Gene: Grm6

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Name
glutamate receptor, metabotropic 6
MGI ID
MGI:1351343
Synonyms
mGluR6 nerg1 nob3
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased heart weight Grm6tm1b(EUCOMM)Wtsi HOM Early adult 1.57×10-08
abnormal eye morphology Grm6tm1b(EUCOMM)Wtsi HOM Early adult 0.00
hyperactivity Grm6tm1b(EUCOMM)Wtsi HOM Early adult 6.35×10-06
increased kidney weight Grm6tm1b(EUCOMM)Wtsi HOM Early adult 8.94×10-07
impaired pupillary reflex Grm6tm1b(EUCOMM)Wtsi HOM Early adult 3.96×10-22
cataract Grm6tm1b(EUCOMM)Wtsi HOM Early adult 1.90×10-05
increased circulating triglyceride level Grm6tm1b(EUCOMM)Wtsi HOM Early adult 9.32×10-06
mydriasis Grm6tm1b(EUCOMM)Wtsi HOM Early adult 4.00×10-22

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Echo: M-Mode Images
32 Images
Adult LacZ: LacZ Images Wholemount
2 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Whole Body Dorso Ventral
12 Images
X-ray: XRay Images Whole Body Lateral Orientation
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
X-ray: XRay Images Skull Lateral Orientation
1 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Grm6tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Grm6tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Grm6tm434(L1L2_gt0) Targeting vectors

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