Ech1 | enoyl coenzyme A hydratase 1, peroxisomal

GeneMGI:1858208Synonyms: dienoyl-CoA isomerase

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased total body fat amount2 supporting datasetsEch1tm1b(EUCOMM)WtsihomozygoteEarly adult1.08x10-5 
decreased lean body mass2 supporting datasetsEch1tm1b(EUCOMM)WtsihomozygoteEarly adult1.88x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ech1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Ech1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ech1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Ech1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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