (1/504) N/A
2  (7/37)  (2/2) N/A
Skeleton 2  (1/70) N/A
Skin 7  (1/504) N/A
Spinal cord 2  (1/69) N/A
Tail 7  (1/504) N/A
Tail somite 7  (1/504) N/A
Trachea 2  (1/56) N/A
Urinary system 2  (1/56) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
28 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Eye Morphology: Images Ophthalmoscopy
4 Images
Gross Pathology and Tissue Collection
8 Images
Combined SHIRPA and Dysmorphology
1 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Pmm2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Pmm2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Pmm2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Pmm2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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