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Genes Phenotypes

Gene: Grm3

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Name
glutamate receptor, metabotropic 3
MGI ID
MGI:1351340
Synonyms
mGluR3 0710001G23Rik Gprc1c mGlu3
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (5) Measurements chart (234) All data table (430)
Expression & images (67) Disease models (0) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating cholesterol level Grm3tm1b(KOMP)Wtsi HOM Early adult 3.49×10-05
microphthalmia Grm3tm1b(KOMP)Wtsi HOM Early adult 0.00
increased circulating HDL cholesterol level Grm3tm1b(KOMP)Wtsi HOM Early adult 2.07×10-05
increased circulating triglyceride level Grm3tm1b(KOMP)Wtsi HOM Early adult 1.95×10-05
decreased bone mineral content Grm3tm1b(KOMP)Wtsi HOM Early adult 3.79×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Bone 2 No N/A
Brain 2 No  (3/590)  (2/2)  Wholemount images
Brainstem 2 No  (2/590)  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590)  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/590)  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/590)  (2/2)  Wholemount images
Kidney 2 No  (20/590) N/A
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/590)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/590)  (1/2)  Wholemount images
Oviduct 2 No N/A
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590)  (2/2)  Wholemount images
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590) N/A
Striatum 2 No  (3/590)  (2/2)  Wholemount images
Testis 2 No  (5/590)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (16/590)  (1/2)  Wholemount images
Trachea 2 No  (2/590) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
Unassigned Top Level MA (7)
Brain expression
Brainstem expression
Cerebral Cortex expression
Cerebellum expression
Hippocampus expression
Hypothalamus expression
Olfactory Lobe expression
Striatum expression
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (4/4) N/A
Ear 2  (1/506) N/A
Embryo 2  (1/507)  (4/4) N/A
Eye 2  (1/506) N/A
Foot 2  (1/506) N/A
Forebrain 2  (1/506)  (1/4) N/A
Forelimb 2  (1/506) N/A
Hand 2  (1/506) N/A
Head 2  (5/506)  (4/4) N/A
Heart 2  (1/506) N/A
Hindbrain 2  (6/506)  (2/4) N/A
Hindlimb 2  (1/506) N/A
Liver 2  (1/504) N/A
Lung 2  (1/504) N/A
Mandibular process 2  (1/506) N/A
Maxillary process 2  (1/506) N/A
Midbrain 2  (1/506)  (4/4) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/506) N/A
Tail 2  (1/506) N/A
Tail somite 2  (1/506) N/A

 Associated Images

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Immunophenotyping: Panel B FCS file(s)
8 Images
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Echo: M-Mode Images
32 Images
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X-ray: XRay Images Whole Body Lateral Orientation
10 Images
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Immunophenotyping: Panel A FCS file(s)
8 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
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X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
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Embryo LacZ: LacZ images wholemount
8 Images
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Adult LacZ: LacZ Images Wholemount
7 Images
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X-ray: XRay Images Skull Lateral Orientation
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Grm3tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Grm3tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Grm3tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Grm3tm208463(L1L2_Pgk_P) Targeting vectors

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