Gene: Rnf10

Log in to follow

Phenotype System Allele Zyg Sex Life Stage P Value
decreased cornea thickness Rnf10tm1b(KOMP)Wtsi HOM postnatal 1.26×10-05
increased circulating sodium level Rnf10tm1b(KOMP)Wtsi HOM postnatal 3.71×10-07
decreased circulating LDL cholesterol level Rnf10tm1b(KOMP)Wtsi HOM postnatal 8.62×10-05
abnormal retinal blood vessel morphology Rnf10em1(IMPC)Bay HOM postnatal 8.46×10-06
decreased startle reflex Rnf10em1(IMPC)Bay HOM postnatal 1.66×10-05
abnormal sleep behavior Rnf10tm1b(KOMP)Wtsi HOM postnatal 1.07×10-10
decreased circulating total protein level Rnf10tm1b(KOMP)Wtsi HOM postnatal 2.51×10-06
decreased startle reflex Rnf10tm1b(KOMP)Wtsi HOM postnatal 6.48×10-13
increased fluid intake Rnf10tm1b(KOMP)Wtsi HOM postnatal 5.76×10-07
hypoactivity Rnf10tm1b(KOMP)Wtsi HOM postnatal 2.36×10-06
increased NK cell number Rnf10tm1b(KOMP)Wtsi HOM postnatal 2.58×10-05
decreased lean body mass Rnf10em1(IMPC)Bay HOM postnatal 4.66×10-06
decreased total body fat amount Rnf10tm1b(KOMP)Wtsi HOM postnatal 6.92×10-09
decreased bone mineral content Rnf10tm1b(KOMP)Wtsi HOM postnatal 2.06×10-05
absent pinna reflex Rnf10tm1b(KOMP)Wtsi HOM postnatal 6.64×10-06
limb grasping Rnf10em1(IMPC)J HOM postnatal 6.76×10-05
increased lean body mass Rnf10tm1b(KOMP)Wtsi HOM postnatal 2.69×10-06
increased heart weight Rnf10tm1b(KOMP)Wtsi HET postnatal 4.06×10-06
increased cardiac muscle contractility Rnf10tm1b(KOMP)Wtsi HET postnatal 7.32×10-05
enlarged heart Rnf10tm1b(KOMP)Wtsi HET postnatal 0.00
increased heart left ventricle size Rnf10em1(IMPC)Bay HOM postnatal 1.23×10-05
decreased circulating glucose level Rnf10tm1b(KOMP)Wtsi HOM postnatal 4.94×10-07
increased circulating creatinine level Rnf10tm1b(KOMP)Wtsi HOM postnatal 1.60×10-06
decreased circulating cholesterol level Rnf10tm1a(KOMP)Wtsi HOM postnatal 1.94×10-05
decreased lean body mass Rnf10tm1b(KOMP)Wtsi HOM postnatal 1.77×10-14
thin ventricular wall Rnf10tm1b(KOMP)Wtsi HOM postnatal 1.30×10-06
increased or absent threshold for auditory brainstem response Rnf10tm1b(KOMP)Wtsi HOM postnatal 9.41×10-05
abnormal gait Rnf10tm1b(KOMP)Wtsi HOM postnatal 7.04×10-06
increased circulating cholesterol level Rnf10tm1a(KOMP)Wtsi HOM postnatal 1.94×10-05
decreased grip strength Rnf10tm1b(KOMP)Wtsi HOM postnatal 2.35×10-09
decreased circulating serum albumin level Rnf10tm1b(KOMP)Wtsi HOM postnatal 2.50×10-06
abnormal bone structure Rnf10tm1b(KOMP)Wtsi HOM postnatal 1.17×10-05
increased circulating triglyceride level Rnf10tm1a(KOMP)Wtsi HOM postnatal 6.07×10-05
preweaning lethality, incomplete penetrance Rnf10tm1b(KOMP)Wtsi HOM n/a 0.00
convulsive seizures Rnf10tm1b(KOMP)Wtsi HOM postnatal 4.05×10-05
abnormal retinal blood vessel morphology Rnf10tm1b(KOMP)Wtsi HET postnatal 6.22×10-06
decreased circulating HDL cholesterol level Rnf10tm1a(KOMP)Wtsi HOM postnatal 6.36×10-07
increased bone mineral content Rnf10tm1b(KOMP)Wtsi HOM postnatal 9.00×10-07
