Gene: Nup62

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased total body fat amount Nup62tm1b(KOMP)Wtsi HET Early adult 3.19×10-07
increased bone mineral content Nup62tm1b(KOMP)Wtsi HET Early adult 2.96×10-06
decreased total retina thickness Nup62tm1b(KOMP)Wtsi HET Early adult 8.62×10-23
abnormal retinal outer nuclear layer morphology Nup62tm1b(KOMP)Wtsi HET   Early adult 9.80×10-05
preweaning lethality, complete penetrance Nup62tm1b(KOMP)Wtsi HOM   Early adult 0.00
abnormal retinal inner nuclear layer morphology Nup62tm1b(KOMP)Wtsi HET Early adult 2.62×10-14
increased exploration in new environment Nup62tm1b(KOMP)Wtsi HET Early adult 1.68×10-06
increased lean body mass Nup62tm1b(KOMP)Wtsi HET Early adult 2.83×10-06
increased cornea thickness Nup62tm1b(KOMP)Wtsi HET   Early adult 9.99×10-05

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2)  Wholemount images
Aorta 2 No  (1/583)  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (4/583)  (2/2)  Wholemount images
Brainstem 2 No  (2/583)  (2/2)  Wholemount images
Brown adipose tissue 2 No  (2/2)  Wholemount images
Cartilage tissue 2 No  (1/583)  (2/2)  Wholemount images
Cecum 1 No  (12/371)  (1/1) N/A
Cerebellum 2 No  (3/583)  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/583)  (2/2)  Wholemount images
Esophagus 2 No  (7/407)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (2/583)  (2/2)  Wholemount images
Hippocampus 2 No  (3/583)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/583)  (2/2)  Wholemount images
Kidney 2 No  (21/583)  (2/2)  Wholemount images
Large intestine 2 No  (10/583)  (2/2)  Wholemount images
Liver 2 No  (2/2)  Wholemount images
Lower urinary tract 2 No  (1/583)  (2/2)  Wholemount images
Lung 2 No  (2/583)  (2/2) N/A
Lymph node 2 No  (1/583)  (2/2) N/A
Mammary gland 2 No  (1/2)  Wholemount images
Mesenteric lymph node 2 No  (2/2)  Wholemount images
Olfactory lobe 2 No  (2/583)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/583)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/583)  (2/2)  Wholemount images
Parathyroid gland 2 No  (1/563)  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/583)  (2/2)  Wholemount images
Peyer's patch 2 No  (2/2)  Wholemount images
Pituitary gland 2 No  (1/583)  (1/2)  Wholemount images
Prostate gland 2 No  (12/583)  (1/2)  Wholemount images
Skeletal muscle 2 No  (2/2)  Wholemount images
Skin 2 No  (1/583)  (2/2)  Wholemount images
Small intestine 2 No  (9/583)  (2/2)  Wholemount images
Spinal cord 2 No  (3/583)  (2/2) N/A
Spleen 2 No  (3/583)  (2/2)  Wholemount images
Stomach 2 No  (13/583)  (2/2)  Wholemount images
Striatum 2 No  (3/583)  (2/2)  Wholemount images
Testis 2 No  (6/583)  (1/2)  Wholemount images
Thymus 2 No  (1/583)  (2/2)  Wholemount images
Thyroid gland 2 No  (17/583)  (2/2)  Wholemount images
Trachea 2 No  (3/583)  (2/2)  Wholemount images
Trigeminal V nerve 2 No  (2/2)  Wholemount images
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2)  Wholemount images
Vas deferens 2 No  (15/382)  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No  (2/2)  Wholemount images
No Embryo expression data was found for this gene.

 Associated Images

Eye Morphology: VIP of right fundus
15 Images
X-ray: XRay Images Forepaw
10 Images
Eye Morphology: VIP of left eye
16 Images
Adult LacZ: LacZ Images Wholemount
30 Images
Eye Morphology: VIP of left fundus
16 Images
Eye Morphology: VIP of right eye
16 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Nup62tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Nup62tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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