Genes Phenotypes

Gene: Iqgap1

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Name
IQ motif containing GTPase activating protein 1
MGI ID
MGI:1352757
Synonyms
D7Ertd257e D7Ertd237e
Viability
Homozygous - Viable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (205) All data table (310)
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
hypoactivity Iqgap1tm1b(EUCOMM)Wtsi HOM postnatal 2.41×10-05
short tibia Iqgap1tm1b(EUCOMM)Wtsi HOM postnatal 6.51×10-10
increased grip strength Iqgap1tm1b(EUCOMM)Wtsi HOM postnatal 8.03×10-05
abnormal bone structure Iqgap1tm1b(EUCOMM)Wtsi HOM postnatal 1.66×10-05
decreased bone mineral density Iqgap1tm1b(EUCOMM)Wtsi HOM postnatal 2.68×10-09
decreased bone mineral content Iqgap1tm1b(EUCOMM)Wtsi HOM postnatal 7.60×10-08

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Iqgap1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Iqgap1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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