improved glucose tolerance Rnf10tm1b(KOMP)Wtsi HOM postnatal 2.07×10-05
decreased spleen weight Rnf10tm1b(KOMP)Wtsi HOM postnatal 9.65×10-05
increased KLRG1-positive NK cell number Rnf10tm1b(KOMP)Wtsi HOM postnatal 2.42×10-05
abnormal behavioral response to light Rnf10tm1b(KOMP)Wtsi HOM postnatal 9.95×10-07
decreased circulating creatinine level Rnf10tm1b(KOMP)Wtsi HET postnatal 5.14×10-05
abnormal kidney morphology Rnf10em1(IMPC)Mbp HOM postnatal 0.00
decreased prepulse inhibition Rnf10tm1b(KOMP)Wtsi HOM postnatal 1.17×10-05
decreased hemoglobin content Rnf10tm1b(KOMP)Wtsi HOM postnatal 8.80×10-06
increased red blood cell distribution width Rnf10tm1b(KOMP)Wtsi HOM postnatal 3.22×10-05
decreased circulating HDL cholesterol level Rnf10tm1b(KOMP)Wtsi HOM postnatal 3.69×10-09
increased bone mineral content Rnf10em1(IMPC)J HOM postnatal 2.09×10-06
decreased circulating cholesterol level Rnf10tm1b(KOMP)Wtsi HOM postnatal 3.88×10-09
decreased circulating triglyceride level Rnf10tm1b(KOMP)Wtsi HET postnatal 3.04×10-08
increased circulating HDL cholesterol level Rnf10tm1a(KOMP)Wtsi HOM postnatal 6.36×10-07
abnormal behavior Rnf10tm1b(KOMP)Wtsi HOM postnatal 3.67×10-13
increased circulating chloride level Rnf10tm1b(KOMP)Wtsi HOM postnatal 7.63×10-05
limb grasping Rnf10tm1b(KOMP)Wtsi HOM postnatal 1.90×10-06
decreased startle reflex Rnf10em1(IMPC)J HOM postnatal 3.04×10-09
decreased total retina thickness Rnf10tm1b(KOMP)Wtsi HOM postnatal 1.65×10-09
cataract Rnf10tm1b(KOMP)Wtsi HET postnatal 7.66×10-09
hyperactivity Rnf10tm1b(KOMP)Wtsi HOM postnatal 1.09×10-12
abnormal spleen morphology Rnf10tm1b(KOMP)Wtsi HOM postnatal 0.00
abnormal tibia morphology Rnf10tm1b(KOMP)Wtsi HOM postnatal 1.98×10-05
decreased mean corpuscular hemoglobin concentration Rnf10tm1b(KOMP)Wtsi HOM postnatal 2.70×10-05
decreased body length Rnf10tm1b(KOMP)Wtsi HOM postnatal 5.21×10-09
abnormal bone structure Rnf10em1(IMPC)J HOM postnatal 7.29×10-05
abnormal lens morphology Rnf10tm1b(KOMP)Wtsi HET postnatal 4.01×10-10
increased vertical activity Rnf10tm1b(KOMP)Wtsi HOM postnatal 1.52×10-06
decreased bone mineral density Rnf10tm1b(KOMP)Wtsi HOM postnatal 2.76×10-06
decreased circulating bilirubin level Rnf10tm1a(KOMP)Wtsi HOM postnatal 5.50×10-05
decreased circulating alkaline phosphatase level Rnf10tm1b(KOMP)Wtsi HOM postnatal 1.27×10-06

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 22 Yes  (2/584)  (18/24)  Wholemount images
Aorta 22 Yes  (16/24)  Wholemount images
Blood 6 No N/A
Blood vessel 4 No  (4/4) N/A
Bone 14 Yes  (2/16)  Wholemount images
Bone marrow 6 No N/A
Brain 22 Yes  (21/24)  Wholemount images  Section images
Brainstem 22 No  (15/24)  Wholemount images
Brown adipose tissue 22 Yes  (16/24)  Wholemount images
Cartilage tissue 22 No  (11/24)  Wholemount images
Cecum 12 Yes  (12/383)  (10/14)  Wholemount images
Cerebellum 22 No  (19/24)  Wholemount images  Section images
Cerebral cortex 22 No  (15/24)  Wholemount images
Chest bone 10 Yes  (10/12)  Wholemount images
