Acsl4 | acyl-CoA synthetase long-chain family member 4
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Growth/size/body region Limbs/digits/tail Hematopoietic system Skeleton Mortality/aging
13 No significant impact
4 Not tested
Data collections
Gene metrics:8Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal tibia morphology | 1 supporting dataset | Acsl4tm1a(EUCOMM)Wtsi | hemizygote | Early adult | 8.36x10-5 | ||
decreased circulating chloride level | 1 supporting dataset | Acsl4tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 7.07x10-5 | ||
increased total body fat amount | 1 supporting dataset | Acsl4tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 2.29x10-5 | ||
decreased body weight | 3 supporting datasets | Acsl4tm1a(EUCOMM)Wtsi | hemizygote | Early adult | 7.44x10-6 | ||
thrombocytopenia | 1 supporting dataset | Acsl4tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 9.29x10-5 | ||
decreased body length | 1 supporting dataset | Acsl4tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.1x10-11 | ||
preweaning lethality, incomplete penetrance | 1 supporting dataset | Acsl4tm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
| | | | | | | | | |
External links
No external links available for Acsl4.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
Acsl4tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |