Gene: Acsl4

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Name
acyl-CoA synthetase long-chain family member 4
MGI ID
MGI:1354713
Synonyms
Lacs4 ACS4 9430020A05Rik Facl4
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased body weight Acsl4tm1a(EUCOMM)Wtsi HEM   Early adult 5.80×10-08
decreased lean body mass Acsl4tm1a(EUCOMM)Wtsi HET   Early adult 6.77×10-05
thrombocytopenia Acsl4tm1a(EUCOMM)Wtsi HEM   Early adult 1.57×10-11
thrombocytopenia Acsl4tm1a(EUCOMM)Wtsi HET   Early adult 1.82×10-10
increased total body fat amount Acsl4tm1a(EUCOMM)Wtsi HET   Early adult 6.23×10-06
preweaning lethality, incomplete penetrance Acsl4tm1a(EUCOMM)Wtsi HOM   Early adult 0.00
decreased heart weight Acsl4tm1a(EUCOMM)Wtsi HET   Early adult 5.60×10-06
increased circulating cholesterol level Acsl4tm1a(EUCOMM)Wtsi HET   Early adult 4.97×10-05
decreased body length Acsl4tm1a(EUCOMM)Wtsi HOM   Early adult 5.78×10-05

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
5 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
5 Images
Histopathology
2 Images
X-ray: XRay Images Forepaw
4 Images
X-ray: XRay Images Skull Lateral Orientation
4 Images
X-ray: XRay Images Whole Body Dorso Ventral
5 Images
Legacy Phenotype Associated Images

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 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Liver - lipid deposition Acsl4tm1a(EUCOMM)Wtsi HOM Early adult
Liver - lipid deposition Acsl4tm1a(EUCOMM)Wtsi HET Early adult

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MGI Allele Allele Type Produced
Acsl4tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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