Colon 10 No  (12/127)  (10/12) N/A
Cranium 6 No N/A
Diaphragm 10 Yes  (10/12)  Wholemount images
Duodenum 8 Yes  (2/127)  (8/10)  Wholemount images
Epididymis 12 Yes  (18/134)  (3/14)  Wholemount images
Esophagus 18 Yes  (7/415)  (16/20)  Wholemount images
Eye 22 Yes  (5/24)  Wholemount images
Gall bladder 18 Yes  (10/20)  Wholemount images
Gonadal fat pad 8 Yes  (7/10)  Wholemount images
Harderian gland 10 Yes  (10/12)  Wholemount images
Heart 22 Yes  (19/24)  Wholemount images
Hindlimb 10 Yes  (6/12)  Wholemount images
Hippocampus 22 No  (15/24)  Wholemount images
Hypothalamus 22 No  (15/24)  Wholemount images
Ileum 8 Yes  (14/127)  (9/10)  Wholemount images
Jejunum 8 Yes  (6/127)  (8/10)  Wholemount images
Kidney 22 Yes  (18/584)  (23/24)  Wholemount images
Large intestine 22 Yes  (10/584)  (17/24)  Wholemount images
Liver 22 Yes  (13/24)  Wholemount images
Lower urinary tract 22 No  (15/24)  Wholemount images
Lung 22 Yes  (18/24)  Wholemount images
Lymph node 22 Yes  Wholemount images
Main olfactory bulb 6 Yes  (6/8)  Wholemount images
Mammary gland 22 Yes  (4/24)  Wholemount images
Mesenteric adipose tissue 8 Yes  (8/10)  Wholemount images
Mesenteric lymph node 10 Yes  Wholemount images
Midbrain 10 No  (11/12) N/A
Esophagus 4 No  (4/4) N/A
Olfactory lobe 22 No  (17/24)  Wholemount images
Oral epithelium 10 No N/A
Ovary 22 Yes  (1/584)  (10/24)  Wholemount images
Oviduct 22 Yes  (10/24)  Wholemount images
Pancreas 22 Yes  (5/584)  (9/24)  Wholemount images
Parathyroid gland 18 Yes  (16/20)  Wholemount images
Parotid gland 10 Yes  (1/12)  Wholemount images
Penis 10 Yes  (5/12)  Wholemount images
Peripheral nervous system 22 No  (15/24)  Wholemount images
Peyer's patch 4 No N/A
Peyer's patch 18 No N/A
Pituitary gland 22 Yes  (17/24)  Wholemount images
Prostate gland 22 Yes  (12/584)  (8/24)  Wholemount images
Quadriceps 8 Yes  (10/10)  Wholemount images
Sciatic nerve 10 Yes  (4/12)  Wholemount images
Skeletal muscle 18 No  (15/20)  Wholemount images
Skeletal muscle tissue 4 No  (4/4) N/A
Skin 22 Yes  (16/24)  Wholemount images
Small intestine 22 No  (9/584)  (15/24)  Wholemount images
Spinal cord 22 Yes  (22/24)  Wholemount images
Spleen 22 Yes  (2/584)  (11/24)  Wholemount images
Stomach 22 Yes  (12/584)  (17/24)  Wholemount images
Stomach pyloric region 10 No N/A
Striatum 22 No  (15/24)  Wholemount images
Sublingual gland 10 Yes  (1/12)  Wholemount images
Submandibular gland 12 Yes  (2/132)  (3/14)  Wholemount images
Testis 22 Yes  (2/584)  (12/24)  Wholemount images
Thalamus 6 No  (7/8) N/A
Thymus 22 Yes  (1/24)  Wholemount images
Thyroid gland 22 Yes  (15/584)  (7/24)  Wholemount images
Tongue 10 Yes  (5/127)  (10/12)  Wholemount images
Trachea 22 Yes  (21/24)  Wholemount images
Trigeminal V nerve 12 Yes  (10/14)  Wholemount images
Urinary bladder 12 Yes  (11/14)  Wholemount images
Uterus 22 Yes  (10/24)  Wholemount images
Vagina 10 Yes  (3/12)  Wholemount images
Vas deferens 12 No  (15/388)  (2/14) N/A
