Genes Phenotypes

Gene: Abca3

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Name
ATP-binding cassette, sub-family A (ABC1), member 3
MGI ID
MGI:1351617
Synonyms
ABC-C 1810036E22Rik Abc3
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (1) Measurements chart (129) All data table (527)
Expression & images (113) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Abca3tm1b(EUCOMM)Hmgu HOM Early adult 0.00

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No  (2/2) N/A
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cecum 2 No  (12/379)  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No  (2/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (2/2) N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2) N/A
Parathyroid gland 2 No  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No  (2/2) N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Trigeminal V nerve 2 No  (2/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  Wholemount images
Vas deferens 2 No  (15/388)  (1/2) N/A
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (2)
Vascular System expression
Cartilage tissue expression
Bone expression
MA:0002718
MA:0000104
MA:0001459
endocrine system (1)
Adrenal gland expression
MA:0000116
integumental system (1)
Skin expression
MA:0000151
musculoskeletal system (2)
Vascular System expression
Cartilage tissue expression
Bone expression
MA:0002718
MA:0000104
MA:0001459
postnatal mouse (5)
Adrenal gland expression
MA:0000116
reproductive system (1)
Ovary expression
Oviduct expression
Uterus no expression
MA:0000384
MA:0000385
MA:0000389
set of connective tissues (2)
Vascular System expression
Cartilage tissue expression
Bone expression
MA:0002718
MA:0000104
MA:0001459
trunk (2)
Adrenal gland expression
MA:0000116
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/57)  (2/2) N/A
Axial skeleton 2  (1/61) N/A
Brain 2  (6/504)  (2/2) N/A
Central nervous system ganglion 2  (1/70)  (2/2) N/A
Cranium 2  (1/61) N/A
Dorsal root ganglion 2  (1/57)  (2/2) N/A
Ear 2  (1/504)  (2/2) N/A
Embryo 2  (1/505)  (2/2) N/A
Outer ear 2  (1/66)  (2/2) N/A
Eye 2  (1/504)  (2/2) N/A
Femur pre-cartilage condensation 2  (1/52) N/A
Foot 2  (1/504)  (2/2) N/A
Forearm 2  (1/297) N/A
Forebrain 2  (1/504)  (2/2) N/A
Forelimb 2  (1/504)  (2/2) N/A
Fronto-nasal process 2  (1/58)  (2/2) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 2  (1/503)  (2/2) N/A
Head 2  (5/504)  (2/2) N/A
Head mesenchyme 2  (1/57)  (2/2) N/A
Heart 2  (1/504)  (2/2) N/A
Heart ventricle 2  (1/57)  (2/2) N/A
Hindbrain 2  (6/504)  (2/2) N/A
Hindlimb 2  (1/503)  (2/2) N/A
Humerus pre-cartilage condensation 2  (1/61) N/A
Inner ear 2  (1/61)  (2/2) N/A
Intestine 2  (1/55) N/A
Liver 2  (1/504)  (2/2) N/A
Lower leg 2  (1/297) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504) N/A
Mesonephros of female 2  (1/52) N/A
Mesonephros of male 2  (1/52) N/A
Metanephros 2  (1/52) N/A
Midbrain 2  (1/504)  (2/2) N/A
Nasal septum 2  (1/57)  (2/2) N/A
Nose 2  (1/70)  (2/2) N/A
Notochord 2  (1/57)  (2/2) N/A
Oral cavity 2  (1/504) N/A
Outflow tract 2  (1/57)  (2/2) N/A
Pancreas 2  (1/52) N/A
Pericardium 2  (1/52)  (2/2) N/A
Pharynx 2  (1/52)  (2/2) N/A
Radius-ulna pre-cartilage condensation 2  (1/61) N/A
Rib pre-cartilage condensation 2  (1/54) N/A
Skeleton 2  (1/70) N/A
Skin 2  (1/504) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Stomach 2  (1/52) N/A
Tail 2  (1/504)  (2/2) N/A
Tail somite 2  (1/504)  (2/2) N/A
Thoracic vertebral cartilage condensation 2  (1/52) N/A
Tongue 2  (1/52) N/A
Trachea 2  (1/56) N/A
Trunk mesenchyme 2  (1/57)  (2/2) N/A
Umbilical artery embryonic part 2  (1/57)  (2/2) N/A
Umbilical vein embryonic part 2  (1/57)  (2/2) N/A
Upper arm 2  (1/297) N/A
Upper leg 2  (1/297) N/A
Urinary system 2  (1/56) N/A
Vibrissa 2  (1/66) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
5 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Abca3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Abca3tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Abca3tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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