Genes Phenotypes

Gene: Pik3cg

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Name
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
MGI ID
MGI:1353576
Synonyms
PI3K PI(3)Kgamma PI3Kgamma p110gamma 5830428L06Rik
Viability
N/A
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (1) Measurements chart (141) All data table (237)
Expression & images (45) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating alanine transaminase level Pik3cgtm1a(EUCOMM)Wtsi HOM Early adult 1.84×10-05

Download data as:  TSV  XLS

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No N/A
Esophagus 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584)  (1/2) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No  (1/2) N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Pik3cgtm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
spleen, HET, Female, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
brain, HET, Male, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
peyer's patch, HET, Female, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
mesenteric lymph node, lymph node, HET, Female, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
spleen, HET, Female, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
peyer's patch, HET, Female, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
mesenteric lymph node, lymph node, HET, Female, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
spleen, HET, Female, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
peyer's patch, HET, Female, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
peyer's patch, HET, Female, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
brain, HET, Male, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images
Pik3cgtm1a(EUCOMM)Wtsi
head, WT, Male, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
body, WT, Male, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
head, WT, Male, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
body, WT, Male, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
body, WT, Male, WTSI

View all 113 images

Pik3cgtm1a(EUCOMM)Wtsi
abnormal retinal pigmentation, left eye, HOM, Female, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
eye, cataracts, HOM, Female, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
persistence of hyaloid vascular system, HOM, Female, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
eye, corneal opacity, cornea/lens fusion, HOM, Female, WTSI
Pik3cgtm1a(EUCOMM)Wtsi
back skin, HOM, Female, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Pik3cgtm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Pik3cgtm1c(EUCOMM)Wtsi Wild type floxed exon (post-Flp) Mice

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