Vascular system 18 No  (9/20)  Wholemount images
Vesicular gland 12 Yes  (3/14)  Wholemount images
White adipose tissue 22 Yes  (6/24)  Wholemount images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/47) N/A
Axial skeleton 2  (1/51) N/A
Brain 9  (6/485)  (8/12) N/A
Central nervous system ganglion 2  (1/51) N/A
Dorsal root ganglion 3  (1/47) N/A
Ear 9  (1/485)  (7/12) N/A
Embryo 9  (1/485)  (11/12)  Wholemount images
Outer ear 2  (1/47)  (2/2) N/A
Eye 9  (1/485)  (10/12)  Wholemount images
Foot 9  (1/485)  (4/12) N/A
Forearm 5  (1/282)  (5/5) N/A
Forebrain 9  (1/485)  (8/12)  Wholemount images
Forelimb 9  (1/485)  (11/12)  Wholemount images
Fronto-nasal process 3  (1/48)  (2/3) N/A
Gut 2  (1/50)  (2/2) N/A
Hand 9  (1/485)  (4/12) N/A
Head 9  (5/485)  (9/12)  Wholemount images
Head mesenchyme 2  (1/47) N/A
Heart 9  (1/485)  (4/12)  Wholemount images
Heart ventricle 2  (1/47) N/A
Hindbrain 9  (6/485)  (8/12) N/A
Hindlimb 9  (1/485)  (11/12)  Wholemount images
Intestine 2  (1/47)  (2/2) N/A
Liver 9  (1/485)  (2/12)  Wholemount images
Lower leg 5  (1/282)  (5/5) N/A
Lung 9  (1/485)  (2/12) N/A
Mandibular process 9  (1/485)  (8/12)  Wholemount images
Maxillary process 9  (1/485)  (8/12)  Wholemount images
Meckel's cartilage 2 N/A
Midbrain 9  (1/485)  (7/12)  Wholemount images
Nasal septum 2  (1/47) N/A
Nose 3  (1/51)  (3/3) N/A
Notochord 2  (1/47)  (2/2) N/A
Oral cavity 9  (1/485)  (3/12) N/A
Outflow tract 2  (1/47) N/A
Pericardium 1  (1/46) N/A
Pharynx 2  (1/46)  (2/2) N/A
2  (7/25) N/A
Radius-ulna pre-cartilage condensation 2  (1/46)  (2/2) N/A
Rib pre-cartilage condensation 2  (1/46) N/A
Skeleton 2  (1/51) N/A
Skin 9  (1/485)  (4/12) N/A
Spinal cord 3  (1/50)  (1/3) N/A
Tail 9  (1/485)  (11/12)  Wholemount images
Tail somite 9  (1/485)  (8/12) N/A
Thoracic vertebral cartilage condensation 2  (1/46) N/A
Tongue 2  (1/46) N/A
Trachea 1  (1/50) N/A
Trunk mesenchyme 2  (1/47) N/A
Upper arm 5  (1/282)  (3/5) N/A
Upper leg 5  (1/282)  (3/5) N/A
Vibrissa 2  (1/47)  (2/2) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
179 Images
X-ray: XRay Images Forepaw
50 Images
X-ray: XRay Images Lateral Orientation
153 Images
X-ray: XRay Images Skull Lateral Orientation
62 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
78 Images
Eye Morphology: Images Ophthalmoscopy
9 Images
Echo: M-Mode Images
32 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Gross Pathology and Tissue Collection
14 Images
Adult LacZ: LacZ Images Wholemount
505 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Liver - glycogen deposition Rnf10tm1b(KOMP)Wtsi HOM postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Rnf10em1(IMPC)Bay Exon Deletion Mice, Tissue
Rnf10em1(IMPC)J Exon Deletion Mice
Rnf10tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Rnf10tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Rnf10em1(IMPC)Mbp Indel causing a Frameshift Mutation Mice, Tissue
Rnf10tm303169(L1L2_Bact_P) Targeting vectors