Genes Phenotypes

Gene: Nr2c2

Name
nuclear receptor subfamily 2, group C, member 2
MGI ID
MGI:1352466
Synonyms
Tr4 TAK1
Viability
Homozygous - Subviable
Other links
MGI   Ensembl  
Significant phenotypes (6) All measurements (697) Expression & images (113) Disease models (0) Order (3)
View data by physiological system
Significant
Not Significant
Not tested
Body weight
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal neural tube closure Nr2c2tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal embryo turning Nr2c2tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
embryonic lethality prior to tooth bud stage Nr2c2tm1b(EUCOMM)Wtsi HOM embryonic day 12.5 0.00
embryonic growth retardation Nr2c2tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
preweaning lethality, incomplete penetrance Nr2c2tm1b(EUCOMM)Wtsi HOM n/a 0.00
abnormal pharyngeal arch morphology Nr2c2tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Bone 2 No  (2/2) N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cecum 2 No  (12/383) N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle 2 No  (2/2) N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Trigeminal V nerve 2 No  (2/2) N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388)  (1/2) N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
nervous system (1)
Cerebral Cortex expression
Brain expression
Striatum expression
Hippocampus expression
Hypothalamus expression
Cerebellum expression
Brainstem expression
Olfactory Lobe expression
MA:0000185
MA:0000168
MA:0000891
MA:0000191
MA:0000173
MA:0000198
MA:0000169
MA:0002413
postnatal mouse (1)
Cerebral Cortex expression
Brain expression
Striatum expression
Hippocampus expression
Hypothalamus expression
Cerebellum expression
Brainstem expression
Olfactory Lobe expression
MA:0000185
MA:0000168
MA:0000891
MA:0000191
MA:0000173
MA:0000198
MA:0000169
MA:0002413
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/47)  (2/2) N/A
Axial skeleton 2  (1/51)  (2/2) N/A
Brain 2  (6/485)  (2/2) N/A
Central nervous system ganglion 2  (1/51)  (2/2) N/A
Cranium 2  (1/46)  (2/2) N/A
Dorsal root ganglion 2  (1/47)  (2/2) N/A
Ear 2  (1/485)  (2/2) N/A
Embryo 2  (1/485)  (2/2) N/A
Outer ear 2  (1/47)  (2/2) N/A
Eye 2  (1/485)  (2/2) N/A
Femur pre-cartilage condensation 2  (1/46)  (2/2) N/A
Foot 2  (1/485)  (2/2) N/A
Forearm 2  (1/282)  (2/2) N/A
Forebrain 2  (1/485)  (2/2) N/A
Forelimb 2  (1/485)  (2/2) N/A
Fronto-nasal process 2  (1/48)  (2/2) N/A
Gut 2  (1/50)  (2/2) N/A
Hand 2  (1/485)  (2/2) N/A
Head 2  (5/485)  (2/2) N/A
Head mesenchyme 2  (1/47)  (2/2) N/A
Heart 2  (1/485)  (2/2) N/A
Heart ventricle 2  (1/47)  (2/2) N/A
Hindbrain 2  (6/485)  (2/2) N/A
Hindlimb 2  (1/485)  (2/2) N/A
Humerus pre-cartilage condensation 2  (1/46)  (2/2) N/A
Inner ear 2  (1/46)  (2/2) N/A
Intestine 2  (1/47)  (2/2) N/A
Liver 2  (1/485)  (2/2) N/A
Lower leg 2  (1/282)  (2/2) N/A
Lung 2  (1/485)  (2/2) N/A
Mandibular process 2  (1/485)  (2/2) N/A
Maxillary process 2  (1/485)  (2/2) N/A
Mesonephros of female 2  (1/46)  (1/2) N/A
Mesonephros of male 2  (1/46)  (1/2) N/A
Metanephros 2  (1/46)  (2/2) N/A
Midbrain 2  (1/485)  (2/2) N/A
Nasal septum 2  (1/47)  (2/2) N/A
Nose 2  (1/51)  (2/2) N/A
Notochord 2  (1/47)  (2/2) N/A
Oral cavity 2  (1/485)  (2/2) N/A
Outflow tract 2  (1/47)  (2/2) N/A
Pancreas 2  (1/46)  (2/2) N/A
Pericardium 2  (1/46)  (2/2) N/A
Pharynx 2  (1/46)  (2/2) N/A
Radius-ulna pre-cartilage condensation 2  (1/46)  (2/2) N/A
Rib pre-cartilage condensation 2  (1/46)  (2/2) N/A
Skeleton 2  (1/51)  (2/2) N/A
Skin 2  (1/485)  (2/2) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Stomach 2  (1/46)  (2/2) N/A
Tail 2  (1/485)  (2/2) N/A
Tail somite 2  (1/485)  (2/2) N/A
Thoracic vertebral cartilage condensation 2  (1/46)  (2/2) N/A
Tongue 2  (1/46)  (2/2) N/A
Trachea 2  (1/50)  (2/2) N/A
Trunk mesenchyme 2  (1/47)  (2/2) N/A
Umbilical artery embryonic part 2  (1/47)  (2/2) N/A
Umbilical vein embryonic part 2  (1/47)  (2/2) N/A
Upper arm 2  (1/282)  (2/2) N/A
Upper leg 2  (1/282)  (2/2) N/A
Urinary system 2  (1/50)  (2/2) N/A
Vibrissa 2  (1/47)  (2/2) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Nr2c2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Nr2c2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Nr2c2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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