Gene: Abcc2

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Name
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
MGI ID
MGI:1352447
Synonyms
multidrug resistance protein 2 Mrp2 Cmoat
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased mean corpuscular hemoglobin Abcc2tm2b(KOMP)Wtsi HOM Early adult 1.33×10-08
decreased grip strength Abcc2tm2b(KOMP)Wtsi HOM   Early adult 6.78×10-05
increased circulating bilirubin level Abcc2tm2b(KOMP)Wtsi HOM Early adult 1.41×10-11
increased kidney weight Abcc2tm2b(KOMP)Wtsi HOM Early adult 3.79×10-13
decreased mean platelet volume Abcc2tm2b(KOMP)Wtsi HOM Early adult 5.22×10-07
decreased mean corpuscular volume Abcc2tm2b(KOMP)Wtsi HOM   Early adult 1.87×10-05
increased circulating cholesterol level Abcc2tm2b(KOMP)Wtsi HOM   Early adult 6.25×10-05

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Select physiological systems to view:
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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (4/583) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (7/407) N/A
2 No N/A
2 No  (2/2)  Wholemount images
2 No  (2/583) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (21/583)  (2/2)  Wholemount images
2 No  (10/583) N/A
2 No  (2/2)  Wholemount images
2 No  (1/583) N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No N/A
2 No  (5/583) N/A
2 No  (1/563) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (12/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (9/583) N/A
2 No  (3/583) N/A
2 No  (3/583) N/A
2 No  (13/583)  (2/2)  Wholemount images
2 No  (3/583) N/A
2 No  (6/583)  (1/2)  Wholemount images
2 No  (1/583) N/A
2 No  (17/583)  (1/2)  Wholemount images
2 No  (3/583) N/A
2 No N/A
2 No N/A
2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
1  (6/505) N/A
1  (1/505) N/A
1  (1/506) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (5/505) N/A
1  (1/505) N/A
1  (6/505) N/A
1  (1/505) N/A
1  (1/503) N/A
1  (1/503) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/503) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A

 Associated Images

Echo: M-Mode Images
32 Images
X-ray: XRay Images Whole Body Dorso Ventral
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
12 Images
Adult LacZ: LacZ Images Wholemount
5 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Abcc2tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Abcc2tm2b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Abcc2tm44698(L1L2_gt0) Targeting vectors
Abcc2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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