Gene: Abcb11

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ATP-binding cassette, sub-family B (MDR/TAP), member 11
Bsep PFIC2 PGY4 Lith1 sister of P-glycoprotein ABC16
Embryo Screen
Other links
Expression & images (0) Disease models (0) Order (3)
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal behavior Abcb11tm1b(EUCOMM)Hmgu HET postnatal 5.13×10-06
abnormal lung morphology Abcb11tm1b(EUCOMM)Hmgu HET postnatal 0.00
increased lean body mass Abcb11tm1a(EUCOMM)Hmgu HOM postnatal 3.02×10-05
abnormal retina morphology Abcb11tm1a(EUCOMM)Hmgu HOM postnatal 1.26×10-07
preweaning lethality, incomplete penetrance Abcb11tm1b(EUCOMM)Hmgu HOM n/a 0.0455

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Expression data not available

 Associated Images

X-ray: XRay Images Lateral Orientation
12 Images
X-ray: XRay Images Dorso Ventral
13 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Abcb11tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Abcb11tm27268(L1L2_gt1) Targeting vectors
Abcb11tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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