Gene: Siva1

Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
cataract Siva1tm1b(EUCOMM)Hmgu HOM postnatal 7.46×10-09
decreased heart left ventricle size Siva1tm1b(EUCOMM)Hmgu HOM postnatal 5.74×10-05
abnormal lens morphology Siva1tm1b(EUCOMM)Hmgu HOM postnatal 3.54×10-08

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 0 No  (2/584) N/A
Aorta 0 No N/A
Blood 0 No N/A
Bone 0 No N/A
Bone marrow 0 No N/A
Brain 0 Yes  (2/2)  Wholemount images
Brainstem 0 No N/A
Brown adipose tissue 0 No N/A
Cartilage tissue 0 No N/A
Cecum 0 No  (12/383) N/A
Cerebellum 0 No N/A
Cerebral cortex 0 No N/A
Chest bone 0 No N/A
Colon 0 No  (12/127) N/A
Cranium 0 No N/A
Diaphragm 0 No N/A
Epididymis 0 No  (18/134) N/A
Esophagus 0 No  (7/415) N/A
Eye 0 No N/A
Gall bladder 0 No N/A
Harderian gland 0 No N/A
Heart 0 Yes  (2/2)  Wholemount images
Hindlimb 0 No N/A
Hippocampus 0 No N/A
Hypothalamus 0 No N/A
Kidney 0 Yes  (18/584)  (2/2)  Wholemount images
Large intestine 0 No  (10/584) N/A
Liver 0 No N/A
Lower urinary tract 0 No N/A
Lung 0 No N/A
Lymph node 0 No N/A
Main olfactory bulb 0 No N/A
Mammary gland 0 No N/A
Mesenteric lymph node 0 No N/A
Olfactory lobe 0 No N/A
Oral epithelium 0 No N/A
Ovary 0 Yes  (1/584)  Wholemount images
Oviduct 0 No N/A
Pancreas 0 No  (5/584) N/A
Parathyroid gland 0 No N/A
Parotid gland 0 No N/A
Penis 0 No N/A
Peripheral nervous system 0 No N/A
Peyer's patch 0 No N/A
Pituitary gland 0 Yes  (2/2)  Wholemount images
Prostate gland 0 No  (12/584) N/A
Sciatic nerve 0 No N/A
Skeletal muscle 0 No N/A
Skin 0 No N/A
Small intestine 0 No  (9/584) N/A
Spinal cord 0 Yes  (2/2)  Wholemount images
Spleen 0 No  (2/584) N/A
Stomach 0 Yes  (12/584)  (2/2)  Wholemount images
Stomach pyloric region 0 No N/A
Striatum 0 No N/A
Sublingual gland 0 No N/A
Submandibular gland 0 Yes  (2/132)  (1/2)  Wholemount images
Testis 0 Yes  (2/584)  (1/2)  Wholemount images
Thymus 0 No N/A
Thyroid gland 0 Yes  (15/584)  (2/2)  Wholemount images
Tongue 0 No  (5/127) N/A
Trachea 0 No N/A
Trigeminal V nerve 0 No N/A
Urinary bladder 0 Yes  Wholemount images
Uterus 0 Yes  Wholemount images
Vagina 0 No N/A
Vas deferens 0 Yes  (15/388)  Wholemount images
Vascular system 0 No N/A
Vesicular gland 0 Yes  Wholemount images
White adipose tissue 0 Yes  (1/2)  Wholemount images
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Dorso Ventral
4 Images
X-ray: XRay Images Lateral Orientation
4 Images
Adult LacZ: LacZ Images Wholemount
19 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Siva1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Siva1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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