Genes Phenotypes

Gene: Fscn1

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Name
fascin actin-bundling protein 1
MGI ID
MGI:1352745
Synonyms
fascin-1 Fan1
Viability
Homozygous - Subviable
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (195) All data table (559)
Expression & images (104) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo size Fscn1tm1.1(KOMP)Vlcg HET E12.5 0.00
hyperactivity Fscn1tm1.1(KOMP)Vlcg HET Early adult 4.89×10-15
preweaning lethality, incomplete penetrance Fscn1tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal behavior Fscn1tm1.1(KOMP)Vlcg HET Early adult 7.35×10-12

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 3 No  (2/584)  (3/3)  Section images
Aorta 3 No N/A
Blood 1 No N/A
Bone 2 No  (2/2) N/A
Bone marrow 1 No N/A
Brain 3 No  (2/3)  Section images
Brainstem 3 No N/A
Brown adipose tissue 1 No  (1/1)  Section images
Cartilage tissue 3 No N/A
Cecum 3 No  (12/379)  (2/3) N/A
Cerebellum 3 No  (1/3)  Section images
Cerebral cortex 3 No  (2/3) N/A
Chest bone 1 No N/A
Colon 1 No  (12/127)  (1/1)  Section images
Diaphragm 1 No  (1/1)  Section images
Duodenum 1 No  (2/127) N/A
Epididymis 1 No  (18/134)  (1/1)  Section images
Esophagus 3 No  (7/415)  (1/3)  Section images
Eye 3 No  (3/3)  Section images
Gall bladder 1 No N/A
Gonadal fat pad 1 No  (1/1)  Section images
Harderian gland 1 No N/A
Heart 3 No  (2/3)  Section images
Hindlimb 1 No N/A
Hippocampus 3 No N/A
Hypothalamus 3 No N/A
Ileum 1 No  (14/127)  (1/1)  Section images
Jejunum 1 No  (6/127) N/A
Kidney 3 No  (18/584)  (3/3)  Section images
Large intestine 3 No  (10/584) N/A
Liver 3 No  (3/3)  Section images
Lower urinary tract 3 No N/A
Lung 3 No  (1/3)  Section images
Lymph node 3 No N/A
Mammary gland 3 No N/A
Mesenteric adipose tissue 1 No  (1/1)  Section images
Mesenteric lymph node 1 No N/A
Midbrain 1 No  (1/1)  Section images
Olfactory lobe 3 No  (2/3)  Section images
Ovary 3 No  (1/584) N/A
Oviduct 3 No N/A
Pancreas 3 No  (5/584)  (3/3)  Section images
Parathyroid gland 1 No N/A
Parotid gland 1 No N/A
Penis 1 No  (1/1)  Section images
Peripheral nervous system 3 No  (2/3) N/A
Peyer's patch 3 No  (2/3)  Section images
Pituitary gland 3 No N/A
Prostate gland 3 No  (12/584)  (2/3)  Section images
Quadriceps 1 No  (1/1)  Section images
Sciatic nerve 1 No  (1/1)  Section images
Skeletal muscle 3 No  (2/3)  Section images
Skin 3 No  (1/3)  Section images
Small intestine 3 No  (9/584) N/A
Spinal cord 3 No  (3/3)  Section images
Spleen 3 No  (2/584)  (3/3)  Section images
Stomach 3 No  (12/584) N/A
Stomach pyloric region 1 No N/A
Striatum 3 No N/A
Sublingual gland 1 No N/A
Submandibular gland 1 No  (2/132) N/A
Testis 3 No  (2/584)  (1/3)  Section images
Thymus 3 No  (2/3)  Section images
Thyroid gland 3 No  (15/584)  (2/3) N/A
Tongue 1 No  (5/127)  (1/1)  Section images
Trachea 3 No N/A
Trigeminal V nerve 1 No  (1/1)  Section images
Urinary bladder 1 No N/A
Uterus 3 No N/A
Vagina 1 No N/A
Vas deferens 1 No  (15/388) N/A
Vascular system 3 No N/A
Vesicular gland 1 No N/A
White adipose tissue 3 No  (2/3)  Section images
LacZ Wholemount Images
LacZ Section Images
Unassigned Top Level MA (12)
adipose tissue (6)
Brown adipose tissue expression
MA:0000057
cardiovascular system (2)
Heart expression
MA:0000072
digestive system (14)
Colon expression
MA:0000335
endocrine system (1)
Adrenal gland expression
MA:0000116
exocrine system (1)
Prostate gland expression
MA:0000404
immune system (9)
Peyers Patch expression
MA:0000137
integumental system (1)
Skin expression
MA:0000151
limb (2)
Sciatic nerve expression
MA:0001172
musculoskeletal system (6)
Diaphragm expression
MA:0001904
nervous system (17)
Brain expression
MA:0000168
postnatal mouse (72)
Adrenal gland expression
MA:0000116
reproductive system (9)
Epididymis expression
MA:0000397
respiratory system (6)
Diaphragm expression
MA:0001904
sensory organ (8)
Eye expression
MA:0000261
set of connective tissues (6)
Brown adipose tissue expression
MA:0000057
trunk (40)
Adrenal gland expression
MA:0000116
urinary system (3)
Kidney expression
MA:0000368
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61)  (2/2) N/A
Brain 5  (6/504)  (2/8) N/A
Central nervous system ganglion 2  (1/70)  (2/2) N/A
Ear 5  (1/504)  (2/8) N/A
Embryo 5  (1/505)  (2/8) N/A
Eye 5  (1/504)  (2/8) N/A
Foot 5  (1/504)  (2/8) N/A
Forebrain 5  (1/504)  (2/8) N/A
Forelimb 5  (1/504)  (2/8) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 5  (1/503)  (2/8) N/A
Head 5  (5/504)  (2/8) N/A
Heart 5  (1/504)  (2/8) N/A
Hindbrain 5  (6/504)  (2/8) N/A
Hindlimb 5  (1/503)  (2/8) N/A
Liver 5  (1/504)  (2/8) N/A
Lung 5  (1/500)  (2/8) N/A
Mandibular process 5  (1/504)  (2/8) N/A
Maxillary process 5  (1/504)  (2/8) N/A
Midbrain 5  (1/504)  (2/8) N/A
Nose 2  (1/70)  (2/2) N/A
Oral cavity 5  (1/504)  (2/8) N/A
5  (7/37)  (8/8) N/A
Skeleton 2  (1/70)  (2/2) N/A
Skin 5  (1/504)  (2/8) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Tail 5  (1/504)  (2/8) N/A
Tail somite 5  (1/504)  (2/8) N/A
Trachea 2  (1/56)  (2/2) N/A
Urinary system 2  (1/56)  (2/2) N/A

 Associated Images

Adult LacZ: LacZ Images Section
84 Images
Embryo LacZ: LacZ images wholemount
32 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Fscn1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Fscn1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Fscn1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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