Gene: Abcc2

Name
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
MGI ID
MGI:1352447
Synonyms
Cmoat Mrp2 multidrug resistance protein 2
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased mean corpuscular volume Abcc2tm2b(KOMP)Wtsi HOM postnatal 1.77×10-05
increased kidney weight Abcc2tm2b(KOMP)Wtsi HOM postnatal 2.17×10-12
decreased mean corpuscular hemoglobin Abcc2tm2b(KOMP)Wtsi HOM postnatal 1.83×10-06
decreased mean platelet volume Abcc2tm2b(KOMP)Wtsi HOM postnatal 1.69×10-07
increased circulating bilirubin level Abcc2tm2b(KOMP)Wtsi HOM postnatal 3.18×10-08

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584) N/A
Liver 2 No  (2/2)  Wholemount images
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (1/2)  Wholemount images
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485) N/A
Ear 1  (1/485) N/A
Embryo 1  (1/485) N/A
Eye 1  (1/485) N/A
Foot 1  (1/485) N/A
Forebrain 1  (1/485) N/A
Forelimb 1  (1/485) N/A
Hand 1  (1/485) N/A
Head 1  (5/485) N/A
Heart 1  (1/485) N/A
Hindbrain 1  (6/485) N/A
Hindlimb 1  (1/485) N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) N/A
Mandibular process 1  (1/485) N/A
Maxillary process 1  (1/485) N/A
Midbrain 1  (1/485) N/A
Oral cavity 1  (1/485) N/A
Skin 1  (1/485) N/A
Tail 1  (1/485) N/A
Tail somite 1  (1/485) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
12 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
Echo: M-Mode Images
32 Images
X-ray: XRay Images Lateral Orientation
12 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Adult LacZ: LacZ Images Wholemount
5 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Abcc2tm2b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Abcc2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Abcc2tm44698(L1L2_gt0) Targeting vectors
Abcc2tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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