Sirt6 | sirtuin 6
Physiological systems
19 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system
17 No significant impact
5 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased mean corpuscular hemoglobin concentration | 1 supporting dataset | Sirt6tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.94x10-5 | ||
increased circulating cholesterol level | 1 supporting dataset | Sirt6tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 9.4x10-7 |
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External links
No external links available for Sirt6.
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Sirt6tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
Sirt6tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Sirt6tm1c(EUCOMM)Wtsi | Wild type floxed exon (post-Flp) | | mouse |
Sirt6tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |