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Genes Phenotypes

Gene: Bag3

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Name
BCL2-associated athanogene 3
MGI ID
MGI:1352493
Synonyms
Bcl-2-interacting death suppressor Bis
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (308) All data table (704)
Expression & images (67) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased blood urea nitrogen level Bag3tm1b(EUCOMM)Hmgu HET Early adult 2.37×10-09
preweaning lethality, complete penetrance Bag3tm1b(EUCOMM)Hmgu HOM   Early adult 0.00
decreased monocyte cell number Bag3tm1a(EUCOMM)Hmgu HET   Early adult 1.89×10-05
decreased lean body mass Bag3tm1b(EUCOMM)Hmgu HET Early adult 1.07×10-06

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (3/590)  (4/4)  Wholemount images
Aorta 4 No  (1/590)  (4/4)  Wholemount images
Bone 4 No  (4/4)  Wholemount images
Brain 4 No  (3/590)  (4/4)  Wholemount images
Brainstem 4 No  (2/590)  (2/4) N/A
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No  (4/4)  Wholemount images
Cerebellum 4 No  (3/590)  (4/4)  Wholemount images
Cerebral cortex 4 No  (2/590)  (1/4) N/A
Esophagus 4 No  (7/415)  (4/4)  Wholemount images
Eye 4 No  (4/4)  Wholemount images
Gall bladder 4 No  (4/4)  Wholemount images
Heart 4 No  (1/590)  (4/4)  Wholemount images
Hippocampus 4 No  (3/590)  (2/4) N/A
Hypothalamus 4 No  (2/590)  (4/4)  Wholemount images
Kidney 4 No  (20/590)  (4/4)  Wholemount images
Large intestine 4 No  (10/590)  (4/4)  Wholemount images
Liver 4 No N/A
Lower urinary tract 4 No  (1/590)  (4/4)  Wholemount images
Lung 4 No  (1/590)  (4/4)  Wholemount images
Lymph node 4 No N/A
Mammary gland 4 No N/A
Olfactory lobe 4 No  (2/590)  (4/4)  Wholemount images
Oral epithelium 4 No  (1/4) N/A
Ovary 4 No  (1/590)  (1/4)  Wholemount images
Oviduct 4 No  (1/4)  Wholemount images
Pancreas 4 No  (5/590)  (4/4)  Wholemount images
Parathyroid gland 4 No  (4/4)  Wholemount images
Peripheral nervous system 4 No  (1/590)  (4/4)  Wholemount images
Peyer's patch 4 No  (3/4)  Wholemount images
Pituitary gland 4 No  (1/590)  (2/4)  Wholemount images
Prostate gland 4 No  (12/590)  (2/4)  Wholemount images
Skeletal muscle 4 No N/A
Skin 4 No  (4/4)  Wholemount images
Small intestine 4 No  (9/590)  (4/4)  Wholemount images
Spinal cord 4 No  (2/590)  (4/4)  Wholemount images
Spleen 4 No  (2/590) N/A
Stomach 4 No  (13/590)  (4/4)  Wholemount images
Striatum 4 No  (3/590)  (2/4)  Wholemount images
Testis 4 No  (5/590)  (2/4)  Wholemount images
Thymus 4 No N/A
Thyroid gland 4 No  (16/590) N/A
Trachea 4 No  (2/590)  (4/4)  Wholemount images
Uterus 4 No  (2/4)  Wholemount images
Vascular system 4 No  (4/4)  Wholemount images
White adipose tissue 4 No N/A
LacZ Wholemount Images
cardiovascular system (2)
Cartilage tissue expression
Vascular System expression
Bone expression
MA:0002718
MA:0000104
MA:0001459
digestive system (5)
Gall Bladder expression
MA:0000356
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (1)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
immune system (1)
Small Intestine expression
Peyers Patch expression
MA:0000137
MA:0000337
integumental system (1)
Skin expression
MA:0000151
musculoskeletal system (1)
Cartilage tissue expression
Vascular System expression
Bone expression
MA:0002718
MA:0000104
MA:0001459
nervous system (5)
Brain expression
Cerebellum expression
Hypothalamus expression
Olfactory Lobe expression
Striatum expression
MA:0000198
MA:0000891
MA:0000168
MA:0002413
MA:0000173
postnatal mouse (22)
Adrenal gland expression
MA:0000116
reproductive system (3)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
respiratory system (2)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (2)
Cartilage tissue expression
Vascular System expression
Bone expression
MA:0002718
MA:0000104
MA:0001459
trunk (15)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/506) N/A
Ear 1  (1/506) N/A
Embryo 1  (1/507)  (1/1) N/A
Eye 1  (1/506) N/A
Foot 1  (1/506)  (1/1) N/A
Forebrain 1  (1/506) N/A
Forelimb 1  (1/506) N/A
Hand 1  (1/506)  (1/1) N/A
Head 1  (5/506)  (1/1) N/A
Heart 1  (1/506)  (1/1) N/A
Hindbrain 1  (6/506) N/A
Hindlimb 1  (1/506) N/A
Liver 1  (1/504) N/A
Lung 1  (1/504) N/A
Mandibular process 1  (1/506) N/A
Maxillary process 1  (1/506) N/A
Midbrain 1  (1/506) N/A
Oral cavity 1  (1/504) N/A
Skin 1  (1/506) N/A
Tail 1  (1/506)  (1/1) N/A
Tail somite 1  (1/506)  (1/1) N/A

 Associated Images

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Embryo LacZ: LacZ images wholemount
4 Images
thumbnail
Adult LacZ: LacZ Images Wholemount
22 Images
thumbnail
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
thumbnail
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
thumbnail
Echo: M-Mode Images
28 Images
thumbnail
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Bag3tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Bag3tm1c(EUCOMM)Hmgu Wild type floxed exon (post-Flp) Mice
Bag3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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